Phase 1 trial of gemtuzumab ozogamicin in combination with enocitabine and daunorubicin for elderly patients with relapsed or refractory acute myeloid leukemia : Japan Adult Leukemia Study Group (JALSG)-GML208 study

スポンサーリンク

概要

• 論文の詳細を見る
• 2012-10-01

著者

• Gotoh Moritaka

  Division Of Hematology Tokyo Medical University

• Naoe Tomoki

  Department Of Hematologly And Oncology Nagoya University School Of Medicine

• Ohyashiki Kazuma

  Division Of Hematology Tokyo Medical University

• ITO Yoshikazu

  Division of Hematology, First Department of Internal Medicine, Tokyo Medical University

• Ito Yoshikazu

  Division Of Hematology First Department Of Internal Medicine Tokyo Medical University

• Wakita Atsushi

  Department Of Internal Medicine And Molecular Science Nagoya City University Graduate School Of Medi

• MIYAWAKI Shuichi

  Hematology Division, Tokyo Metropolitan Ohtsuka Hospital

• Takada Satoru

  Leukemia Research Center Saiseikai Maebashi Hospital

• Ohtake Shigeki

  Department Of Clinical Laboratory Science Kanazawa University Graduate School Kanazawa University

• Ohnishi Kazunori

  Department Of Cell Pathology Graduate School Of Medical Sciences Kumamoto University

• OHTAKE Shigeki

  Department of Clinical Laboratory Science, Kanazawa University Graduate School of Medical Science

• OHYASHIKI Kazuma

  Division of Hematology, First Department of Internal Medicine, Tokyo Medical University

• OHNISHI Kazunori

  Department of Internal Medicine 3, Oncology Center, Hamamatsu University School of Medicine

• MIHARA Masahiro

  Division of Hematology, Fujioka General Hospital

• GOTOH Moritaka

  Division of Hematology, First Department of Internal Medicine, Tokyo Medical University

