中村 紳一郎 | Specialty Chemicals Research Center Shin-etsu Chemical Co. Ltd.
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概要
関連著者
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中村 紳一郎
Specialty Chemicals Research Center Shin-etsu Chemical Co. Ltd.
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Nakamura S
Specialty Chemicals Research Center Shin-etsu Chemical Co. Ltd.
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Nakamura Satoko
Osaka University Of Pharmaceutical Sciences
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Narimatsu Shizuo
Department Of Hygienic Chemistry Faculty Of Pharmaceutical Sciences Hokuriku University
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Yamamoto Ikuo
北陸大学 薬 衛化
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Nakamura S
Laboratories Of Health Chemistry Graduate School Of Medicine Dentistry And Pharmaceutical Sciences O
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Narimatsu Shizuo
Laboratories Of Health Chemistry Graduate School Of Medicine Dentistry And Pharmaceutical Sciences O
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NAKAMURA Seikou
Kyoto Pharmaceutical University
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Nakamura S
Toyama Univ. Toyama Jpn
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Watanabe Kazuhito
Faculty Of Pharmaceutical Sciences Kyushu University
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Yamamoto Ikuo
Department Of Hygienic Chemistry Faculty Of Pharmaceutical Sciences Hokuriku University
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Yoshimura Hidetoshi
Department Of Food And Nutrition Nakamura Gakuen University
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Yoshimura Hidetoshi
Department Of Food And Nutrition Nakamura Gakuen
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YAMAMOTO IKUO
Department of Laboratory Medicine, Miyazaki Medical College
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YOSHIMURA Hidetoshi
Department of Food and Nutrition, Nakamura Gakuen University
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NARIMATSU SHIZUO
School of Pharmacy, Hokuriku University
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Yamamoto Ikuo
School Of Pharmaceutical Sciences Kyushu University Of Health And Welfare
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WATANABE KAZUHITO
School of Pharmacy, Hokuriku University
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YAMAMOTO Ikuo
School of Pharmaceutical Sciences, Kyushu University of Health and Welfare
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Yoshimura Hidetoshi
Faculty Of Pharmaceutical Sciences Kyushu University
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NARIMATSU SHIZUO
Departments of Hygienic Chemistry
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Watanabe Kazuhito
Department Of Chemistry And Chemical Engineering Faculty Of Engineering Yamagata University
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YOSHIMURA HIDETOSHI
Faculty of Pharmaceutical Sciences, Kyushu University
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Watanabe Kazuhito
Department of Hygienic Chemistry, Faculty of Pharmaceutical Sciences, Hokuriku University
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FUNAE Yoshihiko
Osaka City University School of Medicine
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Funae Y
Osaka City Univ. Medical School Osaka Jpn
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Funae Y
Osaka City University Medical School
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Funae Yoshihiko
Department Of Chemical Biology Osaka City University Medical School
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Imaoka S
Nanobiotechnology Research Center And Department Of Bioscience School Of Science And Technology Kwan
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Imaoka Susumu
Department Of Bioscience And Nanobiotechnology Research Center School Of Science And Technology Kwan
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SHIBANO Makio
Osaka University of Pharmaceutical Sciences
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KUSANO Genjiro
Osaka University of Pharmaceutical Sciences
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Shibano M
Osaka University Of Pharmaceutical Sciences
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Kusano G
Osaka University Of Pharmaceutical Sciences
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Kusano Genjiro
Osaka University Of Phamaceutical Sciences
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FUNAE Yoshihiko
Department of Chemical Biology, Osaka City University Graduate School of Medicine
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TSUKADA SHIRO
Departments of Environmental Science
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ITOH MAKOTO
Hygienic Chemistry
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YAMAMOTO IKUO
Hygienic Chemistry
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YOSHIMURA HIDETOSHI
School of Pharmacy, Hokuriku University
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SHIMONISHI TATSUYUKI
School of Pharmacy, Hokuriku University
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Funae Yoshihiko
Department Of Chemical Biology Osaka City University Graduate School Of Medicine
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Gohda H
Hokuriku Univ. Kanazawa Jpn
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Hamajima Koichi
School Of Pharmacy Hokuriku University
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Tsukada Shiro
北陸大学 薬
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Matsubara Kazuhiko
School Of Pharmacy Hokuriku University
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Demura R
The Department Of Medicine
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Itoh Makoto
School Of Pharmacy Hokuriku University
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小久保 宏恭
Specialty Chemicals Research Center Shin-etsu Chemical Co. Ltd.
