Efficient targeted mutagenesis of the chordate Ciona intestinalis genome with zinc-finger nucleases

スポンサーリンク

概要

• 論文の詳細を見る
• 2012-06-01

著者

• Sawada Hitoshi

  Sugashima Marine Biol. Lab. Nagoya Univ.

• Ochiai Hiroshi

  Department Of Biochemistry And Biotechnology Faculty Of Agriculture And Life Science Hirosaki Univer

• Sasakura Yasunori

  Shimoda Marine Research Center University Of Tsukuba

• Yamamoto Takashi

  Department Of Applied Chemistry Faculty Of Engineering Ehime University

• KAWAI Narudo

  Shimoda Marine Research Center, University of Tsukuba

• SAKUMA Tetsushi

  Department of Mathematical and Life Sciences, Graduate School of Science, Hiroshima University

• YAMADA Lixy

  Sugashima Marine Biological Laboratory, Graduate School of Science, Nagoya University

• YAMAMOTO Takashi

  Department of Mathematical and Life Sciences, Graduate School of Science, Hiroshima University

関連論文

• Comparison of the long-term effects of candesartan and olmesartan on plasma angiotensin II and left ventricular mass index in patients with hypertension
• Primary research on MGSAD023, a new homokogue of eIF4G
• Reactivity between Sn-Ag Solder and Au/Ni-Co Plating to Form Intermetallic Phases
• Bcl11b heterozygosity promotes clonal expansion and differentiation arrest of thymocytes in γ-irradiated mice
• PJ-314 Longterm Outcome of CRT in Aged Patients with Heart Failure and IVCD(Heart failure, clinical(15)(M),Poster Session(Japanese),The 72nd Annual Scientific Meeting of the Japanese Circulation Society)
• Organ-Specific and Age-Dependent Expression of Insulin-like Growth Factor-I(IGF-I) mRNA Variants : IGF-IA and IB mRNAs in the Mouse(Endocrinology)
• Egg and sperm recognition systems during fertilization
• PE-389 Left Atrium Reverse Remodeling after Pulmonary Vein Isolation : Will It be a Predictor for Non-recurrence of Atrial Fibrillation?(PE065,Atrial/Supraventricular Arrhythmia (Clinical/Treatment) 3 (A),Poster Session (English),The 73rd Annual Scientifi
• PJ-842 Detection of Coronary Artery Disease in Asymptomatic Patients with Type 2 Diabetes Mellitus(Diabetes / Obesity / Metabolic syndrome(15)(H),Poster Session(Japanese),The 72nd Annual Scientific Meeting of the Japanese Circulation Society)
• PJ-598 Pulmonary Vein Isolation for Atrial Fibrillation in Patients with Brady-Tachy Type Sick Sinus Syndrome(Arrhythmia, therapy(16)(A),Poster Session(Japanese),The 72nd Annual Scientific Meeting of the Japanese Circulation Society)
• PJ-184 Analysis of Late Stent Thrombosis(Thromboembolism/Antithrombotic therapy/Thrombolysis(04)(H),Poster Session(Japanese),The 72nd Annual Scientific Meeting of the Japanese Circulation Society)
• PJ-060 The Initial Clinical Outcomes of Mini-Crush Stenting for Left Main True Bifurcation Lesions.(Coronary revascularization, PCI(16)(IHD),Poster Session(Japanese),The 72nd Annual Scientific Meeting of the Japanese Circulation Society)
• OE-219 Role of Bradykinin and Chymase in Cardiorenal Function under Chronic ACE Inhibition in Heart Failure(OE37,Kidney/Renal Circulation/CKD 1 (H),Oral Presentation (English),The 73rd Annual Scientific Meeting of The Japanese Circulation Society)
• PJ-306 ACE and Chymase Inhibition Prevents the Cardiac Remodeling Process Interacting with Cardiac Endothelin System in Heart Failure.(Heart failure, basic(06)(M),Poster Session(Japanese),The 72nd Annual Scientific Meeting of the Japanese Circulation Soci
• Cardiac Mast Cell Chymase Plays a Significant Role in the Progression of Cardiac Remodeling via Collagen Accumulation(Inflammatory Heart Disease-Update and Future Perspective-, The 69th Annual Scientific Meeting of the Japanese Circulation Society)
• Domain Orientation Imaging of PbTiO_3 Single Crystalsby Vertical and Lateral Piezoresponse Force Microscopy
