Genetic polymorphisms in CTLA4 and SLC4A2 are differentially associated with the pathogenesis of primary biliary cirrhosis in Japanese patients
スポンサーリンク
概要
- 論文の詳細を見る
- 2011-10-01
著者
-
Yatsuhashi Hiroshi
長崎大学 医歯薬学総合研究科内科学第一
-
Yatsuhashi Hiroshi
国立病院機構長崎医療センター 呼吸器科
-
Yatsuhashi Hiroshi
Clinical Research Center National Nagasaki Medical Center
-
Ida H
First Department Of Internal Medicine Nagasaki University Hospital Of Medicine And Dentistry Graduat
-
NAKANUMA Yasuni
Department of Human Pathology, Kanazawa University Graduate School of Medicine
-
Nakamuta Makoto
九州大学 医学系学府病態制御内科学
-
Nakamuta M
The Department Of Medicine And Bioregulatory Science Graduate School Of Medical Sciences Kyushu Univ
-
Nakamuta Makoto
九州大学 医学研究院病態制御内科学分野
-
Makita Naomasa
Department Of Gastroenterology National Hospital Organization Kyushu Medical Center
-
Umemura Takeji
信州大学 医学部内科学
-
Komatsu Michiharu
信州大学 医学部内科学
-
Komatsu Michiharu
Division Of Gastroenterology Department Of Internal Medicine Shinshu University School Of Medicine
-
Maki Noboru
Advanced Life Science Institute Inc.
-
Tanaka Eiji
Shinshu Univ. School Of Medicine Matsumoto Jpn
-
Migita Kiyoshi
Clinical Research Center National Hospital Organization (nho) Nagasaki Medical Center
-
Migita Kiyoshi
国立病院機構長崎医療センター
-
Nakashima M
鳥取大学 医学系研究科遺伝子医療学
-
OTA Masao
Department of Legal Medicine, Shinshu University School of Medicine
-
Takeda Naokazu
Department Of Gastroenterology Shinshu University School Of Medicine
-
Horie Hitomi
Institute Of Tropical Medicine (nekken) Nagasaki University
-
Aiba Yoshihiro
Clinical Research Center National Hospital Organization (nho) Nagasaki Medical Center
-
Kondo Hisayoshi
Atomic Bomb Disease Institute Nagasaki University Graduate School Of Biomedical Sciences
-
ISHIBASHI Hiromi
National Hospital Organization (NHO) Nagasaki Medical Center
-
Ishibashi H
National Nagasaki Medical Center Nagasaki Jpn
-
Nakamuta Makoto
Department Of Gastroenterology National Hospital Organization Kyushu Medical Center
-
KIMURA TATSUJI
Advanced Life Science Institute Inc.
-
Komori Atsumasa
Clinical Research Center National Hospital Organization (nho) Nagasaki Medical Center
-
Yasunami Michio
Institute Of Tropical Medicine (nekken) Nagasaki University
-
Nakanishi Yoshitsugu
北海道大学 医学研究科消化器内科
-
Nagao Yasuyuki
Third Department Of Internal Medicine Kyoto Prefectural University Of Medicine
-
Umemura Takeji
Department Of Gastroenterology Shinshu University School Of Medicine
-
Yatsuhashi Hiroshi
Clinical Research Center National Hospital Organization (nho) Nagasaki Medical Center
-
Nakatsuji Yoshiyuki
Department Of Pediatrics Shinshu University School Of Medicine
-
Yoshizawa Kaname
Department Of Gastroenterology Shinshu University School Of Medicine
-
Ikeda Tetsuo
Department Of Surgery Oita Prefectural Hospital
-
Umemura Takeji
信州大学 医学部病態解析診断
-
Ishibashi H
First Department Of Internal Medicine Kyushu University Faculty Of Medicine
-
Joshita Satoru
Department Of Gastroenterology Shinshu University School Of Medicine
-
Tsukamoto Kazuhiro
Department Of Applied Biochemistry Tokai University School Of Engineering
-
Fukushima Nobuyoshi
The First Department Of Internal Medicine Faculty Of Medicine Kyushu University
-
Nakamura Minoru
Clinical Research Center National Hospital Organization (nho) Nagasaki Medical Center
-
Nakamura Minoru
The First Department Of Internal Medicine Faculty Of Medicine Kyusyu University
-
Shimada Masaaki
Clinical Research Center Nho Nagasaki Medical Center
-
WATANABE Yukio
Clinical Research Center, NHO Nagasaki Medical Center
-
Muro Toyokichi
Clinical Research Center Nho Nagasaki Medical Center
-
NAKAMUTA Makoto
Headquarters of PBC Research in the National Hospital Organization Study Group for Liver Disease in
-
