Mechanism-based Therapy for Leukemia: A Lesson from Atra Therapy
スポンサーリンク
概要
著者
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NAOE Tomoki
Department of Hematology and Oncology, Nagoya University Graduate School of Medicine
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Naoe Tomoki
大垣市民病院 血液内科
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Naoe T
Department Of Hematology And Oncology Nagoya University Graduate School Of Medicine
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Naoe Tomoki
Department Of Hematologly And Oncology Nagoya University School Of Medicine
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Naoe Tomoki
Department Of Infectious Diseases Nagoya University Graduate School Of Medicine
関連論文
- Randomized trial of response-oriented individualized versus fixed-schedule induction chemotherapy with idarubicin and cytarabine in adult acute myeloid leukemia : the JALSG AML95 study
- Comparative analysis of remission induction therapy for high-risk MDS and AML progressed from MDS in the MDS200 study of Japan Adult Leukemia Study Group
- Promoter Hypermethylation of the DNA-Repair Gene O^6-Methylguanine-DNA Methyltransferase and p53 Mutation in Diffuse Large B-Cell Lymphoma
- Loss of O^6-Methylguanine-DNA Methyltransferase Protein Expression Is a Favorable Prognostic Marker in Diffuse Large B-Cell Lymphoma
- PE-406 Relation of Body Mass Index to the Recurrence of Atrial Fibrillation after Pulmonary Vein Isolation via Radio Frequency Catheter Ablation(Diabetes/Obesity/Metabolic syndrome(07)(H),Poster Session(English),The 72nd Annual Scientific Meeting of the J
- Management of infection in patients with acute leukemia during chemotherapy in Japan : questionnaire analysis by the Japan Adult Leukemia Study Group
- A Phase I/II study of nilotinib in Japanese patients with imatinib-resistant or -intolerant Ph+ CML or relapsed/refractory Ph+ ALL
- Phase 1/2 clinical study of dasatinib in Japanese patients with chronic myeloid leukemia or Philadelphia chromosome-positive acute lymphoblastic leukemia
- Donor cell leukemia after allogeneic peripheral blood stem cell transplantation : a case report and literature review
- Vagal Modification Can Also Help Prevent Late Recurrence of Atrial Fibrillation After Segmental Pulmonary Vein Isolation
- PJ-511 Preoperative eGFR and LVdP/dtmax Predict the Long-term Effectiveness of Cardiac Resynchronization Therapy(PJ086,Heart Failure (Treatment) 2 (M),Poster Session (Japanese),The 73rd Annual Scientific Meeting of The Japanese Circulation Society)
- PJ-088 Optimization of Interventricular Delay in Cardiac Resynchronization Therapy Using Maximam LV dp/dt(PJ015,ICD (M),Poster Session (Japanese),The 73rd Annual Scientific Meeting of The Japanese Circulation Society)
- PJ-002 Relationship between Foci of Arrhythmia and Low Voltage Zone Depicted by Dynamic Substrate Map in Patients with RVOT VPC(PJ001,Arrhythmia, Others (Clinical/Pathophysiology) 1 (A),Poster Session (Japanese),The 73rd Annual Scientific Meeting of The J
- PJ-784 The Greater Efficacy of Extensive Encircling Pulmonary Vein Isolation for Persistent Atrial Fibrillation Than Individual Pulmonary Vein Antrum Isolation(Arrhythmia, therapy(17)(A),Poster Session(Japanese),The 72nd Annual Scientific Meeting of the J
- PJ-783 Catheter ablation for atrial fibrillation targeting atrial areas showing complex fractionated atrial electrogram after extensive ipsilateral pulmonary vein isolation(Arrhythmia, therapy(17)(A),Poster Session(Japanese),The 72nd Annual Scientific Mee
- PJ-695 Optimizing VV Delay by Three-Dimentional Echocardiography(Heart failure, clinical(19)(M),Poster Session(Japanese),The 72nd Annual Scientific Meeting of the Japanese Circulation Society)
- PJ-599 Efficacy of Pulmonary Vein Isolation in Patients with Bradycardia-Tachycardia Syndrome(Arrhythmia, therapy(16)(A),Poster Session(Japanese),The 72nd Annual Scientific Meeting of the Japanese Circulation Society)
- PJ-394 Sleep Apnea Syndrome May Play a Role in the Higher Incidence of Non-Pulmonary Vein Ectopic Beats Initiating Atrial Fibrillation(Arrhythmia, diagnosis/Pathophysiology/EPS(14)(A),Poster Session(Japanese),The 72nd Annual Scientific Meeting of the Japa
- PJ-316 Acute Hemodynamic Effects of V-V Delay Optimization in Cardiac Resynchronization Therapy(Heart failure, clinical(15)(M),Poster Session(Japanese),The 72nd Annual Scientific Meeting of the Japanese Circulation Society)
- PJ-315 Absolute Value of LVdP/dtmax during Intrinsic Rhythm and CRT at Baseline Predict the Long-term Effectiveness of CRT(Heart failure, clinical(15)(M),Poster Session(Japanese),The 72nd Annual Scientific Meeting of the Japanese Circulation Society)
- PJ-314 Longterm Outcome of CRT in Aged Patients with Heart Failure and IVCD(Heart failure, clinical(15)(M),Poster Session(Japanese),The 72nd Annual Scientific Meeting of the Japanese Circulation Society)
