Horii Ikuo | Department Of Preclinical Science Nippon Roche K. K. Research Center

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Toxicological assessment of a novel anti-tumor agent Capecitabine (Ro 09-1978, 5'-DFCR derivative : Species differences and improvement of intestinal toxicity
Toxicological assessment of a novel anti-tumor agent Capecitabine (Ro 09-1978, 5'-DFCR derivative) : Toxicokinetics in monkeys, rats and mice
ASSESSMENT OF QUANTITATIVE DUAL-PARAMETER FLOW CYTOMETRIC ANALYSIS FOR THE EVALUATION OF TESTICULAR TOXICITY USING CYCLOPHOSPHAMIDE -AND ETHINYLESTRADIOL- TREATED RATS
FLOW CYTOMETRIC ANALYSIS FOR SPERM VIABILITY AND COUNTS IN RATS TREATED WITH TRIMETHYLPHOSPHATE OR PYRIDOXINE
Flow cytometric analysis of sperm viability and number in the rats treated with Trimethylphosphate and Ornidazole.
CHALLENGE TO IN VITRO ANTIGENICITY STUDY IN HUMAN LYMPHOCYTES : ESTABLISHMENT OF TEST SYSTEM USING HETEROGENEOUS PROTEINS AS ANTIGENS
MALE FERTILITY IN RATS TREATED WITH ETRETINATE FOR 4 WEEKS (<SPECIAL ISSUE>TESTICULAR TOXICITY)
EFFECT OF ETRETINATE (AROMATIC RETINOID) TREATMENT DURING GESTATION AND LACTATION PERIODS ON VIABILITY AND SOMATIC GROWTH IN F1 RATS
EFFECT OF 1,25-DIHYDROXYVITAMIN D_3 ON THE FEMALE REPRODUCTIVE SYSTEM IN RATS
"A-12 Investigation of SCID mice transferred with human lymphocytes (hu-PBL-SCID mice) for the evaluation of toxicity on human immune system. : Human immunoglobulin production in hu-PBL-SCID mice
P-80 Comparative 4 AND 2 Weeka Oral Repeated Dosing Studies On Male Reproductive Organs in Rats Treated With 5-Fluorouracil.(Proceedings of the 27th Annual Meeting)
COLLABORATIVE WORK TO EVALUATE TOXICITY ON MALE REPRODUCTIVE ORGANS BY REPEATED DOSE STUDIES IN RATS : 18)COMPARATIVE 4 AND 2 WEEKS ORAL REPEATED DOSING STUDIES ON MALE REPRODUCTIVE ORGANS IN RATS TREATED WITH 5-FLUOROURACIL
COMPARATIVE TOXICOLOGICAL ASSESSMENT OF A WATER-SOLUBLE AZOLE ADMINISTERED BOTH ORALLY AND BY INTRAVENOUS CONTINUOUS INFUSION IN CYNOMOLGUS MONKEYS
TOXICOKINETICS:ITS SIGNIFICANCE AND PRACTICAL PROBLEMS
EFFECTS OF DOXIFLURIDINE(DFUR)ON MOUSE THYMOCYTE DIFFERENTIATION
Report 3 : FUTURE PROSPECTS FOR TOXICOKINETICS : ITS ABILITY TO PREDICT DRUG ADVERSE EVENTS IN HUMANS (TOXICOKINETICS)
COMPARATIVE IMMUNOTOXICITY ASSESSMENT OF N^4-TRIMETHOXYBENZOYL-5'-DEOXY-5-FLUOROCYTIDINE (RO 09-1390) AND 5'-DEOXY-5-FLUOROURIDINE (5'-DFUR) IN BDF1 MICE
2B-22 Homologous passive cutaneous anaphylaxis test in mice
Inhibitory effect of endothelin receptor antagonist on growth of 3T3-E1 osteoblastic cells in vitro.
AROMATIC RETINOID RO 40-8757 REDUCES IMMUNOTOXICITIES OF CYCLOPHOSPHAMIDE AS REVEALED BY IMMUNOHISTOCHEMICAL STAINING OF LYMPHOID TISSUES AND GENERAL PATHOLOGIC EXAMINATIONS
Investigation of in vitro antigenicity study by using dendritic cells induced from mouse bone marrow cells. Expression of cell surface markers by exposure to antigens.(GENERAL SESSION BY ORAL PRESENTATION)(IMMUNE AND ALLERGIC SYSTEM)
ENDOCRINOLOGICAL ASSESSMENT OF TOXIC EFFECTS ON THE MALE REPRODUCTIVE SYSTEM IN RATS TREATED WITH 5-FLUOROURACIL FOR 2 OR 4 WEEKS
O12-14 Significant endocrinological parameters for the assessment of male reproductive toxicity induced by 1, 3-Dinitrobenzene or Taxol
6-Mercaptopurine-induced histopathological changes and xanthine oxidase expression in rat placenta

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