Analysis of Rad51 in the Social Amoeba Dictyostelium Discoideum : Sequence, Induction and Disruption
スポンサーリンク
概要
- 論文の詳細を見る
The cellular slime mold Dictyostelium discoideum, a lower eukaryote feeding on bacteria in soil, is highly resistant to DNA damaging agents. D. discoideum expresses at least two RecA homologs, Rad51 and mitochondria localizing RecA. Rad51 consisting of 351 amino acid residues is 69% identical to human Rad51. UV light-irradiation and H_2O_2-treatment increased the expression level of Rad51, suggesting that Rad51 is required for DNA repair in D. discoideum. A gene disruption mutant was not viable, suggesting that Rad51 is essential for D. discoideum.
著者
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NAKAMURA Shogo
Department of Physics, Faculty of Engineering, Yokohama National University
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Shinohara Hiroaki
Division Of Bioengineering Faculty Of Engineering Toyama University
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Kodaira K
Division Of Bioengineering Faculty Of Engineering Toyama University
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HASEGAWA YASUNA
Division of Bioengineering, Faculty of Engineering, Toyama University
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YASUKAWA HIRO
Division of Bioengineering, Faculty of Engineering, Toyama University
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ARIMITSU TOSHIO
Division of Bioengineering, Faculty of Engineering, Toyama University
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KODAIRA KENICHI
Division of Bioengineering, Faculty of Engineering, Toyama University
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Arimitsu Toshio
Division Of Bioengineering Faculty Of Engineering Toyama University
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Yasukawa Hiro
Division Of Bio Engineering Faculty Of Engineering Toyama University
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Nakamura Shogo
Department Of Biology Faculty Of Science Toyama University
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Nakamura Shogo
Department Of Environmental Biology And Chemistry Faculty Of Science Toyama University
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