顎骨用吸収性骨接合材料について : 高強度PLLA材料を中心として

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The application of metallic plates and screws for internal bone fixation is accepted with disadvantages, such as the bone atrophy from stress, and the ionization of metal. Because of these disadvantages, we usually remove the devices six months after the first operation. To substitute the metallic materials, we have developed new resorbable osteosynthesis systems for maxillofacial surgery. Polyglycolide (PGA), polylactide (PLA) and polydioxanone (PDS) are biodegradable substances used for surgical materials and PLA is considered the most suitable for bone fixation because it is the strongest. PLA are made from lactic acid polymers. Poly-L-lactide (PLLA) materials, such as SR-PLLA, As-polymerized PLLA and High-strength PLLA, are used clinically. Our High-strength PLLA material has lower molecular weight and crystallinity but it is stronger than the other PLLA materials. We treated 51 patients with mandible fractures and other oral diseases, using High-strength PLLA plates or screws. Follow-up studies were done by clinical, radiographic and laboratory examinations. After passing more than 2 years following operation, in 13 of the 20 cases the plates were palpable through soft tissue. However, the healing of the bone wound was uneventful in every case through our follow up period. These results lead us to conclude that our PLLA osteosynthesis system can be considered safe and useful for internal fixation in maxillofacial surgery.
岩手医科大学歯学会の論文
2005-08-16

顎骨用吸収性骨接合材料について : 高強度PLLA材料を中心として

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