Risk of Bronchioloalveolar Carcinoma in Patients with Human T-cell Lymphotropic Virus Type 1 (HTLV-I) : Case-control Study Results
スポンサーリンク
概要
- 論文の詳細を見る
Background: Human T-cell lymphotropic virus type 1 (HTLV-I) causes not only adult T-cell leukemia (ATL) but also HTLV-I associated T-cell bronchioloalveolitis, which is often chronic and subclinical. We have experienced eight HTVL-I carriers with bronchioloalveolar carcinoma, which is known to arise from bronchioloalveolar pneumocytes. This case–control study clarified the risk of bronchioloalveolar carcinoma in HTLV-I carriers.Materials and Methods: During the past four years, 212 lung cancer patients were examined for serum anti-HTLV-I antibody. They underwent surgical treatment for lung cancer at Kumamoto University Hospital. Of these, 8 (4%) were HTLV-I carriers. As controls for this case-control study, we selected 24 HTLV-I negative-lung cancer patients (1:3 case-control ratio) matched for sex, age, and smoking status. The distributions of histological types of lung cancer were compared between the case (HTLV-I positive) and control (HTLV-I negative) groups.Results: Histological types of the 8 HTLV-I carriers were bronchioloalveolar carcinoma in 6 patients and adenocarcinoma with bronchioloalveolar carcinoma component in 2. The prevalence of bronchioloalveolar carcinoma in HTLV-I carriers, 6 of 8 (75%), was significantly higher than the 6 of 24 (25%) in HTLV-I negative patients (p = 0.02). The prevalence of bronchioloalveolar carcinoma or adenocarcinoma with bronchioloalveolar carcinoma component in HTLV-I carriers, 8 of 8 (100%), was also significantly higher than the 13 of 24 (54%) in HTLV-I negative patients (p = 0.02).Conclusion: HTLV-I might be one risk of bronchioloalveolar carcinoma, probably because of inflammatory and/or immunologic responses involving bronchioloalveolar pneumocytes.
- Annals of Thoracic and Cardiovascular Surgery 編集委員会の論文
- 2011-02-01
著者
-
IYAMA Kenichi
Department of Pathology, Kumamoto University Hospital
-
Mori Takeshi
Department Of Applied Chemistry Kyushu University
-
Nomori Hiroaki
Division Of General Thoracic Surgery Department Of Surgery School Of Medicine Keio University
-
Okamoto Tatsuya
Department Of Clinical Biology And Medicine Institute Of Health Biosciences The University Of Tokush
-
Kamakura Mitsuhiro
Department Of Clinic For Infectious Diseases Graduate School Of Health Management Keio University
-
Okamoto Tatsuya
Department Of Microbiology Graduate School Of Medical And Pharmaceutical Sciences Kumamoto Universit
-
Nomori Hiroaki
Division Of General Thoracic Surgery Department Of Surgery Graduate School Of Medicine Keio Universi
-
Mori Takeshi
Department Of Thoracic Surgery Graduate School Of Medical And Pharmaceutical Sciences Kumamoto Unive
-
Mori Takeshi
Department Of Applied Chemistry Graduate School Of Engineering Kyushu University
-
Iyama Kenichi
Department Of Pathology Graduate School Of Medical And Pharmaceutical Sciences Kumamoto University
-
Mori Takeshi
Department of Applied Chemistry and Chemical Engineering
関連論文
- Usefulness of Collagen Gel Droplet Embedded Culture-Drug Sensitivity Test for Gynecological Cancers
- Hairy cell leukemia responsive to anti-thymocyte globulin used as immunosuppressive therapy for aplastic anemia
- Aspergilloma: comparison of treatment methods and prognoses
- General characterization of Antarctic micrometeorites collected by the 39th Japanese Antarctic Research Expedition: Consortium studies of JARE AMMs (III)
- A consortium study of Antarctic micrometeorites recovered from the Dome Fuji Station
- IIB-05 Regulatory mechanism of differential expression of basement membrane type IV collagen α1, α2, α5 and α6 chains in colon cancer and colon cancer cell lines(THE 46TH ANNUAL MEETING OF THE JAPAN SOCIETY OF HISTOCHEMISTRY AND CYTOCHEMISTRY)
- Electro-Sensitive Microcapsule Immobilized Ferroelectric Liquid Crystal
- Reduced Carnitine Level Causes Death from Hypoglycemia : Possible Involvement of Suppression of Hypothalamic Orexin Expression During Weaning Period
- Polydispersity as a Parameter for Indicating the Thermal Stability of Proteins by Dynamic Light Scattering
- 2P-256 二面偏波式干渉技術を用いた熱応答性高分子の分子ダイナミクス解析(計測,第47回日本生物物理学会年会)
- A Peptide Microarray for the Detection of Protein Kinase Activity in Cell Lysate
- Temperature-responsive Poly(dehydroalanine)s : Diversifying Phase Transition Temperatures Utilizing α,α-Disubstituted Motif
- 2P589 Structure and functional regulation of DNA complex formed with Cell-Signal responsive Gene Carrier(55. Drug design and delivery,Poster Session,Abstract,Meeting Program of EABS &BSJ 2006)
- Histological liver injury and surgical outcome after FOLFOX followed by a hepatectomy for colorectal liver metastases in Japanese patients
- Delays and Continuation of Hospital Visits Among HIV-Infected Persons and AIDS Cases in Japan
- A Novel Mechanism of Fluconazole Resistance Associated with Fluconazole Sequestration in Candida albicans Isolates from a Myelofibrosis Patient
- Serolodiagnosis of Some Types of Aspergillosis using Culture Filtrate Antigens from Aspergillus fumigatus
- Enhanced Vascular Permeability in Solid Tumor Involving Peroxynitrite and Matrix Metalloproteinases