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砂田 久一
Faculty Of Pharmacy Meijo University
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Wakusawa Shinya
愛知学院大学 薬学部薬物治療学
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Wakusawa Shinya
Department Of Medical Technology Nagoya University School Of Health Sciences
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Wakusawa Shinya
Faculty Of Pharmaceutical Sciences Hokuriku University
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Takahashi K
Faculty Of Pharmaceutical Sciences Hoshi University
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FUNAE Yoshihiko
Laboratory of Chemistry, Osaka City University Medical School
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Miyamoto K
Department Of Hospital Pharmacy School Of Medicine Kanazawa University:department Of Medicinal Infor
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Yamamoto Ikuo
Faculty of Education, Yokohama National University
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NARIMATSU Shizuo
Faculty of Pharmaceutical Sciences, Okayama University
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MATSUNAGA Tamihide
Department of Pharmacy, Shinshu University Hospital
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MIYAMOTO Ken-ichi
Faculty of Pharmaceutical Science
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WATANABE Kazuhito
Faculty of Pharmaceutical Sciences, Hokuriku University
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MATSUNAGA Tamihide
Faculty of Pharmaceutical Sciences, Hokuriku University
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Takahashi K
School Of Pharmaceutical Sciences Kitasato University
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GOHDA Hiroshi
Department of Hygienic Chemistry, School of Pharmacy, Hokuriku University
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IMAOKA Susumu
Department of Hygienic Chemistry, School of Pharmacy, Hokuriku University
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ARAI MAYUMI
School of Pharmacy, Hokuriku University
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HAMAJIMA KOICHI
School of Pharmacy, Hokuriku University, Kanazawa
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SHIMONISHI TATSUYUKI
Department of Hygienic Chemistry, School of Pharmacy, Hokuriku University
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Takahashi Kenji
Research Laboratories, Kyoto Pharmaceutical Industries, Ltd.
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Kasai Masayasu
Research Laboratories, Kyoto Pharmaceutical Industries, Ltd.
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Kanda Mamoru
Research Laboratories, Kyoto Pharmaceutical Industries, Ltd.
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Shirahase Hiroaki
Research Laboratories, Kyoto Pharmaceutical Industries, Ltd.
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Funae Yoshihiko
Laboratory Of Chemistry Osaka City University
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MATSUI Hiroshi
Research Institute for Scientific Measurements, Tohoku University
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Kanda Mamoru
Research Laboratories Kyoto Pharmaceutical Industries Ltd.
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Narimatsu Shizuo
Faculty Of Pharmaceutical Sciences Okayama University
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Watanabe Kazuhito
Department Of Hygienic Chemistry Faculty Of Pharmaceutical Sciences Hokuriku University
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Shirahase Hiroaki
Research Laboratories Kyoto Pharmaceutical Industries Ltd.
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Shirahase Hiroaki
Research Laboratories Kyoto Pharmaceutical Company Ltd.
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Kurahashi Kazuyoshi
Research Laboratories Kyoto Pharmaceutical Industries Ltd.
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Kunishiro Kazuyoshi
Research Laboratories Kyoto Pharmaceutical Industries Ltd.
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Kamiya Shoji
Research Laboratories Kyoto Pharmaceutical Industries Ltd.
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NAKAMURA Shohei
Research Laboratories, Kyoto Pharmaceutical Industries, Ltd.
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YOSHIMI Akihisa
Research Laboratories, Kyoto Pharmaceutical Industries, Ltd.
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KURAHASHI Kazuyoshi
Pharmacology Division, Radioisotope Research Center, Kyoto University
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Arai Mayumi
School Of Pharmacy Hokuriku University:faculty Of Pharmaceutical Sciences Kyushu University
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Kamiya S
Research Laboratories Kyoto Pharmaceutical Industries Ltd.
