Effect of Etoposide on Cell Cycle Progression in L1210 Murine Ascites Tumor
スポンサーリンク
概要
- 論文の詳細を見る
We examined the effect of etoposide on cell cycle progression in L1210 murine ascites tumor. Cell cycle analysis was examined by flow cytometer. At 3 and 6 hr after administration of etoposide, the percentage of the S-phase increased to more than 1.3-fold as compared to that of the control . At 10 hr, cells were piled up in G_2 + M Phase, and S-phase decreased. Since ara-C is a drug with a cell cycle S-phase specific action, these results might explain the enhanced incorporation of ara-C by pretreatment with etoposide that we reported previously.
- 日本医療薬学会の論文
- 1996-04-10
著者
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SAKURAI MINORU
Department of Orthopaedic Surgery, School of Medicine, Tohoku University
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HAMAZAKI Yutaka
Department of Pathology, Shizuoka Children's Hospital
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OOI Kazuya
Department of Hospital Pharmacy, Faculty of Pharmaceutical Sciences, Josai University
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Taniguchi Kiyosu
Department Of Pediatrics Mie University School Of Medicine
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Sakurai Minoru
Department Of Pediatrics Mie University School Of Medicine
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Kawasaki Hajime
Department Of Pediatrics Mie University School Of Medicine
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Kawasaki Hajime
Department Of Pediatrics
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Hamazaki Yutaka
Department Of Clinical Pathology Shizuoka Children's Hospital
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Ooi Kazuya
Department Of Pharmacy Yokkaichi Social Insurance Hospital
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Ooi Kazuya
Department Of Hospital Pharmacy Faculty Of Pharmaceutical Sciences Josai University
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HIGASHIGAWA MASAMUNE
Department of Pediatrics, Mie University School of Medicine
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OHKUBO Toshiki
Department of Pediatrics, Mie University School of Medicine
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Higashigawa M
Mie Univ. Mie Jpn
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Higashigawa Masamune
Department Of Pediatrics Mie University School Of Medicine
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Ohkubo Toshiki
Department Of Pediatrics Mie University School Of Medicine
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Sakurai Minoru
Department Of Orthopaedic Surgery School Of Medicine Tohoku University
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Sakurai Minoru
Department Of Biomolecular Engineering Tokyo Institute Of Technology
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