Hypocholesterolemic Effect of Lactococcus lactis subsp. lactis biovar diacetylactis N7 and Lactococcus lactis subsp. lactis 527 Strains in SD Rats
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概要
- 論文の詳細を見る
The effect of Lactococcus lactis subsp. lactis biovar diacetylactis N7 (LACC-N7) and Lactococcus lactis subsp. lactis 527 (LACC-527) strains isolated from dairy products on serum cholesterol levels in the SD rats were investigated. The administration of LACC-N7 significantly decreased total serum cholesterol (p<0.001) and triglycerides (p<0.05) and increased HDL-cholesterol ratio to total cholesterol (p<0.05) at 6 weeks post-administration. LACC-527 had an effect on total serum cholesterol (p<0.05) and HDL-cholesterol ratio to total cholesterol (p<0.05) at 6 weeks and triglycerides (p<0.01) at 4 weeks post-administration. Enterococcus faecium (ENT-1) also significantly decreased total serum cholesterol (p<0.001), and increased the HDL-cholesterol ratio to total cholesterol (p<0.05). These results suggest that LACC-N7 and LACC-527 would be effective as probiotics for the prevention of hypercholesterolemia and fatty liver.
- 日本ビフィズス菌センターの論文
- 2005-01-01
著者
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KIM So-Young
Department of Dermatology, Seoul National University College of Medicine
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Kim So-young
Department Of Biochemistry And Molecular Biology Laboratory Of Cellular Signaling Cancer Research In
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Ohmomo Sadahiro
Japan International Research Center For Agricultural Sciences
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Kim So-young
Department Of Food Science And Technology And Research Center For Bioresource And Health Chungbuk Na
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Kimoto Hiromi
National Institute Of Animal Industry
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Kimoto Hiromi
National Institute Of Livestock And Grassland Science
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LEE Wan-Kyu
College of Veterinary Medicine and Research Institute of Veterinary Medicine, Chungbuk National Univ
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LIM Hyeong-Jun
College of Veterinary Medicine and Research Institute of Veterinary Medicine, Chungbuk National Univ
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TASHIRO Yasuhito
Meiji Seika Kaisha, Ltd.
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TAKEBE Hideki
Meiji Seika Kaisha, Ltd.
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Lee Wan-kyu
College Of Veterinary Medicine And Research Institute Of Veterinary Medicine Chungbuk National Unive
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Lim Hyeong-jun
College Of Veterinary Medicine And Research Institute Of Veterinary Medicine Chungbuk National Unive
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Tashiro Yasuhito
Meiji Seika Kaisha Ltd.
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Takebe Hideki
Meiji Seika Kaisha Ltd.
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Kim So-young
Department Of Biochemistry And Molecular Biology Cancer Research Center Seoul National University Co
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