HAYASHI Shigeki
Headquarters of PBC Research in the National Hospital Organization Study Group for Liver Disease in
-
SAOSHIRO Takeo
Headquarters of PBC Research in the National Hospital Organization Study Group for Liver Disease in
-
Inamine Tatsuo
Department Of Pharmacotherapeutics Nagasaki University Graduate School Of Biomedical Sciences
-
Nakanishi Yoshitsugu
Department Of Surgical Oncology Division Of Cancer Medicine Hokkaido University Graduate School Of M
-
UMEMURA Takeji
Division of Hepatology and Gastroenterology, Department of Medicine
-
Watanabe Yukio
Clinical Research Center Nho Nagasaki Medical Center
-
Hayashi Shigeki
Headquarters Of Pbc Research In The National Hospital Organization Study Group For Liver Disease In
-
Saoshiro Takeo
Headquarters Of Pbc Research In The National Hospital Organization Study Group For Liver Disease In
-
Joshita Satoru
Division Of Hepatology And Gastroenterology Department Of Medicine
-
Tsukamoto Kazuhiro
Department Of Pharmacotherapeutics Nagasaki University Graduate School Of Biomedical Sciences
-
Yoshizawa Kaname
Division Of Hepatology And Gastroenterology Department Of Medicine
-
Nakayama Yoshiko
Department Of Human Pathology Kanazawa University Graduate School Of Medicine
-
Tanaka Eiji
Division Of Cardiology Komatsushima Red Cross Hospital
-
Tanaka E
Department Of Medicine Shinshu University School Of Medicine
-
Sugi Kazuhiro
Headquarters Of Pbc Study Group In National Hospital Organization Study Group For Liver Disease In Japan (nhoslj)
-
HORIE Hitomi
Clinical Research Center, National Hospital Organization Nagasaki Medical Center
-
FUKUSHIMA Nobuyoshi
Headquarters of PBC Study Group in National Hospital Organization Study Group for Liver Disease in Japan (NHOSLJ)
-
KOUNO Hiroshi
Headquarters of PBC Study Group in National Hospital Organization Study Group for Liver Disease in Japan (NHOSLJ)
-
OTA Hajime
Headquarters of PBC Study Group in National Hospital Organization Study Group for Liver Disease in Japan (NHOSLJ)
-
MURO Toyokichi
Headquarters of PBC Study Group in National Hospital Organization Study Group for Liver Disease in Japan (NHOSLJ)
-
WATANABE Yukio
Headquarters of PBC Study Group in National Hospital Organization Study Group for Liver Disease in Japan (NHOSLJ)
-
NAKAMURA Yoko
Headquarters of PBC Study Group in National Hospital Organization Study Group for Liver Disease in Japan (NHOSLJ)
-
KOMEDA Toshiki
Headquarters of PBC Study Group in National Hospital Organization Study Group for Liver Disease in Japan (NHOSLJ)
-
SHIMADA Masaaki
Headquarters of PBC Study Group in National Hospital Organization Study Group for Liver Disease in Japan (NHOSLJ)
-
MASAKI Naohiko
Headquarters of PBC Study Group in National Hospital Organization Study Group for Liver Disease in Japan (NHOSLJ)
-
KOMATSU Tatsuji
Headquarters of PBC Study Group in National Hospital Organization Study Group for Liver Disease in Japan (NHOSLJ)
-
YAGURA Michiyasu
Headquarters of PBC Study Group in National Hospital Organization Study Group for Liver Disease in Japan (NHOSLJ)
-
KOGA Michiaki
Headquarters of PBC Study Group in National Hospital Organization Study Group for Liver Disease in Japan (NHOSLJ)
-
ISHIBASHI Hiromi
Department of Hepatology, Nagasaki University Graduate School of Biomedical Sciences
-
Horie Hitomi
Clinical Research Center National Hospital Organization Nagasaki Medical Center
-
Nakayama Yoshiko
Department Of Pediatrics Shinshu University School Of Medicine
-
Ishibashi Hiromi
Department Of Hepatology Nagasaki University Graduate School Of Biomedical Sciences
-
Joshita Satoru
Department of Legal Medicine, Shinshu University School of Medicine
関連論文
- Semi-quantitative discrimination of HBV mutants using allele-specific oligonucleotide hybridization with Handy Bio-Strand(METHODS)