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Nakamura Shohei
Research Laboratories Kyoto Pharmaceutical Industries Ltd.
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Kanda M
Research Laboratories Kyoto Pharmaceutical Industries Ltd.
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Yoshimi A
Research Laboratories Kyoto Pharmaceutical Industries Ltd.
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Shirahase H
Research Laboratories Kyoto Pharmaceutical Industries Ltd.
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AKAZAWA Naomi
Osaka University of Pharmaceutical Sciences
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Watanabe Kazuhito
Faculty Of Pharmaceutical Sciences Hokuriku University
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Matsunaga Tamihide
Faculty Of Pharmaceutical Sciences Kyushu University
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Yoshimi Akihisa
Research Laboratories Kyoto Pharmaceutical Industries Ltd.
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Miyamoto Ken-ichi
Faculty Of Industrial Science And Technology Science University Of Tokyo
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Matsunaga Tamihide
Department Of Pharmacy Shinshu University Hospital
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Kurahashi Kazuyoshi
Pharmacology Division Radioisotope Research Center And Department Of Pharmacology Faculty Of Medicin
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Wakusawa Shinya
Department Of Radiological And Medical Laboratory Sciences
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Matsui H
Yamaguchi Univ. Hospital Ube Jpn
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NIWA Toshiro
Department of Chemical Biology, Osaka City University Graduate School of Medicine
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OKADA Kazushi
Department of Chemical Biology, Osaka City University Graduate School of Medicine
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HIROI Toyoko
Department of Chemical Biology, Osaka City University Graduate School of Medicine
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IMAOKA Susumu
Nanobiotechnology Research Center and Department of Bioscience, School of Science and Technology, Kw
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NARIMATSU Shizuo
Laboratories of Health Chemistry,Graduate School of Medicine, Dentistry and Pharmaceutical Sciences,
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ITOH Makoto
Department of Internal Medicine and Bioregulation, Nagoya City University Medical School
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伊藤 喬
昭和大学薬学部
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景山 節
京大・霊長類研・生化学
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KOTANI Noriko
Department of Geriatric Medicine, Osaka University Graduate School of Medicine
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奥山 和典
Kyoto Pharmaceutical University
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伊藤 喬
昭和大学薬学部薬化学教室
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Yamazaki Mami
Department Of Molecular Biology And Biotechnology Graduate School Of Pharmaceutical Sciences Chiba U
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Yamamoto Ikuo
Department Of Hygienic Chemistry School Of Pharmaceutical Sciences Kyushu University Of Health And W
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Nomura Masaaki
北陸大学 薬学部臨床薬理学
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Nomura Masaaki
北陸大学 薬学部合成化学
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Kimura Toshiyuki
Department of Hygienic Chemistry, Faculty of Pharmaceutical Sciences, Hokuriku University
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IMAOKA Susumu
Laboratory of Chemistry, Osaka City University Medical School
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Miyamoto K
Kanazawa Univ Kanazawa
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Nomura Masaaki
Department Of Clinical Pharmacology Faculty Of Pharmaceutical Sciences Hokuriku University
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Itoh Makoto
Department Of Cardiology Yamagata General Nihonkai Hospital
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Itoh T
Graduate School Of Pharmaceutical Sciences Osaka University
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Itoh Takuya
Graduate School Of Pharmaceutical Sciences Osaka University
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Hiroi Toyoko
Department Of Chemical Biology Osaka City University Graduate School Of Medicine
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Itoh Tatsuya
Faculty Of Pharmaceutical Sciences Hokuriku University
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Okada Kazushi
Department Of Chemical Biology Osaka City University Graduate School Of Medicine:nanobiotechnology R
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Kotani Noriko
Department Of Geriatric Medicine Osaka University Graduate School Of Medicine
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Kotani Noriko
Departments Of Environmental Hygiene School Of Pharmacy Hokuriku University
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Yokota M
School Of Pharmaceutical Sciences Showa University
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Nomura Masaaki
Faculty Of Pharmaceutical Sciences Hokuriku University
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Kitagawa S
Niigata Univ. Pharmacy And Applied Life Sci. Niigata Jpn
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Kitagawa Shuji
Kobe Pharmaceutical University
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Kitagawa S
Niigata College Of Pharmacy
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Nagata K
School Of Pharmaceutical Sciences Showa University
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HO Ing
University of Mississippi Medical Center