• WAKITA Atsushi

  Department of Hematology and Oncology, Nagoya City West Medical Center

関連論文

• Allogeneic stem cell transplantation versus chemotherapy as post-remission therapy for intermediate or poor risk adult acute myeloid leukemia : results of the JALSG AML97 study
• Randomized trial of response-oriented individualized versus fixed-schedule induction chemotherapy with idarubicin and cytarabine in adult acute myeloid leukemia : the JALSG AML95 study
• Comparative analysis of remission induction therapy for high-risk MDS and AML progressed from MDS in the MDS200 study of Japan Adult Leukemia Study Group
• Increased macrophage colony-stimulating factor levels in patients with Graves' disease
• Promoter Hypermethylation of the DNA-Repair Gene O^6-Methylguanine-DNA Methyltransferase and p53 Mutation in Diffuse Large B-Cell Lymphoma
• Loss of O^6-Methylguanine-DNA Methyltransferase Protein Expression Is a Favorable Prognostic Marker in Diffuse Large B-Cell Lymphoma
• Prognostic analysis and a new risk model for Hodgkin lymphoma in Japan
• Donor cell leukemia after allogeneic peripheral blood stem cell transplantation : a case report and literature review
• Prediction of Sensitivity to STI571 among Chronic Myeloid Leukemia Patients by Genome-wide cDNA Microarray Analysis
• The clinical characteristics of CD7^+ CD56^+ acute myeloid leukemias other than M0
• Definite diagnosis in Japanese patients with protein C deficiency by identification of causative PROC mutations
• Phase I/II study of humanized anti-CD33 antibody conjugated with calicheamicin, gemtuzumab ozogamicin, in relapsed or refractory acute myeloid leukemia : final results of Japanese multicenter cooperative study
• Retention but significant reduction of BCR-ABL transcript in hematopoietic stem cells in chronic myelogenous leukemia after imatinib therapy
• Mutational analysis of SOS1 gene in acute myeloid leukemia
• Clinical significance of minimal residual disease in patients with t(8;21) acute myeloid leukemia in Japan
• Evaluation of organ involvement in intravascular large B-cell lymphoma by ^F-fluorodeoxyglucose positron emission tomography
• Identification of amino acid residues responsible for von Willebrand factor binding to sulfatide by charged-to-alanine-scanning mutagenesis
• Sustained Remission after Rituximab-containing Chemotherapy for Intravascular Large B-cell Lymphoma
• Hematopoietic stem cell transplantation for acute promyelocytic leukemia in second or third complete remission : a retrospective analysis in the Nagoya Blood and Marrow Transplantation Group
• Diagnosis of acute myeloid leukemia according to the WHO classification in the Japan Adult Leukemia Study Group AML-97 protocol
• Wilms' tumor 1 message and protein expression in bone marrow failure syndrome and acute leukemia
• Epigenetic Regulation of CD20 Protein Expression in a Novel B-Cell Lymphoma Cell Line, RRBL1, Established from a Patient Treated Repeatedly with Rituximab-Containing Chemotherapy
• BMI-1 Is Highly Expressed in M0-Subtype Acute Myeloid Leukemia
• Successful Treatment with Imatinib Mesylate of a CML Patient in Megakaryoblastic Crisis with Severe Fibrosis
• Comparison of leukopenia between cytarabine and behenoyl cytarabine in JALSG AML-89 consolidation therapy
• No beneficial effect from addition of etoposide to daunorubicin,cytarabine,and 6-mercaptopurine in individualized induction therapy of adult acute myeloid leukemia:the JALSG-AML92 study
• Safety and Efficacy of Autologous Progenitor Cell Transplantation for Therapeutic Angiogenesis in Patients With Critical Limb Ischemia
• Downregulation of microRNAs-143 and -145 in B-cell malignancies
• let-7 MicroRNA Functions as a Potential Growth Suppressor in Human Colon Cancer Cells(Molecular and Cell Biology)
• A Case of Interstitial Pneumonia Induced by Rituximab Therapy
• Infectious complications during remission induction therapy in 577 patients with acute myeloid leukemia in the Japan Adult Leukemia Study Group studies between 1987 and 1991
• Chemical Speciation of Arsenic Species in Human Blood Serum by Liquid Chromatography Using a Phosphatidylcholine-Coated ODS Column with Detection by ICP-MS
• Multicenter Prospective Study of Interferon-α and Conventional Chemotherapy Versus Bone Marrow Transplantation for Newly Diagnosed Patients With Chronic Myelogenous Leukemia
• Central nervous system involvement in intravascular large B-cell lymphoma : A retrospective analysis of 109 patients
