ヒメダカ(Oryzias latipes)を用いたバイオアッセイによる埋立処分場浸出水の有害性評価

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The ecotoxic effects of leachate from waste disposal landfill sites were studied using Japanese medaka (Oryzias latipes) based on acute lethal toxicity, and the inductions of CYP1A and vitellogenin (Vtg). The leachate exhibited highly lethal toxicity to medaka, however the toxicity was reduced in the leachate treated by biological and chemical processes. These processes seem to decrease the amount of lethally toxic substances from the leachate. CYP1A and Vtg were induced by the leachate and treated water. We also investigated which of the contaminant chemicals detected in the leachate induces CYP1A or Vtg. Multiple regression analysis showed that benzo (g,h,i) perylene causes a significant CYP1A induction among the detected chemicals, but not Vtg induction. The monitoring applications of biomarkers are occasionally more practical for environmental assessment rather than for chemical monitoring, because it is technically impossible to survey all contaminant chemicals, and toxicity data for all chemicals are not available. In our study, not only untreated leachate but also treated leachate is contaminated with estrogenic endocrine disruptors and/or CYP1A inducers, although the lethal toxicity of the treated leachate decreased. This study demonstrated that aquatic environments, where leachate effluents are discharged into, are in danger of endocrine disruptor contamination from waste disposal landfill sites.
社団法人　日本水環境学会の論文
2003-11-10

ヒメダカ(Oryzias latipes)を用いたバイオアッセイによる埋立処分場浸出水の有害性評価

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