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HO Ing
Department of Pharmacology and Toxicology, University of Mississippi Medical Center
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NAKAMURA Shizuko
Department of Hygienic Chemistry, Faculty of Pharmaceutical Sciences, Hokuriku University
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MINOURA Katsuhiko
Osaka University of Pharmaceutical Sciences
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OGURI Kazuta
Faculty of Pharmaceutical Sciences, Kyushu University
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SUZUKI NORIYOSHI
College of Medical Science, Tohoku University
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TSUKADA SHIRO
Environmental Hygiene
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DEMURA REIKO
Environmental Hygiene
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ITOH MAKOTO
School of Pharmacy, Hokuriku University
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MATSUBARA KAZUHIKO
School of Pharmacy, Hokuriku University
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MATSUBARA KAZUHIKO
Department of Hygienic Chemistry, School of Pharmacy, Hokuriku University
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Kimura T
Department Of Hygienic Chemistry Faculty Of Pharmaceutical Sciences Hokuriku University
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Miyazaki Michiko
School of Pharmaceutical Sciences, Showa University
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Nagata Kazuhiro
School of Pharmaceutical Sciences, Showa University
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Itoh Takashi
School of Pharmaceutical Sciences, Showa University
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Yokota Masashi
School of Pharmaceutical Sciences, Showa University
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Kameoka Keiko
School of Pharmaceutical Sciences, Showa University
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Nakamura Shigeru
School of Pharmaceutical Sciences, Showa University
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Ohsawa Akio
School of Pharmaceutical Sciences, Showa University
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NAKAMURA Shigeo
Faculty of Pharmaceutical Sciences, Kyoritsu College of Pharmacy
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景山 節
京都大学霊長類研究所人類進化モデル研究センター
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景山 節
京大・霊長研
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Ho Ing
ミシシッピ大学医学部薬毒理学教室
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NAKAMURA Shigeo
Fujiyakuhin Co., Ltd.,
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MINAMINO Tomoyoshi
Faculty of Pharmaceutical Sciences, Hokuriku University
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HIDAKA Hiroyoshi
Nagoya University School of Medicine
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Kimura Toshiyuki
Department Of Hygienic Chemistry Faculty Of Pharmaceutical Sciences Hokuriku University
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Miyazaki Makoto
Department Of Pharmaceutics Osaka University Of Pharmaceutical Sciences
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Hidaka Hiroyoshi
Nagoya Univ. Sch. Of Medicine
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Narimatsu Shizuo
Laboratories Health Chemistry Faculty Of Pharmaceutical Sciences Okayama University
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Yoshimura Hidetoshi
Faculty Of Pharmaceutical Sciences Kyushu University(present):department Of Food And Nutrition Nakam
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Imaoka Susumu
Nanobiotechnology Res. Center And Dep. Of Bioscience School Of Sci. And Technol. Kwansei Gakuin Univ
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Imaoka Susumu
Laboratory Of Chemistry Osaka City University
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Nakamura Shigeo
Faculty Of Pharmaceutical Sciences Kyoritsu University Of Pharmacy
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Kimura T
Department Of Medicinal Chemistry Center For Frontier Research In Medicinal Science 21st Century Coe
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Oguri Kazuta
Faculty Of Pharmaceutical Sciences Kyushu University
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Oguri Kazuta
School Of Pharmacy Hokuriku University
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OHTA Shunsaku
Kyoto Pharmaceutical University
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KAWASAKI Ikuo
Kyoto Pharmaceutical University
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YAMASHITA Masayuki
Kyoto Pharmaceutical University
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Niwa Toshiro
Department Of Chemical Biology Osaka City University Graduate School Of Medicine
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川崎 郁勇
Department Of Functional Molecular Chemistry Kyoto Pharmaceutical University:school Of Pharmaceutica
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Ho Ing
Department Of Pharmacology & Toxicology University Of Mississippi Medical Center
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MOTOYA Naomi
Osaka University of Pharmaceutical Sciences
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Ohta S
Department Of Functional Molecular Chemistry Kyoto Pharmaceutical University
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Ohsawa A
School Of Pharmaceutical Sciences Showa University
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Ohsawa Akio
School Of Pharmaceutical Sciences Showa University
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Kameoka Keiko
School Of Pharmaceutical Sciences Showa University
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Yoshida H
Lab. Of Food & Nutritional Sciences Dep. Of Nutritional Sci. Kobe-gakuin Univ.
