ALTERATION OF FHR PATTERN ASSOCIATED WITH PROGRESSIVELY ADVANCED FETAL ACIDEMIA CAUSED BY CORD COMPRESSION
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概要
- 論文の詳細を見る
臍帯圧迫が繰り返されることにより児はacidemiaになつていくが, その時どのようなFHR patternの変化がみられるかを調べる目的でヒツジ胎仔慢性実験モデルを作製し実験を行った. 繰り返し臍帯を圧迫することにより胎仔動脈血pHは7.35より6.90まで漸次下降し, lactate濃度も約50mg/dlまで上昇した. このさいみられるFHR patternをその特徴的変化により5型に分類した. またこの臍帯圧迫のさいの胎児動脈血中のcatecholamine濃度の変化や, 硫酸アトロピン, alpha, beta-受容体antagonistらの薬剤投与によるFHR patternの変化から, これらの特徴的変化には胎児交感神経・副交感神経の強い関与が示唆された. 特に, 第4型は, pH7.15付近のacidemiaで出現し, deceleration中のinitial drop の減少, hypoxia-induced deceleration及びovershoot accelerationの出現らの特微がみられる. 従つて, FHR monitoring上このようなpatternがみられる時になんらかのinterventionをしなければ児のacidemiaは益々進行し, 重篤な障害をきたすものと思われる.
- 社団法人日本産科婦人科学会の論文
- 1988-06-01
著者
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Sato Akira
Department of Cardiology, Yokosuka Kyosai Hospital
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YAJIMA AKIRA
Department of Obstetrics and Gynecology, Tohoku University School of Medicine
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OKAMURA Kunihiro
Department of Obstetrics and Gynecology, Tohoku University Graduate School of Medicine
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WATANABE Takanori
Department of Surgery, Hoshi General Hospital
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ENDO Chikara
Department of Obstetrics and Gynecology, Tohoku University School of Medicine
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AKAGI Kozo
Department of Obstetrics and Gynecology, Tohoku University School of Medicine
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SAITO Junya
Department of Obstetrics and Gynecology, Tohoku University School of Medicine
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Yajima Akira
Department Of Obstetrics And Gynecology Tohoku University School Of Medicine
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TANIGAWARA Shingo
Department of Obstetrics and Gynecology, Tohoku University School of Medicine
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SHINTAKU Yoshiyuki
Department of Obstetrics and Gynecology, Tohoku University School of Medicine
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AKIYAMA Naomichi
Department of Obstetrics and Gynecology, Tohoku University School of Medicine
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WATANABE TAKANORI
Sendai Municipal Hospital
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TANIGAWARA SHINGO
Sendai Red Cross Hospital
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Akagi Kozo
Department Of Obstetrics And Gynecology Tohoku University School Of Medicine
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Saito Junya
Department Of Obstetrics And Gynecology Tohoku University School Of Medicine
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Endo Chikara
Department Of Obstetrics And Gynecology Tohoku University School Of Medicine
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Endo Chikara
Department Of Obstetrics And Gynecology Fukushima Medical College
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Watanabe Takanori
Department Of Obstetrics And Gynecology Tohoku University School Of Medicine
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Watanabe Takanori
Department Of General Medicine And Cardiology Graduate School Of Medicine Osaka City University
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Tanigawara Shingo
Department Of Obstetrics And Gynecology Tohoku University School Of Medicine
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Akiyama Naomichi
Department Of Obstetrics And Gynecology Tohoku University School Of Medicine
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Shintaku Yoshiyuki
Department Of Obstetrics And Gynecology Tohoku University School Of Medicine
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Okamura Kunihiko
Center For Perinatal Medicine Tohoku University Hospital
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Okamura Kunihiro
Department Of Obstetrics And Gynecology Tohoku University
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Sato Akira
Department Of Obstetrics And Gynecology Fukushima Medical College
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Watanabe Takanori
Department Of Biochemistry Osaka City University Medical School
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Sato Akira
Department Of Applied Chemistry And Molecular Science Iwate University
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Okamura Kunihiro
Department Of Gynecology And Obstetrics Tohoku University Hospital
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Sato Akira
Department Of Advanced Surgical Science And Technology Tohoku University
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