血液ガス分析を目的とした積層型微小センシングシステム

概要

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An on-line micro system for the analysis of blood gases was developed. It consists of a reference electrode module and a sensing module with integrated pO2, pCO2, and pH electrodes. The thin-film Ag/AgCl element used in these electrodes features a polyimide protecting layer and AgCl layers grown from pinholes formed in the polyimide layer. The structure was particularly advantageous in constructing the reference electrode module with concentrated internal KCl solution. The electrodes provided linear calibration plots both in batch-style and flow-style measurements. The indicator electrode potential of the pH combination electrode was very close to that obtained with a macroscopic commercial reference electrode. A linear region could be observed in a wide range of partial pressure or pH for the respective electrodes. The output current of the oxygen electrode was slightly affected by flow rate due to the depletion of dissolved oxygen by the electrode reaction. However, the difference was smaller as the flow rate increased. On the other hand, no influence of the flow rate on the other electrodes was observed.
社団法人電気学会の論文
2004-04-01