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Yokoya M
Chiba Univ. Chiba Jpn
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OKUYAMA Kazunori
Kyoto Pharmaceutical University
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NAGAMINE Rumiko
Kyoto Pharmaceutical University
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TSUJITA Takako
Kyoto Pharmaceutical University
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Yoshimura H
Faculty Of Pharmaceutical Sciences Kyushu University(present):department Of Food And Nutrition Nakam
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KUBORI Masami
Osaka University of Pharmaceutical Sciences
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KITAGAWA Satoshi
Osaka University of Pharmaceutical Sciences
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Yamamoto I
Hygienic Chemistry
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Yoshida Hiromi
Department Of Nutritional Science Kobe Gakuin University
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Minanmino Tomoyoshi
Department Of Legal Medicine Kanazawa University School Of Medicine
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Kokubo H
Shin‐etsu Chemical Co. Ltd. Niigata Jpn
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Suzuki Noriyoshi
College Of Medical Science Tohoku University
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Yamashita Masayuki
Kyoto Pharmaceutical Univ. Kyoto Jpn
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Sunada H
Faculty Of Pharmacy Meijo University
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Sunada Hisakazu
Fac. Of Pharmacy Meijo Univ.
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Noguchi Masamichi
Department Of Clinical Pharmacology Faculty Of Pharmaceutical Sciences Hokuriku University
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Yamamoto Ikuo
Hygienic Chemistry School Of Pharmacy Hokuriku University
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永田 和弘
School Of Pharmaceutical Sciences Showa University
著作論文
- Effect of Psychotropic Drugs on the 21-Hydroxylation of Neurosteroids, Progesterone and Allopregnanolone, Catalyzed by Rat CYP2D4 and Human CYP2D6 in the Brain(Biochemistry)
- Effect of Several Cellulosic Binders on Particle Size Distribution in Fluidized Bed Granulation
- Effect of Several Cellulosic Binders on Particle Size Distribution of Granules Prepared by a High-Speed Mixer
- Pharmacologica Efects in Mice of Anandamide and Its Related Fatty Acid Ethanolamides, and Enhancement of Cataleptogenic Effect of Anandamide by Phenylmethylsulfonyl Fluoride
- Determination of Heavy Metal Contents in Human Gallstones Using X-Ray Fluorescence Spectrometry (Regular Presentations) (Proceedings of the 15 th Symposium on Environmental Pollutants and Toxicology)
- Determination of Metal Contents in River Sediment Near a Closed Mine by X-ray Fluorescence Spectrometry (Proceedings of the 14th Symposium on Environmental Pollutants and Toxicology)
- Determination of Metal Contents in Biological and Environmental Materials by Energy-Dispersive X-Ray Fluorescence Analysis
- MECHANISM OF SLEEP-PROLONGATING EFFECT OF Δ^8-TETRAHYDROCANNABINOL (Δ^8-THC) AND ITS METABOLITES
