Age-Related Changes in Serum/Plasma Biochemical Parameters of WHHLMI Rabbits
スポンサーリンク
概要
- 論文の詳細を見る
We developed myocardial infarction-prone rabbits (WHHLMI rabbits) by selectively breeding coronary atherosclerosis-prone WHHL rabbits. To examine the serum/plasma biochemical parameters of this animal model, we assayed the lipid and glucose levels, and enzyme activities of WHHLMI rabbits from 2 to 26 months of age using solid phase analysis. The results showed a good correlation with those measured with a conventional method. The serum enzyme activities and lipid levels varied with aging despite almost no change in the plasma glucose levels. Gender differences were observed in the total cholesterol, triglyceride, and lactate dehydrogenase activity levels. The data on these serum/plasma biochemical parameters will be useful in studies of myocardial infarction or pharmacological studies using this model.
- 社団法人 日本実験動物学会の論文
著者
-
Shiomi Masashi
Institute for experimental animals, Kobe University School of Medicine
-
Shiomi Masashi
Institute For Experimental Animals Kobe University School Of Medicine
-
ITO Takashi
Institute for Experimental Animals, Kobe University School of Medicine
-
Shiomi M
Kobe Univ. School Of Medicine Kobe Jpn
-
Shiomi Masashi
Institute For Experimental Animals Kobe University Graduate School Of Medicine
-
YAMADA Satoshi
Institute for Experimental Animals, Kobe University School of Medicine
-
Yamada Satoshi
Institute For Experimental Animals Kobe University School Of Medicine
-
Yamada Satoshi
Laboratory Of Plant Nutrition Faculty Of Agriculture Hokkaido University
-
Yamada Satoshi
Faculty Of Agriculture Tottori University
-
TAMURA Toshiaki
Institute for Experimental Animals, Kobe University School of Medicine
-
Tamura Toshiaki
Institute For Experimental Animals Kobe University School Of Medicine
-
Shiomi M
Institute For Experimental Animals Kobe University School Of Medicine
-
Yamada S
Fac. Agr. Tottori Univ.
関連論文
- Beneficial Effects of G-CSF on Coronary Atherosclerotic Lesion in Watanabe Heritable Hyperlipidemic Rabbits(Cardiovascular Pharmacology, Basic/Clinical 1 (H), The 69th Annual Scientific Meeting of the Japanese Circulation Society)
- DPJ-048 Can Intravascular Optical Cohenrence Tomography Detect Plaque Erosion? : Some New Findings in Rabbit Models(DPJ08,Intravascular Imagings (I),Digital Poster Session (Japanese),The 73rd Annual Scientific Meeting of The Japanese Circulation Society)
- OE-336 Optical Coherence Tomographic Findings of Macrophage Accumulation in Atherosclerotic Lesions(OE57,Intravascular Imagings (I),Oral Presentation (English),The 73rd Annual Scientific Meeting of The Japanese Circulation Society)
- RhoA and Rac1 Changes in the Atherosclerotic Lesions of WHHLMI Rabbits
- Immunohistochemical and Quantitative Analysis of Cellular and Extra-cellular Components of Aortic Atherosclerosis in WHHL Rabbits
- PJ-216 Receptor for Advanced Glycation End Products (RAGE) Plays a Crucial Role in Atherosclerosis(Atherosclerosis, basic-9, The 71st Annual Scientific Meeting of the Japanese Circulation Society)
- Prominent Lectin-Like Oxidized Low Density Lipoprotein (LDL) Receptor-1 (LOX-1) Expression in Atherosclerotic Lesions Is Associated with Tissue Factor Expression and Apoptosis in Hypercholesterolemic Rabbits(Analytical Biochemistry)
- Distribution Profiles of Membrane Type-1 Matrix Metalloproteinase (MT1-MMP), Matrix Metalloproteinase-2 (MMP-2) and Cyclooxygenase-2 (COX-2) in Rabbit Atherosclerosis : Comparison with Plaque Instability Analysis(Analytical Biochemistry)
- PJ-071 Expression of Lectin-like Oxidized LDL Receptor-1 in Atherosclerotic lesions : Comparison with Tissue Factor Expression and Apoptosis in WHHLMI Rabbits(Atherosclerosis, basic-8, The 71st Annual Scientific Meeting of the Japanese Circulation Society
- PJ-439 Granulocyte Colony-stimulating Factor Ameliorates the Progression of Atherosclerosis(Acute myocardial infarction, basic-4 (IHD) PJ74,Poster Session (Japanese),The 70th Anniversary Annual Scientific Meeting of the Japanese Circulation Society)
- Correlation of Vulnerable Coronary Plaques to Sudden Cardiac Events. Lessons from a Myocardial Infarction-prone Animal Model (the WHHLMI Rabbit)
- Expression of G2A, a Receptor for Lysophosphatidylcholine, by Macrophages in Murine, Rabbit and Human Atherosclerotic Plaques
- IS112 Granulocyte-macrophage colony-stimulating factor alters cellular and extracellular composition of atherosclerotic lesions and reduces atherosclerosis in atherogenic rabbits