• Establishment of a Stroma-Dependent Human Acute Myelomonocytic Leukemia Cell Line, NAMO-2, with FLT3 Tandem Duplication
• Recurrent Intramural Hematoma of the Small Intestine in a Severe Hemophilia A Patient with a High Titer of Factor VIII Inhibitor : A Case Report and Review of the Literature
• High Titer of ADAMTS13 Inhibitor Associated with Thrombotic Microangiopathy of the Gut and Skeletal Muscle after Allogeneic Hematopoietic Stem Cell Transplantation
• Apoptotic Cytotoxic Effects of a Histone Deacetylase Inhibitor, FK228, on Malignant Lymphoid Cells
• Living-donor lobar lung transplantation for broncho-bronchiolitis obliterans after allogeneic hematopoietic stem cell transplantation: does bronchiolitis obliterans recur in transplanted lungs?
• Refractory Crow-Fukase Syndrome (POEMS Syndrome) Successfully Treated with High-Dose Melphalan followed by Autologous Peripheral Blood Stem Cell Transplantation
• Interaction of von Willebrand Factor with the Extracellular Matrix and Glycocalicin under Static Conditions^1
• Treatment of acute myeloid leukemia and myelodysplastic syndrome with orally administered cytarabine ocfosfate and granulocyte colony-stimulating factor
• Restoration of cardiac function by an iron chelator, deferasirox, in a patient with aplastic anemia and cardiac iron overload
• Recent advances in the treatment of Philadelphia chromosome-positive acute lymphoblastic leukemia
• Myeloid/Natural Killer Cell Precursor Acute Leukemia Accompanied by Homozygous Protein C Deficiency
• Can Eradication Therapy for Helicobacter pylori Really Inprove the Thrombocytopenia in Idiopathic Thrombocytopenic Purpura? Our Experience and a Literature Review
• Thrombocytopenia Induced by Imatinib Mesylate(Glivec) in Patients with Chronic Myelogenous Leukemia : Is 400 mg Daily of Imatinib Mesylate an Optimal Starting Dose for Japanese Patients?
• Spontaneous regression of aleukemic leukemia cutis harboring a NPM/RARA fusion gene in an infant with cutaneous mastosytosis
• All-trans-retinoic acid as a possible cause of acute pancreatitis even in the absence of hypertriglyceridemia
• Biology, Clinical Relevance, and Molecularly Targeted Therapy in Acute Leukemia with FLT3 Mutation
• Nucleophosmin : A versatile molecule associated with hematological malignancies
• Mechanism-based Therapy for Leukemia: A Lesson from Atra Therapy
• Karyotypically independent clones with del(11q) and trisomy 10 in acute myeloid leukemia : trisomy 10 may appear as an additional change
• Antitumor effect of arsenic trioxide in murine xenograft model
• Decreased risk of acute graft-versus-host disease following allogeneic hematopoietic stem cell transplantation in patients with the 5,10-methylenetetrahydrofolate reductase 677TT genotype
• Stable Engraftment after a Conditioning Regimen with Fludarabine and Melphalan for Bone Marrow Transplantation from an Unrelated Donor
• Quality of Life in Adult Patients after Bone Marrow Transplantation
• Irrespective of CD34 expression, lineage-committed cell fraction reconstitutes and re-establishes transformed Philadelphia chromosome-positive leukemia in NOD/SCID/IL-2Rγc^ mice
• Twenty Years' Experience in Allogeneic Hematopoietic Stem Cell Transplantation for Philadelphia Chromosome-Positive Acute Lymphoblastic Leukemia in the Nagoya Blood and Marrow Transplantation Group
• Severe hemophilia A in a Japanese female caused by an F8-intron 22 inversion associated with skewed X chromosome inactivation
• Classic Polyarteritis Nodosa Presenting Rare Clinical Manifestations in a Patient with Hemophilia A
• Superior Mesenteric Venous Thrombosis Associated With a Familial Missense Mutation (Pro626Leu) in the SHBG-Like Domain of the Protein S Molecule
• Ectopic Expression of MAFB Gene in Human Myeloma Cells Carrying (14;20)(q32;q11) Chromosomal Translocations
• Acute myeloid leukemia in the elderly : 159 Nagoya case studies
• Leukocytosis is linked to thrombosis at diagnosis, while JAK2 V617F mutation is associated with thrombosis during the course of essential thrombocythemia
• The Prophylactic Effect of Itraconazole Capsules and Fluconazole Capsules for Systemic Fungal Infections in Patients with Acute Myeloid Leukemia and Myelodysplastic Syndromes : A Japanese Multicenter Randomized, Controlled Study
• Sustained activation of c-jun-N-terminal kinase plays a critical role in arsenic trioxide-induced cell apoptosis in multiple myeloma cell lines