• Multidetector-Row Computed Tomography Coronary Angiography : Optimization of Image Reconstruction Phase According to the Heart Rate
• Particle-Size Dependence of Crystal Structure of BaTiO_3 Powder
• PJ-525 The Acute and Late Outcome of Sirolimus-eluting Stent(SES) in Small Coronary Arteries Comparing with Bare-Metal Stent(BMS)(Coronary revascularization, PCI-19 (IHD) PJ88,Poster Session (Japanese),The 70th Anniversary Annual Scientific Meeting of the
• PJ-519 Late Outcome of Drug Eluting Stent (DES) in the High Restenosis Factors in Bare Metal Stent (BMS) Era(Coronary revascularization, PCI-18 (IHD) PJ87,Poster Session (Japanese),The 70th Anniversary Annual Scientific Meeting of the Japanese Circulation
• PJ-358 8 Month-outcome of Very Long (>36mm) Silolimus-eluting-stent Implanted Segments(Coronary revascularization, PCI-16 (IHD) PJ61,Poster Session (Japanese),The 70th Anniversary Annual Scientific Meeting of the Japanese Circulation Society)
• PJ-134 Late Outcome of Sirolimus Eluting Stent in any Lesion Type of Diabetic Patients in Japan(Restenosis, basic/clinical-6 (IHD) PJ23,Poster Session (Japanese),The 70th Anniversary Annual Scientific Meeting of the Japanese Circulation Society)
• OE-417 Left Atrial Reverse Remodeling as a Predictor of Non-Reccurence after Pulmonary Vein Isolation in Persistent and Chronic Atrial Fibrillation Patients(OE70,Atrial Fibrillation/Supraventricular Arrhythmia: Diagnosis 1 (A),Oral Presentation (English),
• Intermediate Valence State of La_Eu_Ni_2(Si_Ge_x)_2 Compounds (Condensed Matter: Electronic Structure, Electrical, Magnetic and Optical Properties)
• Long-term effect of efonidipine therapy on plasma aldosterone and left ventricular mass index in patients with essential hypertension
• PJ-641 Comparison of Serum Levels of Cardiac Tropnin I and T in Patients with Chronic Heart Failure(PJ108,Heart Failure (Laboratory/Biomarkers) 1 (M),Poster Session (Japanese),The 73rd Annual Scientific Meeting of The Japanese Circulation Society)
• PJ-371 Effect of Carperitide on Plasma Adiponectin Level in Heart Failure Patients with Diabetes Mellitus(PJ063,Heart Failure (Treatment) 1 (M),Poster Session (Japanese),The 73rd Annual Scientific Meeting of The Japanese Circulation Society)
• Chotosan Enhances Macrophage Colony-Stimulating Factor mRNA Expression in the Ischemic Rat Brain and C6Bu-1 Glioma Cells(Biochemistry)
• The relationship between coronary artery calcification detected by non-gated multi-detector CT in patients with suspected ischemic heart disease and myocardial ischemia detected by thallium exercise stress testing
• OJ-245 Effect of Carvedilol on Plasma Adiponectin Level in Patients with Chronic Heart Failure(OJ41,Heart Failure (Treatment) (M),Oral Presentation (Japanese),The 73rd Annual Scientific Meeting of The Japanese Circulation Society)
• OJ-244 Effect of Carvedilol on Transcardiac Gradient of Norepinephrine and Prognosis in Patients with Chronic Heart Failure(OJ41,Heart Failure (Treatment) (M),Oral Presentation (Japanese),The 73rd Annual Scientific Meeting of The Japanese Circulation Soci
• Spectral Changes of Lysozyme Adsorbed on Ultrafine Silica Particles
• PJ-481 Impact of Diabetes Mellitus on Coronary Atherosclerosis in Patients with Zero Calcium Score Using 64-MDCT(PJ081,CT/MRI (Coronary/Vascular) 3 (I),Poster Session (Japanese),The 73rd Annual Scientific Meeting of The Japanese Circulation Society)
• PJ-136 Gender Differences in Outcomes after Primary Intervention for ST-segment Elevation Myocardial Infarction(PJ023,ACS/AMI (Clinical/Pathophysiology/Treatment/Basic) (IHD),Poster Session (Japanese),The 73rd Annual Scientific Meeting of The Japanese Cir
