胆道拡張症における合流異常部および十二指腸乳頭部の機能

概要

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Measurements of intraluminal pressure of the bile duct and amylase in bile were performed in 3 patients with congenital choledochal dilatation associated with anomalous junction of pancreatico-biliary ductal system. The values of amylase in bile were 46,500S.R.U., 27,850S.R.U., and 7,290S.R.U., respectively. These values were abnormally high. Before administration of gastrin and secretin a high pressure zone was found in the sphincter of Oddi. However, it was found neither in the common channel nor in the anomalous junction. A rsting pressure of the sphincter of Oddi increased 3 minutes after administration of tetragastrin. However, no pressure change was found in the anomalous junction after administration of gastrin. On the other hand, it was shown that secretin decreased the resting pressure of sphincter of Oddi. Thus, no sphincter function, as was found in the sphincter of Oddi, was not observed in the anomalous junction of pancreatico-biliary ductal system. Therefore, it seems that this anomalous junction allows reflux of pancreatic juice into the common bile duct or reflux of bile into the pancreatic duct corresponding to the pressure gradient.
特定非営利活動法人日本小児外科学会の論文
1986-06-20