ウィスター系とオズボーン系ラットから分離したmutans streptococciの性状とう蝕原性の比較研究

概要

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Two mutans streptococci strains designated WS1 and OS1 were isolated from Wistar-albino and Osborne-mendel rats, respectively. The two strains differ in biochemical characterization ; WS1 was characterized by hydrolysis of arginine, resistance to bacitracin, and it does not ferment starch and glycogen; OS1 showed no hydrolysis of arginine, but sensitivity to bacitracin and fermentation of starch and glycogen. Serotypes of the WS1 and OS1 strains were investigated with immunodiffusion: WS1 showed serotype b to react with anti b serum, but a serotype for OS1 could not be demonstrated by reaction with antisera to serotypes a toh. The OS1 reacted with anti 5. ferus serum, suggesting that WS1 and OS1 were S. rattus and S. ferus, respectively. The final pH of each strain after incubation in a medium including 1% glucose was 4.44 with WS1 and 4.28 with OS1, these pH values were almost the same as with standard strains derived from rats. Other standard strains showed lower pH than the standard and isolated strains of rats, and their acidogenicity was weak. The cariogenicity of the two strains were investigated by isolating streptomycin resistant strains and inoculation to intersect each of the strains of rats. The results indicated that WS1 was strongly cariogenic in Wistar-albino rats, and OS1 was strongly cariogenic in Osborne-mendel rats, suggesting a relation between the strains isolated and the host rats.
1997-06-30