• PJ-135 Iron Deficiency is Associated with Lower eGFR, and Predicts Left Ventricular Dysfunction after Primary Intervention for ST-segment Elevation Myocardial Infarction(PJ023,ACS/AMI (Clinical/Pathophysiology/Treatment/Basic) (IHD),Poster Session (Japane
• PJ-054 Assessment of Coronary Atherosclerosis by 64-MDCT in Patients with Normal and Low Calcium Score(PJ009,CT/MRI (Coronary/Vascular) 4 (I),Poster Session (Japanese),The 73rd Annual Scientific Meeting of The Japanese Circulation Society)
• PJ-893 Anemia is Associated with Lower eGFR and Predicts Poor Outcome after Primary Angioplasty for ST-segment Elevation Myocardial Infarction(Kidney / Renal circulation(08)(H),Poster Session(Japanese),The 72nd Annual Scientific Meeting of the Japanese Ci
• PJ-892 Advanced Stages of Chronic Kidney Disease Predicts Poor Clinical Outcomes in Patients with Acute Myocardial Infarction after Percutaneous Coronary Intervention(Kidney / Renal circulation(08)(H),Poster Session(Japanese),The 72nd Annual Scientific Me
• PJ-382 Inpact of Elderly Patients on Outcome and Predictors for a Poor Prognosis with Acute Myocardial Infarction after Successful PCI(Acute myocardial infarction, clinical(diagnosis/treatment)(10)(IHD),Poster Session(Japanese),The 72nd Annual Scientific
• OJ-038 Chronic Kidney Disease with Diabetes Mellitus Predicts Poor Clinical Outcomes in Patients with Acute Myocardial Infarction after Percutaneous Coronary Intervention(Acute myocardial infarction, clinical(diagnosis/treatment)(03)(IHD),Oral Presentatio
• PJ-580 Early Administration of Fluvastatin Improves Left Ventricular Function in Normocholesterolemic Patients after Primary Angioplasty for Acute Myocardial Infarction(Acute myocardial infarction, clinical (diagnosis/treatment)-10 (IHD) PJ98,Poster Sessi
• PJ-444 Hyperglycemia on Admission Predicts Insulin Resistance and Poorer Clinical Outcomes in Patients with Acute Myocardial Infarction(Acute myocardial infarction, clinical (diagnosis/treatment)-9 (IHD) PJ75,Poster Session (Japanese),The 70th Anniversary
• High-normal Creatinine on Presentation Predicts Left Ventricular Dysfunction after Successful Percutaneous Coronary Intervention in Patients with Acute Myocardial Infarction(Acute Myocardial Infarction, Clinical (Diagnosis/Treatment) 5 (IHD), The 69th Ann
• PJ-518 Acute and Late Outcome of Sirolimus Eluting Stent in Bifurcation Lesions Comparing with Bare Metal Stent(Coronary revascularization, PCI-18 (IHD) PJ87,Poster Session (Japanese),The 70th Anniversary Annual Scientific Meeting of the Japanese Circulat
• Spin Dynamics in the Supersymmetric t-J Model with Inverse-Square Interaction (Condensed Matter : Electronic Structure, Electrical, Magnetic and Optical Properties)
• FRS-025 Comparison with Serum Cortisol Level and Plasma Aldosterone Level as a Predictor of Cardiac Event in Patients with Heart Failure(FRS5,Novel Biomarkers in Heart Failure (M),Featured Research Session (English),The 73rd Annual Scientific Meeting of T
• Beneficial Effect of Perindopril on Cardiac Sympathetic Nerve Activity and Brain Natriuretic Peptide in Patients With Chronic Heart Failure : Comparison With Enalapril
• PJ-512 Impact of Oxidative Stress on Plasma Adiponectin in Patients with Heart Failure(Heart failure, clinical(18)(M),Poster Session(Japanese),The 72nd Annual Scientific Meeting of the Japanese Circulation Society)
• Comparison of the Effects of Efonidipine and Amlodipine on Aldosterone in Patients with Hypertension
• In-situ observation of a MEMS-based Pb(Zr,Ti)O3 micro cantilever using micro-Raman spectroscopy
• Novel-Type Charge-Transfer Complex Formation between Indoxyl Sulfate and Anthraquinonesulfonate Ions in an Aqueous Polyelectrolyte Solution
• Unichrom, a Novel Nuclear Matrix Protein, Binds to the Ars Insulator and Canonical MARs(Biochemistry)
