Horii Ikuo | Worldwide Safety Sciences

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著作論文

P6-38 Relationship between hepatic enzyme induction and carcinogenicity in the p53 deficient mice treated with aminophenylnorharman(DRUG METABOLISM/CARCINOGENICITY)(GENERAL SESSION BY POSTER PRESENTATION)(Proceedings of the 31st Annual Meeting)
Development of in vitro 3T3 Cell Neutral Red Uptake Phototoxicity Screening System(Test methods, Proceedings of the 32nd Annual Meeting)
PHYSICOCHEMICAL AND CELL-BASED APPROACH FOR EARLY SCREENING OF PHOSPHOLIPIDOSIS-INDUCING POTENTIAL
INVESTIGATION OF PROTEOMIC BIOMARKERS IN IN VIVO HEPATOTOXICITY STUDY OF RAT LIVER : TOXICITY DIFFERENTIATION IN HEPATOTOXICANTS
IN VIVO HEPATOTOXICITY STUDY OF RATS IN COMPARISON WITH IN VITRO HEPATOTOXICITY SCREENING SYSTEM
Introduction of the in vivo Mini-tox study as an effective tool to improve confidence in safety in the early stage of drug development (2) Effects of atypical antipsychotics X(Test methods, Proceedings of the 32nd Annual Meeting)
Investigation of protein expression induced by hepatotoxicants in rat hepatocytes cultures and livers(Proceedings of the 32nd Annual Meeting)
Changes of sperm functions and epididymal gene expression in the rats treated with sulfasalazine for several days(Development, Reproduction, Proceedings of the 32nd Annual Meeting)
Comparison between in vitro- and in vivo-hepatotoxicity for the investigation of a hepatotoxicity screening system in primary cell cultures(Liver, Alimentary system, Proceedings of the 32nd Annual Meeting)
PRACTICAL APPLICATION OF GUINEA PIG TELEMETRY SYSTEM FOR QT EVALUATION
EFFECT OF AUTONOMIC NERVOUS FUNCTION ON QT INTERVAL IN DOGS
IDENTIFICATION OF OXIDATIVE STRESS-RELATED PROTEINS FOR PREDICTIVE SCREENING OF HEPATOTOXICITY USING A PROTEOMIC APPROACH
EFFECTS OF MALE REPRODUCTIVE TOXICANTS ON GENE EXPRESSION IN RAT TESTES
PROTEIN EXPRESSION ANALYSIS OF RAT TESTES INDUCED TESTICULAR TOXICITY WITH SEVERAL REPRODUCTIVE TOXICANTS
INVESTIGATION OF A HEPATOTOXICITY SCREENING SYSTEM IN PRIMARY CELL CULTURES : WHAT BIOMARKERS WOULD NEED TO BE ADDRESSED TO ESTIMATE TOXICITY IN CONVENTIONAL AND NEW APPROACHES?
P8-45 Estimation of exposure in toxicology study in discovery stage(BLOOD/TOXICOKINETICS/OTHERS-2)(GENERAL SESSION BY POSTER PRESENTATION)(Proceedings of the 31st Annual Meeting)
P8-34 Usefulness of beam walking test for prediction of adverse effects, "vertigo and dizziness"(STATISTICAL AND TEST METHODS/LOCAL STIMURATION)(GENERAL SESSION BY POSTER PRESENTATION)(Proceedings of the 31st Annual Meeting)
P7-24 Investigation of the hepato-toxicity screening system in primary cell culture(IMMUNE AND ALLERGIC SYSTEM/KIDNEYS AND URINARY EXCRETION SYSTEM/CYTOTOXICITY/OTHERS-1)(GENERAL SESSION BY POSTER PRESENTATION)(Proceedings of the 31st Annual Meeting)
P6-46 Effect of reproductive toxicants on the protein expression in the rat testis(TOXICOGENOMICS)(GENERAL SESSION BY POSTER PRESENTATION)(Proceedings of the 31st Annual Meeting)
P6-45 Effect of reproductive toxicants on the gene expression in the testes of rats(TOXICOGENOMICS)(GENERAL SESSION BY POSTER PRESENTATION)(Proceedings of the 31st Annual Meeting)
Effects of sulfasalazine on gene expressions in testis and epididymis (TOXICOGENOMICS AND TOXICOPROTEOMICS) (GENERAL SESSION BY POSTER PRESENTATION) (Proceedings of the 30th Annual Meeting)
Method for RNA Extraction from Formalin-Fixed, Paraffin-Embedded Tissues(Test methods, Proceedings of the 32nd Annual Meeting)
P7-45 Usefulness of fecal occult blood kits by the immunity method : Examination in rats and dogs(GENERAL TOXICITY)(GENERAL SESSION BY POSTER PRESENTATION)(Proceedings of the 31st Annual Meeting)
MECHANISM FOR SHORTENING PT AND APTT IN DOGS AND RATS : EFFECT OF FIBRINOGEN ON PT AND APTT
Measurements for rat and canine D-dimer in plasma using human clinical latex agglutination reagents (BLOOD SYSTEM) (GENERAL SESSION BY POSTER PRESENTATION) (Proceedings of the 30th Annual Meeting)
P7-61 Variation of neurotransmitter contents in the cerebrospinal fluid of conscious dogs(ENDOCRINE AND NERVOUS SYSTEM)(GENERAL SESSION BY POSTER PRESENTATION)(Proceedings of the 31st Annual Meeting)
P7-58 Comparison of the chemicals on open-field activities in rats(ENDOCRINE AND NERVOUS SYSTEM)(GENERAL SESSION BY POSTER PRESENTATION)(Proceedings of the 31st Annual Meeting)
Evaluation of QT interval with telemetry system in conscious guinea pigs (CIRCULATORY SYSTEM) (GENERAL SESSION BY POSTER PRESENTATION) (Proceedings of the 30th Annual Meeting)
Usefulness of Teflon sonde for oral administration in rats (TEST METHODS) (GENERAL SESSION BY POSTER PRESENTATION) (Proceedings of the 30th Annual Meeting)
BLOOD COAGULATION TESTS IN TOXICOLOGICAL STUDIES : REVIEW OF METHODS AND THEIR SIGNIFICANCE FOR DRUG SAFETY ASSESSMENT
P8-47 Investigation of environmental influences on the behavioral observation of rats(BLOOD/TOXICOKINETICS/OTHERS-2)(GENERAL SESSION BY POSTER PRESENTATION)(Proceedings of the 31st Annual Meeting)
P8-33 Validation of an in vitro screening assay for phospholipidosis in drug development(STATISTICAL AND TEST METHODS/LOCAL STIMURATION)(GENERAL SESSION BY POSTER PRESENTATION)(Proceedings of the 31st Annual Meeting)

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