High-Affinity Anti-DNA Antibody Parallels Clinical Course of Immunoadsorption Theraphy for Systemic Lupus Erythematosus
スポンサーリンク
概要
- 論文の詳細を見る
Anti-DNA antibody, especially high-affinity anti-DNA antibody (ADNA), is thought to have an important role in the pathogenesis of lupus nephritis. In this study, ADNA which binds to double-stranded DNA under a high concentration of sodium chloride was measured in patients who had received immunoadsorption (IA) therapy with a dextran-sulfate column. Titers of high-affinity ADNA in the cases with renal dysfunction tended to be higher than in those without renal dysfunction. The change in the titer of high-affinity ADNA paralleled the clinical course. These findings suggest that measurement of high-affinity ADNA is useful for follow-up of the clinical course of patients who have undergone IA therapy.(Internal Medicine 35: 367-372, 1996)
- 社団法人 日本内科学会の論文
著者
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Kinoshita Kohji
Third Department Of Internal Medicine Kinki University School Of Medicine
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HORIUCHI ATSUSHI
The Third Department of Internal Medicine, Kinki University School of Medicine
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Enomoto Hiroshi
Third Department Of Internal Medicine Kinki University School Of Medicine
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Ikoma Shinya
The Third Department Of Internal Medicine Kinki University School Of Medicine
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Funauchi Masanori
The Third Department Of Internal Medicine Kinki University School Of Medicine
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Horiuchi Atsushi
The Third Department Of Internal Medicine Kinki University School Of Medicine
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Kurata Noriyuki
The First Department Of Internal Medicine Kagawa Medical University School Of Medicine
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ENOMOTO Hiroshi
the Third Department of Internal Medicine, Kinki University School of Medicine
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OHNO Motoki
the Third Department of Internal Medicine, Kinki University School of Medicine
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KINOSHITA Kohji
the Third Department of Internal Medicine, Kinki University School of Medicine
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Ohno Motoki
The Third Department Of Internal Medicine Kinki University School Of Medicine
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