Toxicokinetic Analysis of Injected Diazinon and Diazoxon in Resistant and Susceptible Houseflies, Musca domestica L.

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概要

• 論文の詳細を見る

• The internal dynamics of diazinon and diazoxon when administered by injection were studied in a susceptible and resistant strain of housefly. Fliers which received diazinon by injection showed only a small interstrain difference in the internal amount of diazinon. In contrast, large interstrain difference was observed in the internal amount of diazoxon when the fliers received diazinon or diazoxon by injection. Several kinetic models were postulated and examined to describe the internal dynamics of diazinon. Interstrain comparison of the kinetic parameter values estimated by computer simulation revealed that high degradation of diazoxon played an important role. It is also suggested that high degradation of diazinon and less activation are responsible for the decreased accumulation of diazoxon.

• 日本応用動物昆虫学会の論文
• 1993-02-25

著者

• Motoyama Naoki

  The Department Of Advanced Materials Science The University Of Tokyo

• DAUTERMAN Walter

  Department of Toxicology, North Carolina State University

• Dauterman Walter

  Department Of Toxicology North Carolina State University

• OI Masanori

  ILaboratory of Environmental Biology, Faculty of Horticulture, Chiba University

• MOTOYAMA Naoki

  Laboratory of Environmental Biology, Faculty of Horticulture, Chiba University

• Oi Masanori

  Ilaboratory Of Environmental Biology Faculty Of Horticulture Chiba University:yuki Research Center N

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