Survey of Carcinogenicity Studies of the Pharmaceuticals in Rodents
スポンサーリンク
概要
- 論文の詳細を見る
- 日本トキシコロジー学会の論文
- 1998-10-07
著者
-
MUTAI Mamoru
Toxicology Laboratory, Life Science Research Sector, Mitsubishi Chemical Co. Yokohama Research Cente
-
Sato Motonobu
Japan Pharmaceutical Manufacturers Association (jpma)
-
YASUBA MASASHI
Japan Pharmaceutical Manufacturers Association
-
AOKI Toyohiko
Japan Pharmaceutical Manufacturers Association
-
Mutai Mamoru
Japan Pharmaceutical Manufacturers Association (jpma)
-
Mutai Mamoru
Toxicol.lab.life Sci.res.sect.mitsubishi Chemical Co. Ltd.
-
Aoki Toyohiko
Drug Safety Research Laboratories Eisai Co. Ltd.)
-
Irimura Kenji
Japan Pharmaceutical Manufacturers Association (jpma)
-
Usui Toshimi
Japan Pharmaceutical Manufacturers Association (jpma)
-
MATSUZAWA TOSHIAKI
Japan Pharmaceutical Manufacturers Association
-
KOGA Teruji
Japan Pharmaceutical Manufacturers Association (JPMA), Tokyo, Japan
-
NAGAYAMA Satoshi
Japan Pharmaceutical Manufacturers Association (JPMA), Tokyo, Japan
-
FUJII Toshiyuki
Japan Pharmaceutical Manufacturers Association (JPMA), Tokyo, Japan
-
YAMASHITA Satoru
Japan Pharmaceutical Manufacturers Association (JPMA), Tokyo, Japan
-
Koga Teruji
Japan Pharmaceutical Manufacturers Association (jpma)
-
Fujii Toshiyuki
Japan Pharmaceutical Manufacturers Association (jpma)
-
Nagayama Satoshi
Japan Pharmaceutical Manufacturers Association (jpma)
-
Yasuba Masashi
Japan Pharmaceutical Manufacturers Association (jpma)
-
Matsuzawa Toshiaki
Japan Pharmaceutical Manufacturers Association (jpma)
-
Yamashita Satoru
Japan Pharmaceutical Manufacturers Association (jpma)
関連論文
- Dose-dependent Promoting Effects of Catechol on Glandular Stomach Carcinogenesis in BALB/c Mice Initiated with N-Methyl-N-nitrosourea
- P8-29 The left lobe model as an improved mouse pulmonary fibrosis model by intratracheal bleomycin administration(STATISTICAL AND TEST METHODS/LOCAL STIMURATION)(GENERAL SESSION BY POSTER PRESENTATION)(Proceedings of the 31st Annual Meeting)
- Practical use of ICH guidelines for special toxicology studies : Questionnaire survey by JPMA.(GENERAL SESSION BY ORAL PRESENTATION)(GENOTOXICITY)
- P-60 Current Status of Hematology in General Toxicity Studies for Pharmaceuticals.(Proceedings of the 27th Annual Meeting)
- P-59 Current Status of Clinical Chemistry in General Toxicology Studies for Pharmaceuticals.(Proceedings of the 27th Annual Meeting)
- P-58 Current Status of Urinalysis in General Toxicity Studies for Pharmaceuticals.(Proceedings of the 27th Annual Meeting)
- O-8 Current Status of Clinical Pathology Testings in General Toxicity Studies for Pharmaceuticals.(Proceedings of the 27th Annual Meeting)
- MECHANISTIC STUDY ON INHIBITION OF SERUM THYROID HORMONE PRODUCTION BY THIOUREA
- Questionnaire survey of application in S7A Safety Pharmacology Guideline (Part 2) : Point of GLP (STATISTICAL METHODS) (GENERAL SESSION BY POSTER PRESENTATION) (Proceedings of the 30th Annual Meeting)
- Questionnaire survey of application in S7A Safety Pharmacology Guideline (Part 1) : Point of experimental items (STATISTICAL METHODS) (GENERAL SESSION BY POSTER PRESENTATION) (Proceedings of the 30th Annual Meeting)
- Survey of Carcinogenicity Studies of the Pharmaceuticals in Rodents
- A Comparision of the Results of Rat and Mouse Carcinogenicity Studies Conducted on Pharmaceuticals
- Questionnaire survey on cardiac electrophysiology examination in safety pharmacology studies.(GENERAL SESSION BY POSTER PRESENTATION)(SAFETY PHARMACOLOGY)
- 22A-10-3 Detection of Dibromoacetic acid-induced histopathological changes in testes and epididymides of rats by 2-weeks repeated dose toxicity study.