- Development of Gold Nanorods That Accumulatate into Tumor
- Small Solid Pseudopapillary Tumor of the Pancreas in a 32-Year-Old Man : Report of a Case
- Primary coexistent neuroendocrine carcinoma, hepatoid adenocarcinoma, and tubular adenocarcinoma of the stomach with focal trophoblastic differentiation in metastatic lymph nodes
- A Case of Sclerosing Hemangioma Evaluated with Diffusion-Weighted Magnetic Resonance Imaging and ^F-Fluorodeoxyglucose Positron Emission Tomography
- A Case of Primary Mediastinal Ependymoma
- Positron emission tomography in lung cancer
- A Segmentectomy of the Right Upper Lobe Has an Advantage over a Right Upper Lobectomy Regarding the Preservation of the Functional Volume of the Right Middle Lobe : Analysis by Perfusion Single-Photon Emission Computed Tomography/Computed Tomography
- Kissing Pleural Metastases from Metastatic Osteosarcoma of the Lung
- A STUDY OF THE CHARACTERISTICS OF TRACE ELEMENTS IN THE HAIR OF JAPANESE; INTERRELATIONSHIPS AND RATIOS OF TRACE ELEMENTS IN HAIR
- Formation of DNA-Carrying Colloidal Particle from Poly(N-isopropylacrylamide)-graft-DNA Copolymer and Its Assembly through Hybridization
- Sparganum mansoni parasitic infection in the lung showing a nodule
- The Efficacy of Epidural Analgesia after Video-Assisted Thoracoscopic Surgery : A Randomized Control Study
- Optimization of Peptide Density on Microarray Surface for Quantitative Phosphoproteomics
- Extrapleural Pneumonectomy via a Lower Door Open Thoracotomy with Reconstruction of the Diaphragm and Pericardium Using Autologous Materials for Mesothelioma
- Nitric oxide produced in Peyer's patches exhibits antiapoptotic activity contributing to an antimicrobial effect in murine salmonellosis
- Parallel β-sheet as a Novel Template for Polymerization of Diacetylene
- Prediction and management of a low-lying costal arch which restricts the operative working space during laparoscopic cholecystectomy
- Sentinel Nodes in Lung Cancer : Review of Our 10-Year Experience
- Nanomolar Quantification and Identification of Various Nitrosothiols by High Performance Liquid Chromatography Coupled with Flow Reactors of Metals and Griess Reagent
- Completely isolated alimentary tract duplication in a neonate
- Detection of Aflatoxins in Autopsied Materials from a Patient Infected with Aspergillus flavus
- Fight Against Infectious Diseases
- How Many Pathological T1N0M0 Non-Small Cell Lung Cancers Can Be Completely Resected in One Segment? Special Reference to High-Resolution Computed Tomography Findings
- Receiver-Operating Characteristic Analysis of Leukocyte Counts and Serum C-Reactive Protein Levels in Children with Advanced Appendicitis
- A novel tumor-associated antigen, cell division cycle 45-like can induce cytotoxic T-lymphocytes reactive to tumor cells
- Peptides derived from human insulin-like growth factor-II mRNA binding protein 3 can induce human leukocyte antigen-A2-restricted cytotoxic T lymphocytes reactive to cancer cells
- Stability Change of DNA-Carrying Colloidal Particle Induced by Hybridization with Target DNA
- Risk of Bronchioloalveolar Carcinoma in Patients with Human T-cell Lymphotropic Virus Type 1 (HTLV-I) : Case-control Study Results
- Repeat FDG-PET for Predicting Pathological Tumor Response and Prognosis after Neoadjuvant Treatment in Nonsmall Cell Lung Cancer : Comparison with Computed Tomography
- Diaphragm Perforation after Radio-Frequency Ablation for Metastatic Lung Cancer
- Three Young Osteosarcoma Patients with Small Adenocarcinoma or Atypical Adenomatous Hyperplasia of the Lung
- Pulmonary pleomorphic carcinoma producing granulocyte-macrophage colony-stimulating factor : report of a case
- Innovative segmentectomy to remove the posterior segment of the lower lobe (S^) of the lung
- Combined subsegmentectomy for S^2_b (horizontal subsegment of the posterior segment) and S^3_a (lateral subsegment of the anterior segment) in the right upper pulmonary lobe
- Epigallocatechin gallate inhibits sphere formation of neuroblastoma BE(2)-C cells
- Complete Laceration of the Middle Lobe Bronchus Caused by Blunt Trauma
- Sequential Release of Single-stranded DNAs from Gold Nanorods Triggered by Near-infrared Light Irradiation
- Utility of Multiplex PCR in Detecting the Causative Pathogens for Pediatric Febrile Neutropenia
- cT1aN0M0 lung adenocardnoma treated with left S9+10 segmentectomy followed by completion lobectomy for a solitary metastasis (isolated tumor cells) in the neighboring segmental lymph node
- Place of Death of Pediatric Cancer Patients in a Single Institute during 7 Years
- Partial Anomalous Pulmonary Venous Connection Associated with Lung Cancer in the Same Lobe: Report of a Case
- A Case of Desmoid-Type Fibromatosis Arising after Thoracotomy for Lung Cancer with a Review of the English and Japanese Literature
- Anterior Mediastinal Lymphoma Arising after Resection of an Invasive Thymoma and Immunosuppressive Therapy for Complicated Myasthenia Gravis
- Expression of the Nucleocapsid Protein Gene of the Canine Distemper Virus.
- Hydrogen atom transfer in the quenching of pyrene fluorescence by amines.
- Hepatoblastoma Metastasis Confined to the Pulmonary Artery: Report of a Case
- A Liposome Reversibly Coated with Serum Albumin