- PJ-284 Behavior of Atrial Premature Beats Triggering the Recurrences of Atrial Fibrillation After Pulmonary Vein Isolation(ECG/Body surface potential mapping/Holter(05)(A),Poster Session(Japanese),The 72nd Annual Scientific Meeting of the Japanese Circula
- PJ-221 Should Combined Resynchronization and Defibrillator Therapy be Indicated in All Japanese CRT Candidates without Ventricular Arrhythmias?(Arrhythmia, therapy(24)(A),Poster Session(Japanese),The 72nd Annual Scientific Meeting of the Japanese Circulat
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- The clinical characteristics of CD7^+ CD56^+ acute myeloid leukemias other than M0
- Definite diagnosis in Japanese patients with protein C deficiency by identification of causative PROC mutations
- Phase I/II study of humanized anti-CD33 antibody conjugated with calicheamicin, gemtuzumab ozogamicin, in relapsed or refractory acute myeloid leukemia : final results of Japanese multicenter cooperative study
- Retention but significant reduction of BCR-ABL transcript in hematopoietic stem cells in chronic myelogenous leukemia after imatinib therapy
- Mutational analysis of SOS1 gene in acute myeloid leukemia
- Clinical significance of minimal residual disease in patients with t(8;21) acute myeloid leukemia in Japan
- Evaluation of organ involvement in intravascular large B-cell lymphoma by ^F-fluorodeoxyglucose positron emission tomography
- Identification of amino acid residues responsible for von Willebrand factor binding to sulfatide by charged-to-alanine-scanning mutagenesis
- Sustained Remission after Rituximab-containing Chemotherapy for Intravascular Large B-cell Lymphoma
- Hematopoietic stem cell transplantation for acute promyelocytic leukemia in second or third complete remission : a retrospective analysis in the Nagoya Blood and Marrow Transplantation Group
- Diagnosis of acute myeloid leukemia according to the WHO classification in the Japan Adult Leukemia Study Group AML-97 protocol
- Wilms' tumor 1 message and protein expression in bone marrow failure syndrome and acute leukemia
- Epigenetic Regulation of CD20 Protein Expression in a Novel B-Cell Lymphoma Cell Line, RRBL1, Established from a Patient Treated Repeatedly with Rituximab-Containing Chemotherapy
- BMI-1 Is Highly Expressed in M0-Subtype Acute Myeloid Leukemia
- Successful Treatment with Imatinib Mesylate of a CML Patient in Megakaryoblastic Crisis with Severe Fibrosis
- Comparison of leukopenia between cytarabine and behenoyl cytarabine in JALSG AML-89 consolidation therapy
- Safety and Efficacy of Autologous Progenitor Cell Transplantation for Therapeutic Angiogenesis in Patients With Critical Limb Ischemia
- Downregulation of microRNAs-143 and -145 in B-cell malignancies
- let-7 MicroRNA Functions as a Potential Growth Suppressor in Human Colon Cancer Cells(Molecular and Cell Biology)
- A Case of Interstitial Pneumonia Induced by Rituximab Therapy
- Infectious complications during remission induction therapy in 577 patients with acute myeloid leukemia in the Japan Adult Leukemia Study Group studies between 1987 and 1991
- Chemical Speciation of Arsenic Species in Human Blood Serum by Liquid Chromatography Using a Phosphatidylcholine-Coated ODS Column with Detection by ICP-MS
- Central nervous system involvement in intravascular large B-cell lymphoma : A retrospective analysis of 109 patients
- Establishment of a Stroma-Dependent Human Acute Myelomonocytic Leukemia Cell Line, NAMO-2, with FLT3 Tandem Duplication
- Recurrent Intramural Hematoma of the Small Intestine in a Severe Hemophilia A Patient with a High Titer of Factor VIII Inhibitor : A Case Report and Review of the Literature
- High Titer of ADAMTS13 Inhibitor Associated with Thrombotic Microangiopathy of the Gut and Skeletal Muscle after Allogeneic Hematopoietic Stem Cell Transplantation
- Apoptotic Cytotoxic Effects of a Histone Deacetylase Inhibitor, FK228, on Malignant Lymphoid Cells
- Interaction of von Willebrand Factor with the Extracellular Matrix and Glycocalicin under Static Conditions^1
- Recent advances in the treatment of Philadelphia chromosome-positive acute lymphoblastic leukemia
- Spontaneous regression of aleukemic leukemia cutis harboring a NPM/RARA fusion gene in an infant with cutaneous mastosytosis
- Biology, Clinical Relevance, and Molecularly Targeted Therapy in Acute Leukemia with FLT3 Mutation
- Nucleophosmin : A versatile molecule associated with hematological malignancies
- Mechanism-based Therapy for Leukemia: A Lesson from Atra Therapy
- Karyotypically independent clones with del(11q) and trisomy 10 in acute myeloid leukemia : trisomy 10 may appear as an additional change
- Antitumor effect of arsenic trioxide in murine xenograft model
