モルモット啼声反応による疼痛関連行動評価法

概要

論文の詳細を見る
In general, pain has been defined as “an unpleasant sensory and emotional experience associated with actual or potential tissue damage, or described in terms of such damage”, and hence pain is a subjective and emotional experience for each individual. For this reason, it is difficult to study pain in nonverbal animals. However, painful stimuli (noxious stimuli) can cause both a simple and an overt emotional behavior such as self-defense reaction and vocalization in animals. Therefore, we are able to measure these behaviors as nonverbal communication of pain. The vocalization responses is the natural nociceptive reaction of conscious animals and prelingual children. In the present overview, we described the methodology for objective assessment of guinea pigs vocalization response to arterial algogenics and its characteristics.
社団法人日本薬理学会の論文
1998-12-01