• SKELETOGENIC CELLS FORMING ADULT SEA URCHIN SPICULES(Developmental Biology,Abstracts of papers presented at the 76^ Annual Meeting of the Zoological Society of Japan)
• TRANSCRIPTIONAL REGULATION OF THE HpTb GENE DURING SEA URCHIN (HEMICENTROTUS PURCHERRIMUS) DEVELOPMENT(Developmental Biology,Abstracts of papers presented at the 76^ Annual Meeting of the Zoological Society of Japan)
• A new G-stretch-DNA-binding protein, Unichrom, displays cell-cycle-dependent expression in sea urchin embryos
• The Otx binding site is required for the activation of HpOtxL mRNA expression in the sea urchin, Hemicentrotus pulcherrimus
• THE MINIMAL REGULATORY REGION FOR THE MICROMERE DESCENDANT CELL SPECIFIC HpEts EXPRESSION IN SEA URCHIN EMBRYO(Developmental Biology,Abstracts of papers presented at the 74^ Annual Meeting of the Zoological Society of Japan)
• TRANSCRIPTIONAL REGULATION OF THE HpOtxL GENE DURING SEA URCHIN (HEMICENTROTUS PURCHERRIMUS) DEVELOPMENT(Developmental Biology,Abstracts of papers presented at the 74^ Annual Meeting of the Zoological Society of Japan)
• A SEA URCHIN HEMICENTROTUS PULCHERRIMUS HOMOLOGUE HpSu(H) IS INVOLVED IN THE DIFFERENTIATION OF SECONDARY MESENCHYME CELLS(Developmental Biology,Abstracts of papers presented at the 74^ Annual Meeting of the Zoological Society of Japan)
• TRANSCRIPTIONAL REGULATION OF THE OTX GENE DURING SEA URCHIN (HEMICENTROTUS PURCHERRIMUS) DEVELOPMENT(Developmental Biology)(Proceedings of the Seventy-Third Annual Meeting of the Zoological Society of Japan)
• Dynamic Viscoelastic Properties of Multi-Arm Star Polystyrenes in the Molten State
• Longitudinal Myocardial Displacement and Strain Rate in Hypertrophied Heart Evaluated by Tissue Strain Imaging with Doppler Tissue Tracking Technique
• Quantitative Assessment of Left Ventricular Myocardial Viability during Low Dose Dobutamine Stress Echocardiography in Combination with Color Tissue Doppler Imaging
• Better Choice of Color Tissue Doppler Imaging Coupled with High Dose Dobutamine Stress Echocardiography for Detecting Coronary Artery Stenosis
• Impact of Losartan on Left Ventricular Myocardial Function in Hypertensive Hypertrophy : Assessment of Myocardial Velocity Profile and Plasma Vasoactive Peptide
• Proteome Analysis Reveals the Significant Alternations of Cardiac Small Heat Shock Proteins Expression in Heart Failure (Heart Failure, Basic 6 (M), The 69th Annual Scientific Meeting of the Japanese Circulation Society)
• Chronic NADPH Oxidase Inhibiton Improves Cardiac Function through the Suppression of Oxidative Stress in Heart Failure(Cardiovascular Pharmacology, Basic/Clinical 2 (H), The 69th Annual Scientific Meeting of the Japanese Circulation Society)
• PJ-224 The Activity and Expression of Myocardial NADPH Oxidase Are Increased in Heart Failure.(Heart Failure, Basic 2 (M) : PJ38)(Poster Session (Japanese))
• GENOMIC ANALYSIS AND MOLECULAR EVOLUTION OF THE VITELLINE COAT PROTEIN, HaVC80, IN THE ASCIDIAN, HALOCYNTHIA AURANTIUM(Developmental Biology,Abstracts of papers presented at the 75^ Annual Meeting of the Zoological Society of Japan)
• Induction of Inducible Nitric Oxide (NO) Synthase mRNA and NO Production in Macrophages Infected with Influenza A/PR/8 Virus and Stimulated with Its Ether-Split Product
• A case-control study of purple urine bag syndrome in geriatric wards
• SUGAR CHAIN STRUCTURE OF SPERM RECEPTOR HrVC70 ON THE VITELLINE COAT IN THE ASCIDIAN HALOCYNTHIA RORETZI(Developmental Biology,Abstracts of papers presented at the 76^ Annual Meeting of the Zoological Society of Japan)
• THE SIGNIFICANCE OF ENVIRONMENTAL EDUCATION AS EVIDENCED BY EVALUATION OF A MODULE FOR SCIENCE TEACHER TRAINING PROGRAMS
• THE STATUS OF ENVIRONMENTAL CHEMISTRY EDUCATION IN SECONDARY SCHOOLS IN KOREA : A COMPARATIVE STUDY BETWEEN KOREA AND JAPAN