- Tumor necrosis factor-α induces the aberrant expression of mucus core protein-2 in non-neoplastic biliary epithelial cells via the upregulation of CDX2 in chronic cholangitis
- Heterogeneity of Clinical Manifestation of Hypertrophic Cardiomyopathy Caused by Deletion of Lysine 183 in Cardiac Troponin I Gene : Insight From Two Autopsy Cases With an Identical Sarcomeric Gene Mutation
- Analysis of HLA-DRB1 polymorphisms in Japanese patients with primary biliary cirrhosis (PBC) : The HLA-DRB1 polymorphism determines the relative risk of antinuclear antibodies for disease progression in PBC
- Proposal of histological criteria for intraepithelial atypical/proliferative biliary epithelial lesions of the bile duct in hepatolithiasis with respect to cholangiocarcinoma : Preliminary report based on interobserver agreement
- Pathology of peripheral intrahepatic cholangiocarcinoma with reference to tumorigenesis
- Clinicopathological significance of antinuclear antibodies in non-alcoholic steatohepatitis
- Involvement of Escherichia coli in pathogenesis of xanthogranulomatous cholecystitis with scavenger receptor class A and CXCL16-CXCR6 interaction
- Liver steatosis, but not fibrosis, is associated with insulin resistance in nonalcoholic fatty liver disease
- Local balance of transforming growth factor-β1 secreted from cholangiocarcinoma cells and stromal-derived factor-1 secreted from stromal fibroblasts is a factor involved in invasion of cholangiocarcinoma
- Characterization of biliary intra-epithelial lymphocytes at different anatomical levels of intrahepatic bile ducts under normal and pathological conditions : Numbers of CD4^+CD28^- intra-epithelial lymphocytes are increased in primary biliary cirrhosis
- Diagnosing clinical subsets of autoimmune liver diseases based on a multivariable model
- Are bile duct lesions of primary biliary cirrhosis distinguishable from those of autoimmune hepatitis and chronic viral hepatitis? Interobserver histological agreement on trimmed bile ducts
- Expression profiles of MUC mucin core protein in the intrahepatic biliary system: Physiological distribution and pathological significance
- S1-4 Expression profiles of MUC mucin core protein in intrahepatic biliary system(THE 45TH ANNUAL MEETING OF THE JAPAN SOCIETY OF HISTOCHEMISTRY AND CYTOCHEMISTRY)
- Expression of MAGE-A3 in intrahepatic cholangiocarcinoma and its precursor lesions
- Anatomic and molecular pathology of intrahepatic cholangiocarcinoma
- Apoptosis of murine cultured biliary epithelial cells induced by glycochenodeoxycholic acid involves Fas receptor and its ligand
- Combined hepatocellular and cholangiocarcinoma with marked squamous cell carcinoma components arising in non-cirrhotic liver
- Osteopontin is involved in the formation of epithelioid granuloma and bile duct injury in primary biliary cirrhosis
- Perihilar cholangiocarcinoma arising in hepatitis C virus-related liver cirrhosis with hepatocellular carcinoma
- Minute scirrhous hepatocellular carcinomas undergoing different carcinogenetic processes
- Intraductal papillary neoplasm of the bile duct extending superficially from the intrahepatic to extrahepatic bile duct
- Transformation of p53-positive papillary thyroid carcinoma to anaplastic carcinoma of the liver following postoperative radioactive iodine-131 therapy
- Prediction of DAS28-ESR remission at 6 months by baseline variables in patients with rheumatoid arthritis treated with etanercept in Japanese population
- Autoimmune hepatitis in a patient with systemic lupus erythematosus : a case report
- Analysis of 388 cases of primary sclerosing cholangitis in Japan Presence of a subgroup without pancreatic involvement in older patients
