Hypersensitivity to Hydroxyl Radicals in Rat Basilar Artery After Subarachnoid Hemorrhage
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概要
- 論文の詳細を見る
Vasospasm after subarachnoid hemorrhage is a serious complication and we have been investigating the relationship between vasoconstrictors and vasospasm after subarachnoid hemorrhage. The present study was designed to investigate the vasocontractile responses to reactive oxygen species in isolated rat basilar arteries from the control and experimental subarachnoid hemorrhage rats. Contractile responses to hydroxyl radicals in basilar arteries from subarachnoid hemorrhage rats were 3 – 6-fold higher than those in control rats. The present results clearly indicate that hypersensitivity to hydroxyl radicals may contribute to the vasospasm after subarachnoid hemorrhage.
- 社団法人 日本薬理学会の論文
- 2006-03-20
著者
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SHIMIZU Yoshiharu
Department of Community Health, School of Medicine, Tokai University
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Shimizu Yoshiharu
Department Of Community Health School Of Medicine Tokai University
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Ji Xu
Pharmacology Division Ri Center Kyoto University
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KURAHASHI Kazuyoshi
Pharmacology Division, Radioisotope Research Center, Kyoto University
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NISHIHASHI Tsuyoshi
Pharmacology Division, RI Center, Kyoto University
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TRANDAFIR Cristina
Pharmacology Division, RI Center, Kyoto University
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WANG Aimin
Pharmacology Division, RI Center, Kyoto University
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Wang Aimin
Pharmacology Division Ri Center Kyoto University
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Kurahashi Kazuyoshi
Pharmacology Division Radioisotope Research Center And Department Of Pharmacology Faculty Of Medicin
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Kurahashi Kazuyoshi
Pharmacology Division Ri Center Kyoto University
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Trandafir Cristina
Pharmacology Division Ri Center Kyoto University
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Nishihashi Tsuyoshi
Pharmacology Division Ri Center Kyoto University
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Shimizu Yoshiharu
Department of Applied Chemistry, School of Advanced Science and Engineering, Waseda University
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