• Charge-Transfer Complexation in an Aqueous Polyelectrolyte Solution. III. Complexation between Pyrenesulfonate or Anthracenesulfonate and Anthraquinonesulfonate Ions
• Effects of Polyelectrolytes on the Complexation between Pyrenesulfonate and Anthraquinonesulfonate Ions
• An Investigation of the Conformation of β-Carrageenan by Molecular Mechanics and Molecular Dynamics Simulations
• An Investigation of the Ionic Polarization of Carrageenans with Different Charge Densities
• An Observation of the Electric Birefringence Signal of k-Carrageenan Gel
• Mechanisms of Self-Nonself Recognition and Lysin System in Ascidian Fertilization(Symposium on Molecular Mechanism of Gametogenesis and Fertilization: Its Biological Significance and Advanced Technology,PROCEEDING OF THE 74^ ANNUAL MEETING OF THE ZOOL
• A GENETIC ANALYSIS ON THE MECHANISM OF SELF-STERILITY IN CIONA INTESTJNALIS(Developmental Biology,Abstracts of papers presented at the 75^ Annual Meeting of the Zoological Society of Japan)
• The Mechanism of Bone Resorption Induced by Epiregulin, a Member of EGF Family(International Symposium of Maxillofacial and Oral Regenerative Biology in Okayama 2005)
• IDENTIFICATION OF SPERM LIGAND HUURABIN FOR SPERM RECEPTOR HrVC70 IN THE ASCIDIAN HALOCYNTHIA RORETZI(Developmental Biology,Abstracts of papers presented at the 76^ Annual Meeting of the Zoological Society of Japan)
• YEAST TWO-HYBRID SCREENING FOR MOLECULES THAT INTERACT WITH ASCIDIAN SPERM RECEPTOR HrVC70(Developmental Biology,Abstracts of papers presented at the 76^ Annual Meeting of the Zoological Society of Japan)
• EXPLORATION OF TARGET PROTEINS OF ASCIDIAN SPERM PROTEASES(Developmental Biology,Abstracts of papers presented at the 76^ Annual Meeting of the Zoological Society of Japan)
• THE FEATURES OF VAP1-INSDUCED APOPTOSIS IN VASCULAR ENDOTHELIAL CELL(Physiology,Abstracts of papers presented at the 75^ Annual Meeting of the Zoological Society of Japan)
• Co-expression of fibroblastic, histiocytic and smooth muscle cell phenotypes on cultured adherent cells derived from human palatine tonsils : a morphological and immunocytochemical study
• CANDIDATE UBIQUITIN LIGASES, WHICH ARE EXPRESSED IN TESTIS IN THE ASCIDIAN CIONA INTESTINALIS(Developmental Biology,Abstracts of papers presented at the 76^ Annual Meeting of the Zoological Society of Japan)
• Cell type and function of neurons in the ascidian nervous system
• Developmental changes in soluble proteins during the early development of Dictyostelium discoideum
• Antisense RNA Inhibition of the β Subunit of the Dictyostelium discoideum Mitochondrial Processing Peptidase Induces the Expression of Mitochondrial Proteins
• Effects of Proteasome Inhibitors on Fertilization of the Sea Urchin Anthocidaris crassispina(Biochemistry)
• STUDIES ON SELF-INCOMPATIBILITY DURING FERTILIZATION OF THE ASCIDIAN CIONA INTESTINALIS(Developmental Biology,Abstracts of papers presented at the 76^ Annual Meeting of the Zoological Society of Japan)
• 海産無脊椎動物の代表であるカタユウレイボヤCiona intestinalisとニッポンウミシダOxycomanthus japonicus
• 2SC-02 細胞分裂と形態形成の協調 : 神経管閉鎖過程における伸長化したG2期の役割(2SC 一個体イメージング,日本生物物理学会第49回年会(2011年度))
• 2SC-03 光変換型蛍光タンパク質Kaedeを用いたホヤの変態過程における中枢神経系の追跡(2SC 一個体イメージング,日本生物物理学会第49回年会(2011年度))
• Cell lineage and cis-regulation for a unique GABAergic/glycinergic neuron type in the larval nerve cord of the ascidian Ciona intestinalis
• Efficient targeted mutagenesis of the chordate Ciona intestinalis genome with zinc-finger nucleases
• Targeted disruption of exogenous EGFP gene in medaka using zinc-finger nucleases
• Ascidians as excellent chordate models for studying the development of the nervous system during embryogenesis and metamorphosis

もっと見る 閉じる

スポンサーリンク