- 21C-10-2 Detection of carcinogenic potential of Diethylstibestrol (DES) and N-methyl-N-nitrosourea (MNU) by the alternative testing model using Tg-rasH2 mouse
- Survey of pharmacology study conduct using outside sources in pharmaceutical companies in Japan.(GENERAL SESSION BY ORAL PRESENTATION)(MINI SYMPOSIUM : CONSIDERATION OF OUTSOURCINGS AND MONITORING IN NON-CLINICAL STUDY(CURRENT SURVEY))
- Study Monitor : The Surveillance of Outsourced Non-Clinical Studies : Draft Report, Final Report, Archives, and Quality Assurance(GENERAL SESSION BY ORAL PRESENTATION)(MINI SYMPOSIUM : CONSIDERATION OF OUTSOURCINGS AND MONITORING IN NON-CLINICAL STUDY(CUR
- Study monitor : the Surveillance of Outsourced Non-Clinical Studies (Reproductive Studies,Pathology and Toxicokinetics).(GENERAL SESSION BY ORAL PRESENTATION)(MINI SYMPOSIUM : CONSIDERATION OF OUTSOURCINGS AND MONITORING IN NON-CLINICAL STUDY(CURRENT SURV
- Study Monitor. The Surveillance of Outsourced Non-Clinical Studies : Testing facility checking, Protocol, Formulation and In-life phase(GENERAL SESSION BY ORAL PRESENTATION)(MINI SYMPOSIUM : CONSIDERATION OF OUTSOURCINGS AND MONITORING IN NON-CLINICAL STU
- Study Monitor. Introduction of the Surveillance for Outsourcing Non-Clinical Studies and Summary of Toxicology.(GENERAL SESSION BY ORAL PRESENTATION)(MINI SYMPOSIUM : CONSIDERATION OF OUTSOURCINGS AND MONITORING IN NON-CLINICAL STUDY(CURRENT SURVEY))
- Effect of dosing interval between edaravone and cefalotin/glycerol on the nephrotoxicity in rats(Kidney, Urinary system, Proceedings of the 32nd Annual Meeting)
- P7-14 Renal Toxicity of Furosemide in Rats : Effects of Water-Deprived Condition or Coadministration of Cefalotin and Glycerol(IMMUNE AND ALLERGIC SYSTEM/KIDNEYS AND URINARY EXCRETION SYSTEM/CYTOTOXICITY/OTHERS-1)(GENERAL SESSION BY POSTER PRESENTATION)(P
- O-22 Nephrotoxic effect of edaravone in combination with cefalotin and glycerol in rats(KIDNEYS AND URINARY EXCRETION SYSTEM)(GENERAL SESSION BY ORAL PRESENTATION)(Proceedings of the 31st Annual Meeting)
- P11-09 Glucose Alters the Susceptibility of Mesangial Cells to Contrast Media.
