Blocking inducible co-stimulator in the absence of CD28 impairs T_h1 and CD25^+ regulatory T cells in murine colitis
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概要
- 論文の詳細を見る
- 2004-02-01
著者
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De Jong
Division Of Immunology Beth Israel Deaconess Medical Center
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De Jong
Division Of Biomedical Analysis Utrecht University
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TERHORST Cox
Division of Immunology, Beth Israel Deaconess Medical Center, Harvard Medical School
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Gutierrez-ramos Jose-carlos
Inflammation Division Millennium Pharmaceuticals Inc.
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Terhorst Cox
Division Of Immunology Beth Israel Deaconess Medical Center
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Bhan A
Immunopathology Unit Massachusetts General Hospital
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Bhan Atul
Experimental Pathology Massachusetts General Hospital
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Mizoguchi Emiko
Department Of Pathology Harvard Medical School
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Mizoguchi E
Immunopathology Unit Massachusetts General Hospital
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RIETDIJK Svend
Division of Immunology, Beth Israel Deaconess Medical Center
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FAUBION William
Division of Immunology, Beth Israel Deaconess Medical Center
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ABADIA-MOLINA Ana
Division of Immunology, Beth Israel Deaconess Medical Center
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CLARKE Kareem
Division of Immunology, Beth Israel Deaconess Medical Center
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MIZOGUCHI Emiko
Immunopathology Unit, Massachusetts General Hospital
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TIAN Jane
Inflammation Division, Millennium Pharmaceuticals Inc.
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DELANEY Tracy
Inflammation Division, Millennium Pharmaceuticals Inc.
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MANNING Stephen
Inflammation Division, Millennium Pharmaceuticals Inc.
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BHAN Atul
Immunopathology Unit, Massachusetts General Hospital
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COYLE Anthony
Inflammation Division, Millennium Pharmaceuticals Inc.
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Abadia-molina Ana
Division Of Immunology Beth Israel Deaconess Medical Center
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Tian Jane
Inflammation Division Millennium Pharmaceuticals Inc.
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Delaney Tracy
Inflammation Division Millennium Pharmaceuticals Inc.
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Clarke Kareem
Division Of Immunology Beth Israel Deaconess Medical Center
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Rietdijk Svend
Division Of Immunology Beth Israel Deaconess Medical Center
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Coyle Anthony
Inflammation Division Millennium Pharmaceuticals Inc.
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Faubion William
Division Of Immunology Beth Israel Deaconess Medical Center
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Manning Stephen
Inflammation Division Millennium Pharmaceuticals Inc.
関連論文
- Potential pathways for regulation of NK and T cell responses: differential X-linked lymphoproliferative syndrome gene product SAP interactions with SLAM and 2B4
- Activation-induced apoptosis of mature T cells is dependent upon the level of surface TCR but not on the presende of the CD3ζ ITAM
- Generation of antigen-specific cytotoxic T lymphocytes and regulation of cytokine production takes place in the absence of CD3ζ
- Expression of a CD3ε transgene in CD3εnull mice does not restore CD3γ and δ expression bur efficienly rescues T cell development from a subpopulation of prothymocytes
- Over-expression of CD3ε transgenes blocks T lymphocyte development
- Selection of peripheral and intestinal T lymphocytes lacking CD3 ζ
- Regulatory role of B-1 B cells in chronic colitis
- Natural killer cell development is bloked in the context of aberrant T lymphocyte ontogeny
- SAP increases FynT kinase activity and is required for phosphorylation of SLAM and Ly9
- Alteration of a polyclonal to an oligoclonal immune response to cecal aerobic bacterial antigens in TCRα mutant mice with inflammatory bowel disease
- Role of the CD5 molecule on TCR γδ T cell-mediated immune functions: development of germinal centers and chronic intestinal inflammation
- Composition of TCR-CD3 complex in human intestinal intraepithelial lymphocytes: lack of Fc_εRI_γ chain
- The interchain disulfide bond between TCRαβ heterodimers on human T cells is not required for TCR-CD3 membrane expression and signal transduction
- GITR engagement preferentially enhances proliferation of functionally competent CD4^+CD25^+FoxP3^+ regulatory T cells
- Blocking inducible co-stimulator in the absence of CD28 impairs T_h1 and CD25^+ regulatory T cells in murine colitis
- Essential role for Vav1 in activation, but not development, of γδ T cells
- Regulatory role of mature B cells in a murine model of inflammatory bowel disease
- Impaired B cell maturation in mice lacking Bruton's tyrosine kinase (Btk) and CD40
- Analysis of recombinant human growth hormone by capillary electrophoresis with bilayer-coated capillaries using UV and MS detection
- Resistance of activated human T_h2 cells to NO-induced apoptosis is mediated by γ-glutamyltranspeptidase
- Double-positive thymocytes resistant to antigen-MHC-induced negative selection lack active caspase