- Decreased risk of acute graft-versus-host disease following allogeneic hematopoietic stem cell transplantation in patients with the 5,10-methylenetetrahydrofolate reductase 677TT genotype
- Stable Engraftment after a Conditioning Regimen with Fludarabine and Melphalan for Bone Marrow Transplantation from an Unrelated Donor
- Quality of Life in Adult Patients after Bone Marrow Transplantation
- Irrespective of CD34 expression, lineage-committed cell fraction reconstitutes and re-establishes transformed Philadelphia chromosome-positive leukemia in NOD/SCID/IL-2Rγc^ mice
- Severe hemophilia A in a Japanese female caused by an F8-intron 22 inversion associated with skewed X chromosome inactivation
- Classic Polyarteritis Nodosa Presenting Rare Clinical Manifestations in a Patient with Hemophilia A
- Ectopic Expression of MAFB Gene in Human Myeloma Cells Carrying (14;20)(q32;q11) Chromosomal Translocations
- Acute myeloid leukemia in the elderly : 159 Nagoya case studies
- Sustained activation of c-jun-N-terminal kinase plays a critical role in arsenic trioxide-induced cell apoptosis in multiple myeloma cell lines
- Toxic effects of arsenic (As^) and other metal ions on acute promelocytic leukemia cells
- Immunoglobulin Variable Region Structure and B-Cell Malignancies
- Feasibility of salvage chemotherapy for refractory or relapsed non-Hodgkin's lymphoma with two topoisomerase II inhibitors, MST-16 and VP-16
- Immunoaffinity Purification and Characterization of CACGTG Sequence-Binding Proteins from Cultured Mammalian Cells Using an Anti c-Myc Monoclonal Antibody Recognizing the DNA-Binding Domain
- Intensified consolidation therapy with dose-escalated doxorubicin did not improve the prognosis of adults with acute lymphoblastic leukemia : the JALSG-ALL97 study
- Expanded distribution of the T315I mutation among hematopoietic stem cells and progenitors in a chronic myeloid leukemia patient during imatinib treatment
- Selective KIT inhibitor KI-328 and HSP90 inhibitor show different potency against the type of KIT mutations recurrently identified in acute myeloid leukemia
- Trough plasma concentration of imatinib reflects BCR-ABL kinase inhibitory activity and clinical response in chronic-phase chronic myeloid leukemia : A report from the BINGO study
- Virus-Associated Hemophagocytic Syndrome Caused by Pandemic Swine-Origin Influenza A (H1N1) in a Patient After Unrelated Bone Marrow Transplantation
- Phase I trial of gemtuzumab ozogamicin in intensive combination chemotherapy for relapsed or refractory adult acute myeloid leukemia (AML) : Japan Adult Leukemia Study Group (JALSG)-AML206 study
- Micafungin, a Novel Antifungal Agent, as Empirical Therapy in Acute Leukemia Patients with Febrile Neutropenia
- Analysis of bacteremia/fungemia and pneumonia accompanying acute myelogenous leukemia from 1987 to 2001 in the Japan Adult Leukemia Study Group
- A novel insertion mutation of K294RGG within BCR-ABL kinase domain confers imatinib resistance : sequential analysis of the clonal evolution in a patient with chronic myeloid leukemia in blast crisis
- Efficacy and safety of nilotinib in Japanese patients with imatinib-resistant or -intolerant Ph+ CML or relapsed/refractory Ph+ ALL : a 36-month analysis of a phase I and II study
- Dexamethasone palmitate successfully attenuates hemophagocytic syndrome after allogeneic stem cell transplantation : macrophage-targeted steroid therapy
- Mutation of ARHGAP9 in patients with coronary spastic angina
- Randomized comparison of fixed-schedule versus response-oriented individualized induction therapy and use of ubenimex during and after consolidation therapy for elderly patients with acute myeloid leukemia : the JALSG GML200 Study
- Acute myeloid leukemia in older adults
- Efficacy and safety of human adipose tissue-derived mesenchymal stem cells for supporting hematopoiesis
- Phase 1 trial of gemtuzumab ozogamicin in combination with enocitabine and daunorubicin for elderly patients with relapsed or refractory acute myeloid leukemia : Japan Adult Leukemia Study Group (JALSG)-GML208 study
- Development of Adult T-cell Leukemia in a Patient with Rheumatoid Arthritis Treated with Tocilizumab
- Guest editorial : Introducing progress in hematology in this issue
- Iron chelation therapy for a case of transfusion-independent MDS-RARS with significant iron overload
- Interaction of von Willebrand Factor with the Extracellular Matrix and Glycocalicin under Static Conditions.
- Immunoaffinity Purification and Characterization of CACGTG Sequence-Binding Proteins from Cultured Mammalian Cells Using an Anti c-Myc Monoclonal Antibody Recognizing the DNA-Binding Domain.
- Gene mutations of acute myeloid leukemia in the genome era
- Micafungin for empirical antifungal therapy in patients with febrile neutropenia: multicenter phase 2 study