<原著>ヒトにおけるREM睡眠時に特徴的な大脳皮質活動の先行的な出現

概要

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The purpose of the present study was to determine when in the transitional period from NREM sleep toREM sleep the cortical activity characterizing REM sleep begins to occur in man, using AEP with long latencyas an index. In 10 of 12 subjects examined, the amplitude of N300, a component of the cortical auditoryevoked potential, was evidently smaller in REM sleep than in non-REM sleep. The start of the reduction ofN300 associated with the onset of REM sleep was estimated in these 10 subjects. In 5 of them, a markedreduction of the N300 amplitude occurred 0.5 to 2.5 minute just preceding the appearance of muscle atonia ofREM sleep. In 2 subjects, a similarly marked reduction of the N300 amplitude occurred 0.5 to 1.0 minute justpreceding the disappearance of sleep spindles or K-complexes. The present results suggest that thephysiological phenomena characterizing REM sleep do not always begin simultaneously, and that in man, thebrain electrical activity characterizing REM sleep often occurs a few minutes or less prior to the other twophysiological phenomena characterizing REM sleep, muscle atonia and rapid eye movements.
秋田大学の論文