- A significantly impaired natural killer cell activity due to a low activity on a per-cell basis in rheumatoid arthritis
- Twenty-four-week follow-up examination of a leukocytapheresis therapy in rheumatoid arthritis
- Characterization of anticytoplasmic antibodies in patients with systemic autoimmune diseases
- A case of amyloidosis secondary to rheumatoid arthritis complicated with Graves' ophthalmopathy
- Atypical mycobacteriosis in two patients with rheumatoid arthritis
- Human intrahepatic biliary epithelial cell as possible modulator of hepatic regeneration : Potential role of biliary epithelial cell for hepatic remodeling in vivo
- Endoscopic retrograde cholangiography versus peroral cholangioscopy to evaluate intraepithelial tumor spread in biliary cancer
- Primary acinar cell carcinoma of the ampulla of Vater
- Biotin-related proteins of 70 and 72 kDa in gallbladder bile in primary biliary cirrhosis
- Lipomatous pseudohypertrophy of the pancreas in a patient with cirrhosis due to chronic hepatitis B
- Dendritic cells in portal tracts in chronic hepatitis C and primary biliary cirrhosis with relevance to bile duct damage: an immunohistochemical study^1
- -0905-THREE-DEMENSIONAL RECONSTRUCTION OF RESECTED SPECIMENS FROM PATIENTS TITH VENTRICULAR TACHYCARDIA : THE 54th ANNUAL SCIENTIFIC MEETING OF THE JAPANESE CIRCULATION SOCIETY
- Molecular mechanisms of cholangiopathy in primary biliary cirrhosis
- A modified Japan Integrated Stage score for prognostic assessment in patients with hepatocellular carcinoma
- Pathology and immunopathology of immunoglobulin G4-related sclerosing cholangitis : The latest addition to the sclerosing cholangitis family
- Expression of sialyl-Tn, Tn and T antigens in primary liver cancer
- Expression of MUC2, MUC5AC and MUC6 apomucins in carcinoma, dysplasia and non-dysplastic epithelia of the gallbladder
- Increasing hepatitis C virus-associated hepatocellular carcinoma mortality and aging : Long term trends in Japan
- Nonalcoholic Steatohepatitis with Improved Hepatic Fibrosis after Weight Reduction
- Amyloid a Protein Amyloidosis in a Patient with Plasma Cell Dyscrasia
- Geranylgeraniol, an Intermediate Product in Mevalonate Pathway, Induces Apoptotic Cell Death in Human Hepatoma Cells : Death Receptor-independent Activation of Caspase-8 with Down-regulation of Bcl-xL Expression
- Attenuation of Responsiveness to Interferon-α Treatment by Preceded Overactivation of Interferon-mediated Pathway in Patients Chronically Infected by Hepatitis C Virus
- Two cases of hepatopulmonary syndrome with improved liver function following long-term oxygen therapy
- Biliary innate immunity and cholangiopathy
- A case of cold agglutinin disease in the course of treatment for polymyalgia rheumatica
- Predictive role of anti-gp210 and anticentromere antibodies in long-term outcome of primary biliary cirrhosis
- Histone deacetylase inhibitor (SAHA) and repression of EZH2 synergistically inhibit proliferation of gallbladder carcinoma
- Retroperitoneal mucinous cystadenoma : Report of two cases and review of the literature
- Successful plasmapheresis in alveolar hemorrhage associated with systemic lupus erythematosus
- Elevated serum soluble CD8 level in autoimmune hepatitis and the effect of corticosteroid therapy
- Propylthiouracil-Induced severe hepatitis: A case report and review of the literature
- Establishment and structural analysis of human mAb to E2 component of the 2-oxoglutarate dehydrogenase complex generated from a patient with primary biliary cirrhosis
- Tyrphostin AG 1478 Accelerates Hydrogen Peroxide-Induced Apoptosis in A431 Cells
- Ciliated hepatic cyst without smooth muscle layer : A variant of ciliated hepatic foregut cyst?
