Left Ventricular Basal Myocardial Scarring Detected by Delayed Enhancement Magnetic Resonance Imaging Predicts Outcomes After Surgical Therapies for Patients With Ischemic Mitral Regurgitation and Left Ventricular Dysfunction
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概要
- 論文の詳細を見る
Background: Treatment of heart failure by surgical procedures such as mitral annuloplasty and left ventricular (LV) restoration is increasingly applied to patients with ischemic mitral regurgitation (IMR) and LV dysfunction. The clinical efficacy of delayed enhancement magnetic resonance imaging (DE-MRI) was studied to predict LV functional recovery and adverse outcomes after these therapies. Methods and Results: In 26 patients with IMR and a LV ejection fraction <40%, DE-MRI was performed before the operation and the percentage of regional myocardial scarring was quantified at the basal, mid, and apical LV. Calculated percentage of fibrosis was 12±12% at the base, 24±15% at the mid, and 35±31% at the apical LV. The degree of basal fibrosis was a significant predictor of less improvement of LV ejection fraction and postoperative restrictive diastolic filling. A linear correlation was noted between basal fibrosis and postoperative ejection fraction (P=0.001, R=-0.61), the early to late mitral valve flow ratio (P=0.0005, R=0.66), and deceleration time (P=0.01, R=-0.51). Logistic regression analysis demonstrated that the percentage of basal fibrosis was the independent predictor of postoperative adverse clinical outcomes (odds ratio, 1.26; P=0.04). Conclusions: In patients undergoing surgical heart failure therapy for IMR, the extent of basal fibrosis characterized by DE-MRI might be a useful predictor of postoperative LV systolic and diastolic functional recovery and postoperative adverse outcomes. (Circ J 2011; 75: 148-156)
- 社団法人 日本循環器学会の論文
- 2010-12-25
著者
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Sawa Yoshiki
Department Of Cardiovascular Surgery Osaka Graduate School Of Medicine
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Yamaguchi Takahiro
Division Of Cardiovascular Surgery Osaka University Graduate School Of Medicine:department Of Surger
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Sakata Y
Center For Advanced Medical Engineering And Informatics Osaka University
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HAMADA SEIKI
Department of Radiology, Osaka University Graduate School of Medicine
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Sasako Yoshikado
Department Of Cardiovascular Surgery Osaka University
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Sakata Y
Cardiovascular Center Chiba-hokusoh Hospital Nippon Medical School
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Sasako Yoshikado
Department Of Cardiovascular Surgery Osaka University Graduate School Of Medicine
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Matsumiya Goro
Division Of Cardiovascular Surgery Department Of Surgery Osaka University Graduate School Of Medicin
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Sakata Yasushi
大阪大学 医学系研究科循環器内科学
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Sakata Yasushi
Department Of Internal Medicine And Therapeutics Osaka University Graduate School Of Medicine
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Sakata Yasuhiko
Department Of Cardiovascular Medicine Osaka University Graduate School Of Medicine
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SAKAGUCHI Taichi
Division of Cardiovascular Surgery, Department of Surgery, Osaka University Graduate School of Medic
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YAMAUCHI Takashi
Division of Cardiovascular Surgery, Department of Surgery, Osaka University Graduate School of Medic
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Miyagawa Shigeru
Division Of Cardiovascular Surgery Department Of Surgery Osaka University Graduate School Of Medicin
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Miyagawa Shuji
大阪大学 医学系研究科外科学講座心臓血管外科学
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Syudo Yasuhiro
大阪大学 心臓血管外科
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Sakaguchi Taichi
Division Of Cardiovascular Surgery Department Of Surgery Osaka University Graduate School Of Medicin
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Sato Yuichi
Department Of Imaging Health Park Clinic Kurosawa
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Sawa Yoshiki
Division Of Cardiovascular Surgery Department Of Surgery Osaka University Graduate School Of Medicin
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Takeda Koji
Division of Cardiothoracic Surgery, Department of Surgery, Osaka University Graduate School of Medic
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Suzuki Y
Department Of Cardiovascular Medicine Osaka University Graduate School Of Medicine
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Shirakawa Yukitoshi
First Department Of Surgery Osaka University Medical School
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Matsumiya Goro
Division Of Cardiovascular Surgery Department Of Surgery E1 Osaka University Graduate School Of Medi
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Takeda Koji
Department Of Cardiovascular Surgery Osaka University Graduate School Of Medicine
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Suematsu Yoshihiro
Department of Cardiothoracic Surgery
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Matsumiya Gorou
Department Of Cardiovascular Surgery Osaka University Graduate School Of Medicine
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Seino Yoshihiko
First Department Of Internal Medicine Nippon Medical School
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Toda Koichi
Department Of Cardiovascular Surgery Labor Health And Welfare Organization Osaka Rosai Hospital
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Suzuki Y
Protect (prospective Trial Of Cardioprotective Effect Of Carperitide Treatment) Study Group
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Yokoyama Shin-ichiro
Second Department Of Internal Medicine Nihon University School Of Medicine
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Yoda Shunichi
Division Of Cardiology Nihon University School Of Medicine
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Suzuki Yasushi
Department Of Cardiovascular Medicine Osaka University Graduate School Of Medicine
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Hamada Seiki
Department Of Radiology National Cardiovascular Center
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Toda Koichi
Japan Labour Health And Welfare Organization Osaka Rosai Hospital
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Yokoyama Shinichiro
Division Of Cardiology Department Of Medicine Nihon University School Of Medicine
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Hamada Seiki
Department Of Radiology Osaka University Graduate School Of Medicine
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Shimazaki Yasuhisa
Department Of Radiology Ikeda City Hospital
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Sawa Yoshiki
Division Of Cardiology Department Of Medicine Nihon University School Of Medicine
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Takeda Koji
Department Of Cardiovascular Surgery Sakurabashi Watanabe Hospital
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Matsumiya Goro
Division Of Cardiovascular Surgery Department Of Surgery Osaka University Graduate School Of Medicin
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Sawa Yoshiki
Division Of Cardiovascular Surgery Department Of Surgery Osaka University Graduate School Of Medicin
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Matsumiya Goro
Division Of Cardiovascular Surgery Department Of Surgery Osaka University Graduate School Of Medicin
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Selno Yoshihiko
Division Of Ccu And Icu Nippon Medical School
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Sawa Yoshiki
Department Of Cardiovascular Surgery
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Sawa Yoshiki
Division Of Cardiovascular Surgery Department Of Surgery Osaka University Graduate School Of Medicin
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Shirakawa Yukitoshi
Department Of Cardiovascular Surgery Osaka University Graduate School Of Medicine
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Shimazaki Yasuhisa
The First Department Of Surgery Osaka University Medical School
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Kawamura Masashi
Department Of Cardiovascular Surgery Graduate School Of Medicine Osaka University
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Yamauchi Takashi
Department Of Cardiovascular Surgery Sakurabashi Watanabe Hospital
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