- Arteriosclerosis in the Influx and Intravisceral Arteries of the Liver, Kidney and Lung of WHHL Rabbits
- A Rapid PCR Method of Genotyping LDL Receptor Mutations in WHHL Rabbits
- A Novel Approach to Ex Vivo Gene Therapy for Familial Hypercholesterolemia Using Human Amniotic Epithelial Cells as a Transgene Carrier
- Adenosine-Induced Coronary Flow Reserve in Watanabe Heritable Hyperlipidemic Rabbits
- OJ-085 In Vivo Evidence of a Link of Modified LDL to Atherosclerosis Using Capillary Isotachophoresis and Volumetric Intravenous Ultrasound(Lipid disorders(02)(H),Oral Presentation(Japanese),The 72nd Annual Scientific Meeting of the Japanese Circulation S
- Development of the myocardial infarction-prone Watanabe heritable hyperlipidemic rabbit (WHHLMI rabbit) and the usefulness for studies about atherosclerosis
- Discrimination of Recent Ischemic Myocardial Changes in WHHLMI Rabbits from the Findings of Postmortem Degeneration
- Progression of Coronary Atherosclerosis Relates to the Onset of Myocardial Infarction in an Animal Model of Spontaneous Myocardial Infarction (WHHLMI Rabbits)
- Age-Related Changes in Serum/Plasma Biochemical Parameters of WHHLMI Rabbits
- Cholesterol-fed ovariectomized monkeys are good animal models for human atherosclerosis of postmenopausal women
- Decreased Arterial Responses in WHHL Rabbits, an Animal Model of Spontaneous Hypercholesterolemia and Atherosclerosis
- Combined Effects of an 3-Hydroxy-3-Methylglutaryl Coenzyme A Reductase Inhibitor and Angiotensin II Receptor Antagonist on Nitric Oxide Bioavailability and Atherosclerotic Change in Myocardial Infarction-Prone Watanabe Heritable Hyperlipidemic Rabbits
- Some geochemical working standards of marine maganese deposits in the laboratory of mining geology, University of Tsukuba
- Relationships between Root Activity and N, P, K, Ca, and Mg Contents in Roots of Field Crops
- Measurements of Absorption Spectra of Viral Lipids and Proteins in Vacuum-UV Regions with Synchrotron Radiation
- Pathogenesis of tendinous xanthoma : histopathological study of the extremities of Watanabe heritable hyperlipidemic rabbits
- (p,d) Reactions at 52 MeV. : II ^Ni(p,d)^Ni(Analysis)
- (p,d) Reactions at 52 MeV. : I. ^Ni(P,d) ^Ni(Experimental)
- ^22Na^+ and ^36Cl^- Mobility in Salinized Excised Leaves of Several Crop Plants
- ^P Mobility in Detached Leaf of Several Crop Plants
- Effect of Mutual Shading on Carbon Distribution in Rice Plant
- Effect of Sink Manipulation on Nitrogen Accumulation and Distribution among Organs of Gramineae and Leguminosae
- Comparison of Root Growth and Nitrogen Absorbing Ability between Gramineae and Leguminosae during the Vegetative Stage
- Numerical Study and Performance Prediction for Gaseous Hydrogen/Oxygen Bell Nozzle
- Specific Effects of Oxygen Molecule and Plasma on Thin-Film Growth of Y-Ba-Cu-O and Bi-Sr-(Ca)-Cu-O Systems
- Overexpression of a New Rice Vacuolar Antiporter Regulating Protein OsARP Improves Salt Tolerance in Tobacco
- 20-4 Effect of Ca-type Artificial Zeolite on Growth under Saline irrigation in Qatar
- Salt Tolerance of Grain Crops in Relation to Ionic Balance and Ability to Absorb Microelements
- Attenuated liver tumor formation in the absence of CCR2 with a concomitant reduction in the accumulation of hepatic stellate cells, macrophages and neovascularization
- Some characteristics of the zooplankton distribution in the Prydz Bay region of the Indian sector of the Antarctic Ocean in the summer of 1983/84
- Comparison of Sodium Uptake by and Transport in Detached Plant Parts among Several Crops
- Analysis of Gain-Switching Characteristics Including Strong Gain Saturation Effects in Low-Dimensional Semiconductor Lasers
- Adaptive strategy of six native herbaceous species growing over the whole region of Mt. Daisen : characteristics of N, P, K, Ca, and Mg accumulation in leaves(Plant nutrition)
- 突然変異による荷重に対する部分突然変異の役割〔英文〕
- Novel Molecular Imaging of Atherosclerosis With Gallium-68-Labeled Apolipoprotein A-I Mimetic Peptide and Positron Emission Tomography
- Effects of Pravastatin Sodium Alone and in Combination with Cholestyramine on Hepatic, Intestinal and Adrenal Low Density Lipoprotein Receptors in Homozygous Watanabe Heritable Hyperlipidemic Rabbits.
- Novel Molecular Imaging of Atherosclerosis With Gallium-68-Labeled Apolipoprotein A-I Mimetic Peptide and Positron Emission Tomography
- Probucol Suppresses Macrophage Infiltration and MMP Expression in Atherosclerotic Plaques of WHHL Rabbits