Immunohistochemical Study of a Patient with Diffuse Pulmonary Corpora Amylacea Detected by Open Lung Biopsy
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概要
- 論文の詳細を見る
The chest radiographs of an asymptomatic 58-year-old Japanese man with pulmonary corpora aniylacea (PCA) revealed bilateral patchy and nodular infiltrates. Lung specimens obtained by open lung biopsy were histochemically and immunohistochemically analyzed. In all sections of dissected lung tissue, hematoxylin and eosin staining revealed homogeneous eosinophilic acellular round bodies (50-100 μm in diameter) containing granular black pigments in the alveolar spaces. Some round bodies were surrounded and phagocytized by alveolar macrophages. The laminated round bodies stained positively with PAS and Congo red. In addition, many of the rounded bodies contained particles which stained positively with Berlin blue. Immunohistochemical staining for epithelial membrane antigen (EMA) as well as PE-10 was distinctively positive. This is a very rare case of diffuse PCA found by open lung biopsy. Immunohistochemical examination suggested that PCA consisted of pulmonary surfactant protein and epithelial membrane antigen.(Internal Medicine 38: 900-903, 1999)
- 社団法人 日本内科学会の論文
著者
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FUJITA Jiro
the First Department of Internal Medicine, Kagawa Medical University
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Okada Yuhei
Division Of Pathology Matsuyama-shimin Hospital
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TAKAHARA Jiro
The First Department of Internal Medicine
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OHTSUKI Yuji
the Second Department of Pathology
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Yamanouchi Hideo
The Second Department Of Pathology Kochi Medical School
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Fujita Jiro
Department Of Medicine And Therapeutics Control And Prevention Of Infectious Diseases Faculty Of Med
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Fujita Jiro
松山市民病院 臨床病理検査室
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Ohtsuki Y
Division Of Pathology Matsuyama-shimin Hospital
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Takahara J
The First Department Of Internal Medicine Kagawa Medical University
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YOSHINOUCHI Takeo
the Department of Internal Medicine, Matsuyama Shimin Hospital
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Yoshinouchi Takeo
The Department Of Cardiovascular Medicine Matsuyama City Hospital
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WATANABE Ryohei
the Department of Internal Medicine and surgery,Matsuyama-Shimin Hospital
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Yoshinouchi T
Department Of Internal Medicine Toyokawa Municipal Hospital
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Yoshinouchi Takeo
Second Department Of Internal Medicine Medical School Nagoya City University
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Fujita Jiro
Department Of Medicine And Therapeutics Control And Prevention Of Infectious Diseases Faculty Of Med
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Watanabe Ryohei
The Department Of Internal Medicine And Surgery Matsuyama-shimin Hospital
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