• Clonality Assay of Hematopoietic Disorders: Significance of the Buccal Epithelium as Non-hematopoietic Control and of 95% Rejection Limit as a Novel Criterion for Monoclonality
• Toxic effects of arsenic (As^) and other metal ions on acute promelocytic leukemia cells
• Immunoglobulin Variable Region Structure and B-Cell Malignancies
• Relapse of chronic myeloid leukemia-chronic phase 14 years after allogeneic hematopoietic stem cell transplantation
• Feasibility of salvage chemotherapy for refractory or relapsed non-Hodgkin's lymphoma with two topoisomerase II inhibitors, MST-16 and VP-16
• Immunoaffinity Purification and Characterization of CACGTG Sequence-Binding Proteins from Cultured Mammalian Cells Using an Anti c-Myc Monoclonal Antibody Recognizing the DNA-Binding Domain
• Intensified consolidation therapy with dose-escalated doxorubicin did not improve the prognosis of adults with acute lymphoblastic leukemia : the JALSG-ALL97 study
• Expanded distribution of the T315I mutation among hematopoietic stem cells and progenitors in a chronic myeloid leukemia patient during imatinib treatment
• Estimation of cardiac left ventricular ejection fraction in transfusional cardiac iron overload by R2^* magnetic resonance
• Selective KIT inhibitor KI-328 and HSP90 inhibitor show different potency against the type of KIT mutations recurrently identified in acute myeloid leukemia
• Trough plasma concentration of imatinib reflects BCR-ABL kinase inhibitory activity and clinical response in chronic-phase chronic myeloid leukemia : A report from the BINGO study
• Virus-Associated Hemophagocytic Syndrome Caused by Pandemic Swine-Origin Influenza A (H1N1) in a Patient After Unrelated Bone Marrow Transplantation
• Phase I trial of gemtuzumab ozogamicin in intensive combination chemotherapy for relapsed or refractory adult acute myeloid leukemia (AML) : Japan Adult Leukemia Study Group (JALSG)-AML206 study
• Micafungin, a Novel Antifungal Agent, as Empirical Therapy in Acute Leukemia Patients with Febrile Neutropenia
• Analysis of bacteremia/fungemia and pneumonia accompanying acute myelogenous leukemia from 1987 to 2001 in the Japan Adult Leukemia Study Group
• Two case reports of inherited antithrombin deficiency : a novel frameshift mutation and a large deletion including all seven exons detected using two methods
• A novel insertion mutation of K294RGG within BCR-ABL kinase domain confers imatinib resistance : sequential analysis of the clonal evolution in a patient with chronic myeloid leukemia in blast crisis
• Dexamethasone palmitate successfully attenuates hemophagocytic syndrome after allogeneic stem cell transplantation : macrophage-targeted steroid therapy
• Mutation of ARHGAP9 in patients with coronary spastic angina
• Randomized comparison of fixed-schedule versus response-oriented individualized induction therapy and use of ubenimex during and after consolidation therapy for elderly patients with acute myeloid leukemia : the JALSG GML200 Study
• Acute myeloid leukemia in older adults
• Late response to low-dose imatinib in patients with chronic phase chronic myeloid leukemia
• Efficacy and safety of human adipose tissue-derived mesenchymal stem cells for supporting hematopoiesis
• Phase 1 trial of gemtuzumab ozogamicin in combination with enocitabine and daunorubicin for elderly patients with relapsed or refractory acute myeloid leukemia : Japan Adult Leukemia Study Group (JALSG)-GML208 study
• Development of Adult T-cell Leukemia in a Patient with Rheumatoid Arthritis Treated with Tocilizumab
• Guest editorial : Introducing progress in hematology in this issue
• Iron chelation therapy for a case of transfusion-independent MDS-RARS with significant iron overload
• Interaction of von Willebrand Factor with the Extracellular Matrix and Glycocalicin under Static Conditions.
• Immunoaffinity Purification and Characterization of CACGTG Sequence-Binding Proteins from Cultured Mammalian Cells Using an Anti c-Myc Monoclonal Antibody Recognizing the DNA-Binding Domain.
• Gene mutations of acute myeloid leukemia in the genome era
• Clinical efficacy and safety of arbekacin sulfate in patients with MRSA sepsis or pneumonia : a multi-institutional study
• Persistence of anti-HLA antibody after cord blood transplantation engraftment in acute myelogenous leukemia : a potential marker of minimal residual disease, but not a significant factor in secondary humoral engraftment failure
• Micafungin for empirical antifungal therapy in patients with febrile neutropenia: multicenter phase 2 study

もっと見る 閉じる

スポンサーリンク