- Recurrence of mucosal carcinoma of the bile duct, with superficial flat spread, 12 years after operation
- Autoimmune hepatitis associated with bile duct injury resembling chronic non-suppurative destructive cholangitis
- A case of periodic-fever-syndrome-like disorder with lipodystrophy, myositis, and autoimmune abnormalities
- 2-1). Antigen Peptide Analog : Induction of T cell Anergy in Primary Biliary Cirrhosis
- Type1 and type2 memory T cells imbalance shown by expression of intrahepatic chemokine receptors relates to pathogenesis of primary biliary cirrhosis
- Spontaneous occurrence of chronic non-suppurative destructive cholangitis and antimitochondrial autoantibodies in MRL/lpr mice : Possible animal model for primary biliary cirrhosis
- Spindle Cell-Type Undifferentiated Carcinoma of the Common Bile Duct of the Hepatic Hilus
- Association analysis of cytotoxic T-lymphocyte antigen 4 gene polymorphisms with primary biliary cirrhosis in Japanese patients
- Fibulin-5 is involved in phlebosclerosis of major portal vein branches associated with elastic fiber deposition in idiopathic portal hypertension
- Retreatment with interferon-α at dosages or period increased by 1.3 times is effective for treatment for transient responders and non-responders in chronic hepatitis C patients
- Aneurysmal Intraheptic Portosystemic Venous Shunt Associated with Idiopathic Portal Hypertension : A Lesion Evaluated by a 3 D Image Reconstructed from Power Doppler Flow Imaging
- Are esophagogastric varices a late manifestation in primary biliary cirrhosis?
- Diffuse biliary tract involvement mimicking primary sclerosing cholangitis in an experimental model of chronic graft-versus-host disease in mice
- Primary cholangiohepatitis as an alternative name for primary biliary cirrhosis
- Hepatocellular carcinoma in primary biliary cirrhosis at an early histologic stage: Coincidental or causally related?
- An immunohistochemical study on a case of granulocyte-colony stimulating factor-producing gall-bladder carcinoma
- Peribiliary cysts have at least two different pathogeneses
- Steatosis and hepatic expression of genes regulating lipid metabolism in Japanese patients infected with hepatitis C virus
- Cutaneous vasculitis induced by TNF inhibitors : a report of three cases
- Switching to the anti-interleukin-6 receptor antibody tocilizumab in rheumatoid arthritis patients refractory to antitumor necrosis factor biologics
- Prediction of DAS28-CRP remission in patients with rheumatoid arthritis treated with tacrolimus at 6 months by baseline variables
- Nonalcoholic fatty liver disease in Japanese junior high school students : its prevalence and relationship to lifestyle habits
- Intraductal tubular neoplasm of the common bile duct
- Biliary deposition of Liesegang rings presenting as a polypoid mass in the liver : Previously unrecognized lesion
- Bile ductular cell reaction with senescent hepatocytes in chronic viral hepatitis is lost during hepatocarcinogenesis
- Intraductal papillary-mucinous neoplasm of the pancreas associated with polycystic liver and kidney disease
- Pathology and pathogenesis of portal venopathy in idiopathic portal hypertension : Hints from systemic sclerosis
- Submassive hepatocellular necrosis associated with infiltration by peripheral T-cell lymphoma of cytotoxic phenotype : Report of two cases
- Successful treatment of chronic lupus myocarditis with prednisolone and mizoribine
- Long-term efficacy of intravenously administered immunoglobulin in a case of polymyositis with limited application of steroid therapy.
- A polymorphism in the integrin αV subunit gene affects the progression of primary biliary cirrhosis in Japanese patients
- Evaluation of risk factors for the development of cirrhosis in autoimmune hepatitis : Japanese NHO-AIH prospective study
- Alpha-fetoprotein above normal levels as a risk factor for the development of hepatocellular carcinoma in patients infected with hepatitis C virus
- Integrated fibrosis scoring by ultrasonography predicts the occurrence of hepatocellular carcinoma in patients with chronic hepatitis C virus infection
- Contribution of an adenine to guanine single nucleotide polymorphism of the matrix metalloproteinase-13 (MMP-13) -77 promoter region to the production of anticyclic citrullinated peptide antibodies in patients with HLA-DRB1^*shared epitope-negative rheuma
- Reduction in serum levels of substance P in patients with rheumatoid arthritis by etanercept, a tumor necrosis factor inhibitor
- Genetic polymorphisms in CTLA4 and SLC4A2 are differentially associated with the pathogenesis of primary biliary cirrhosis in Japanese patients
- Delayed treatment with tumor necrosis factor inhibitors in incomplete responders to synthetic disease-modifying anti-rheumatic drugs shows and excellent effect in patients with very early rheumatoid arthritis with poor prognosis factors
- Treatment discontinuation in patients with very early rheumatoid arthritis in sustained simplified disease activity index remission after synthetic disease-modifying anti-rheumatic drug administration