- Species differences between rats and dogs in LPS-stimulated Kupffer cells and monocytes.(GENERAL SESSION BY POSTER PRESENTATION)(LIVER AND DIGESTIVE SYSTEM)
- KUPFFER CELL- MEDIATED CYTOTOXICITY INDUCED BY LIPOPOLYSACCHARIDE0111:B4 IS GREATER IN DOGS THAN IN RATS AND MONKEYS
- PEROXISOME PROLIFERATOR-ACTIVATED RECEPTOR α(PPARα)AGONIST, WY-14, 643, INCREASED TRANSCRIPTION OF MYOSIN LIGHT CHAIN-2 IN CARDIOMYOCYTES
- Up-regulation of oxidative stress responsive genes in the rat kidney glomerulus following single intravenous dose of puromycin aminonucleoside (PAN) (TOXICOGENOMICS AND TOXICOPROTEOMICS) (GENERAL SESSION BY POSTER PRESENTATION) (Proceedings of the 30th An
- Metabonomic analysis of rat urine following single dose of α-naphthylisothiocyanate (ANIT) or puromycin aminonucleoside (PAN) (TOXICOGENOMICS AND TOXICOPROTEOMICS) (GENERAL SESSION BY POSTER PRESENTATION) (Proceedings of the 30th Annual Meeting)
- 3B-06 Study on the blood chemistry parameters in CD(SD)IGS rats.
- ORIGIN OF SERUM ALP ISOZYME AND IT CHANGE DURING THE FASTING IN BEAGLE DOGS.
- Gene expression profiling of rat kidneys following dose of edaravone in combination with cefalotin and glycerol(Kidney, Urinary system, Proceedings of the 32nd Annual Meeting)
- COLLABORATIVE WORK TO EVALUATE TOXICITY ON MALE REPRODUCTIVE ORGANS BY REPEATED DOSE STUDIES IN RATS : 25)EFFECTS OF 2- AND 4- WEEK REPEATED-DOSING OF DIBROMOACETIC ACID
- Gene expression profiling in rat primary-cultured hepatocytes exposed to chemicals causing mitochondrial dysfunction (TOXICOGENOMICS AND TOXICOPROTEOMICS) (GENERAL SESSION BY POSTER PRESENTATION) (Proceedings of the 30th Annual Meeting)
- Preliminary investigation in application of microarray technique to toxicity evaluation using rat primary-cultured hepatocytes.(GENERAL SESSION BY POSTER PRESENTATION)(MOLECULAR TOXICITY & TOXICOGENOMICS)
- Summary of Questionnaire Surveys of Toxicokinetics in Pharmaceutical Industries in Japan.(GENERAL SESSION BY ORAL PRESENTATION)(MINI SYMPOSIUM : STRATEGIC TOXICOKINETICS ON DRUG DISCOVERY(CURRENT SURVEY))
- Responsibility of Monitor for Quality Assurance of Outsourcing Non-clinical Studies.(GENERAL SESSION BY ORAL PRESENTATION)(MINI SYMPOSIUM : CONSIDERATION OF OUTSOURCINGS AND MONITORING IN NON-CLINICAL STUDY(CURRENT SURVEY))
- Report 4 : CASE STUDY OF CARCINOGENICITY BY INITIATION-PROMOTION MODEL (CARCINOGENlClTY STUDIES)
- P11-13 Questionnaire Survey of Functional Observational Battery in Domestic and Foreign Non-clinical Contract Research Organization.
- O10-18 Questionnaire Survey of Functional Observational Battery in Domestic and Foreign Non-clinical Contract Research Organization.
- P11-01 Development of in vitro assay for drug-induced myocardial hypertrophy
- Practical use of ICH guidelines for carcinogenicity studies : Questionnaire survey by JPMA.(GENERAL SESSION BY POSTER PRESENTATION)(CARCINOGENICITY)
- SS-3 Welfare of laboratory animals and toxicology research in Japanese pharmaceutical companies(SATELLITE SYMPOSIUM: TOXICOLOGY AND BIOETHICS)(Proceedings of the 31st Annual Meeting)
- O-25 Cytotoxic effects of edaravone in human renal cells(KIDNEYS AND URINARY EXCRETION SYSTEM)(GENERAL SESSION BY ORAL PRESENTATION)(Proceedings of the 31st Annual Meeting)
- O10-04 Stability studies for urinary ALP, gamma-GT, LDH and creatinine measurement in rats.