眼瞼原発の眼窩印環細胞癌例

概要

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Primary signet ring cell carcinoma of the eyelids is a rare tumor. We report herein on the case of a 74-year-old man who noticed swelling of the left eyelid four months previously. The histopathological diagnosis was signet ring cell carcinoma based on a biopsy of the eyelid. Enhanced MRI showed that the tumor had infiltrated the orbit. A systemic examination did not find out any other primary tumor and there was no metastasis. We performed orbital exenteration and postoperative radiotherapy. Six months later, PET-CT detected the recurrence of the carcinoma and lymph node metastasis. In general, primary signet ring cell carcinoma of the eyelids is a diagnosis of exclusion. Periorbital metastases from primary infiltrating carcinomas elsewhere are well known, especially breast carcinoma and gastrointestinal carcinoma. Therefore, a systematic examination is very important to detect the primary carcinoma. To establish the therapy for primary signet ring cell carcinoma, accumulation of cases is required.
耳鼻咽喉科臨床学会の論文
2012-11-01