重要な相互作用の検討 : 日米における薬物間相互作用の評価の比較

概要

論文の詳細を見る
Our hospital receives many drug interaction reports from all over the world. But many physicians tend to overlook many drug interactions. In order to provide appropriate drug therapy, we examined the Japanese Pharmaceutical Reference (JPR) to evaluate drug interactions for approximately 2000 medicines, which are used at our hospital. We compared our evaluations with those found in the Physicians Desk Reference (PDR) and the Drug Interaction Fact (DIF), which are both American references. We thus found 76 incompatible drug combinations located in the JPR, while there are 80 drug combinations found in the DIF. 16 drug combinations are classified similarly between the JPR and the DIF. In addition, the PDR classifies 6 drug categories with incompatible drug combinations among the 8 drug categories found in the JPR and DIF. Our study concludes that differences exist between Japan and America concerning drug interaction evaluations.
日本医療薬学会の論文
2002-06-10