Yamada Hiroshi | Worldwide Safety Sciences Pfizer Global Research And Development Nagoya Laboratories Pfizer Japan In

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著作論文

Development of in vitro 3T3 Cell Neutral Red Uptake Phototoxicity Screening System(Test methods, Proceedings of the 32nd Annual Meeting)
CHANGES OF MICRO-RNA EXPRESSION IN RAT LIVER TREATED BY ACETAMINOPHEN OR CARBON TETRACHLORIDE : REGULATING ROLE OF MICRO-RNA FOR RNA EXPRESSION
EVALUATION OF HUMAN HEPATOCYTE CHIMERIC MICE AS A MODEL FOR TOXICOLOGICAL INVESTIGATION USING PANOMIC APPROACHES : EFFECT OF ACETAMINOPHEN ON THE EXPRESSION PROFILES OF PROTEINS AND ENDOGENOUS METABOLITES IN LIVER, PLASMA AND URINE
GENOMIC CLUSTER AND NETWORK ANALYSIS FOR PREDICTIVE SCREENING FOR HEPATOTOXICITY
PHYSICOCHEMICAL AND CELL-BASED APPROACH FOR EARLY SCREENING OF PHOSPHOLIPIDOSIS-INDUCING POTENTIAL
INVESTIGATION OF PROTEOMIC BIOMARKERS IN IN VIVO HEPATOTOXICITY STUDY OF RAT LIVER : TOXICITY DIFFERENTIATION IN HEPATOTOXICANTS
IN VIVO HEPATOTOXICITY STUDY OF RATS IN COMPARISON WITH IN VITRO HEPATOTOXICITY SCREENING SYSTEM
Introduction of the in vivo Mini-tox study as an effective tool to improve confidence in safety in the early stage of drug development (2) Effects of atypical antipsychotics X(Test methods, Proceedings of the 32nd Annual Meeting)
Investigation of protein expression induced by hepatotoxicants in rat hepatocytes cultures and livers(Proceedings of the 32nd Annual Meeting)
Changes of sperm functions and epididymal gene expression in the rats treated with sulfasalazine for several days(Development, Reproduction, Proceedings of the 32nd Annual Meeting)
Effect of aging on QT interval in guinea pigs(Circulatory system, Proceedings of the 32nd Annual Meeting)
PRACTICAL APPLICATION OF GUINEA PIG TELEMETRY SYSTEM FOR QT EVALUATION
EFFECT OF AUTONOMIC NERVOUS FUNCTION ON QT INTERVAL IN DOGS
IDENTIFICATION OF OXIDATIVE STRESS-RELATED PROTEINS FOR PREDICTIVE SCREENING OF HEPATOTOXICITY USING A PROTEOMIC APPROACH
EFFECTS OF MALE REPRODUCTIVE TOXICANTS ON GENE EXPRESSION IN RAT TESTES
PROTEIN EXPRESSION ANALYSIS OF RAT TESTES INDUCED TESTICULAR TOXICITY WITH SEVERAL REPRODUCTIVE TOXICANTS
INVESTIGATION OF A HEPATOTOXICITY SCREENING SYSTEM IN PRIMARY CELL CULTURES : WHAT BIOMARKERS WOULD NEED TO BE ADDRESSED TO ESTIMATE TOXICITY IN CONVENTIONAL AND NEW APPROACHES?
P8-45 Estimation of exposure in toxicology study in discovery stage(BLOOD/TOXICOKINETICS/OTHERS-2)(GENERAL SESSION BY POSTER PRESENTATION)(Proceedings of the 31st Annual Meeting)
P8-34 Usefulness of beam walking test for prediction of adverse effects, "vertigo and dizziness"(STATISTICAL AND TEST METHODS/LOCAL STIMURATION)(GENERAL SESSION BY POSTER PRESENTATION)(Proceedings of the 31st Annual Meeting)
In Vitro Method Investigation for Drugs Induced Vasculitis Evaluation (CIRCULATORY SYSTEM) (GENERAL SESSION BY POSTER PRESENTATION) (Proceedings of the 30th Annual Meeting)
Evaluation of the effects of Sulfasalazine, a male reproductive toxicant, on acrosome reaction in rat sperm.(GENERAL SESSION BY POSTER PRESENTATION)(DEVELOPMENT AND REPRODUCTION)
P7-61 Variation of neurotransmitter contents in the cerebrospinal fluid of conscious dogs(ENDOCRINE AND NERVOUS SYSTEM)(GENERAL SESSION BY POSTER PRESENTATION)(Proceedings of the 31st Annual Meeting)
P7-58 Comparison of the chemicals on open-field activities in rats(ENDOCRINE AND NERVOUS SYSTEM)(GENERAL SESSION BY POSTER PRESENTATION)(Proceedings of the 31st Annual Meeting)
Recovery of cardiovascular parameters in beagle dogs after excitement induced by human contact(Circulatory system, Proceedings of the 32nd Annual Meeting)
P8-22 Effect of autonomic nervous activity on QT interval in dogs(CIRCULATORY SYSTEM-2/ACTIVE OXYGEN)(GENERAL SESSION BY POSTER PRESENTATION)(Proceedings of the 31st Annual Meeting)
P6-14 Development of telemetry system for QT evaluation in guinea pigs(LIVER AND DIGESTIVE SYSTEM/CIRCULATORY SYSTEM-1/DEVELOPMENT AND REPRODUCTION)(GENERAL SESSION BY POSTER PRESENTATION)(Proceedings of the 31st Annual Meeting)
Usefulness of Teflon sonde for oral administration in rats (TEST METHODS) (GENERAL SESSION BY POSTER PRESENTATION) (Proceedings of the 30th Annual Meeting)
P6-20 Usefulness of measuring QT interval with chest lead in Beagle Dogs(LIVER AND DIGESTIVE SYSTEM/CIRCULATORY SYSTEM-1/DEVELOPMENT AND REPRODUCTION)(GENERAL SESSION BY POSTER PRESENTATION)(Proceedings of the 31st Annual Meeting)

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