HLA適合血小板輸血が奏功した骨髄異形成症候群合併妊娠の1例

概要

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We describe herein a 32-year old japanese women, with primipara of pregnancy complicated with refractory anemia type of myelodysplastic syndrome(MDS), inevitably requiring repeated HLA-type compatible platelet transfusion as treatment for frequent nasal bleeding and purpura occurring in the third trimester of gestation, with successful outcome in both mother and newborn. Our patient had a peculiar past history of repeated blood and/or platelet transfusion, leading to the production of anti-HLA antibody. The newborn was free from neonatal alloimmune thrombocytopenic purpura. In MDS such as this, HLA-type compatible platelet treatment is an effective was of controlling the condition throughout gestation to labor.
社団法人日本産科婦人科学会の論文
1998-10-01