- Mechanism of Hepatic Microsomal Oxidation of 11-Hydroxy-Δ^8-tetra-hydrocannabinol to 11-Oxo-Δ^8-tetrahydrocannabinol. Evidence for Hydration of the Aldehyde Formed
- INTERACTION OF CANNABINOIDS WITH HEPATIC MICROSOMAL DRUG-METABOLIZING ENZYME SYSTEM IN THE RAT
- PURIFICATION AND CHARACTERIZATION OF MOUSE HEPATIC MICROSOMAL ALDEHYDE OXYGENASE
- MECHANISM OF CANNABIELSOIN FORMATION FROM CANNABIDIOL, ONE OF THE MAJOR CMPONENTS OF MARIHUANA
- CYTOCHROME P450 ISOZYMES INVOLVED IN METABOLIC ACTIVATION OF Δ^9-TETRAHYDROCANNABINOL BY RAT LIVER MICROSOMES
- Mechanism of Biological Formation of Cannabielsoin from Cannabidiol in the Guinea-Pig, Mouse, Rat and Rabbit
- HEPATIC MICROSOMAL OXYGENATION OF METHYL GROUP TO CARBOXYLIC ACID IN XENOBIOTICS : METABOLISM OF Δ^8-TETRAHYDROCANNABINOL AT THE 11-POSITION
- Identification of Cannabielsoin, a New Metabolite of Cannabidiol Formed by Guinea-Pig Hepatic Microsomal Enzymes, and Its Pharmacological Activity in Mice
- IN VIVO EFFECTS OF TETRAHYDROCANNABINOLS AND THEIR EIGHT MONOOXYGENATED METABOLITES ON THE HEPATIC MICROSOMAL DRUG-METABOLIZING ENZYME SYSTEMS OF MICE
- METABOLIC ACTIVATION OF CANNABIDIOL BY HEPATIC MICROSOMES. COMPLEX FORMATION WITH CYTOCHROME P-450
- MECHANISM OF THE PROLONGATION OF BARBITURATE-INDUCED SLEEPING TIME AND THE INHIBITION OF THE HEPATIC MICROSOMAL DRUG METABOLIZING ENZYMES BY CANNABIDIOL, A COMPONENT OF CANNABIS
- EFFECTS OF TWO CANNABINOIDS ON HEPATIC MICROSOMAL CYTOCHROME P-450
- METABOLIC ACTIVATION OF Δ^8-THTRAHYDROCANNABINOL (Δ^8-THC) AT THE 7-POSITION AND MECHANISM OF THE OXIDATION OF 7-HYDROXY-Δ^8-THC TO 7-OXO-Δ^8-THC WITH LIVER MICROSOMES
- METABOLIC DISPOSITION OF 8α, 9α-AND 8β, 9β-EPOXYHEXAHYDROCANNABINOLS IN THE MOUSE
- IN VITRO METABOLISM OF TETRAHYDROCANNABINOL (THC) BY HUMAN LIVER MICROSOMES. EPOXIDE-DIOL PATHWAY OF THC
- DIFFERENCE IN EPOXIDES FORMATION AND THEIR FURTHER METABOLISM BETWEEN Δ^9 -AND Δ^8-TETRAHYDROCANNABINOLS BY HUMAN LIVER MICROSOMES
- The Synthesis of Isoquinoline Alkaloid and Its Related Compounds Using Alanine Derivatives as Chiral Auxiliaries
- Establishment by Adriamycin Exposure of Multidrug-resistant Rat Ascites Hepatoma AH130 Cells Showing Low DT-diaphorase Activity and High Cross Resistance to Mitomycins
- Inhibition of P-Glycoprotein-Dependent Multidrug Resistance by an Isoquinolinesulfonamide Compound H-87 in Rat Ascites Hepatoma AH66 Cells
- A Novel Series of Thromboxane A_2 Synthetase Inhibitors with Free Radical Scavenging and Anti-peroxidative Activities
- Bioavailable Acyl-CoA : Cholesterol Acyltransferase Inhibitor with Anti-peroxidative Activity : Synthesis and Biological Activity of Novel Indolinyl Amide and Urea Derivatives
- Studies on the Constituents of Broussonetia Species. V. Two New Pyrrolidine Alkaloids, Broussonetines K and L, as Inhibitors of Glycosidase, from Broussonetia Kazinoki SIEB.
- Reductive Dimerization of Alkylidenemalonates Using Samarium(II) Diiodide and ^1H-NMR Behavior of the Dimers, 2,3-Diaryl-1,1,4,4-butanetetracarboxylates
- INHIBITORY EFFECT OF CANNABIDIOL ON THE HEPATIC MICROSOMAL DRUG-METABOLIZING ENZYME SYSTEM IN THE RAT
- Studies on the Constituents of Broussonetia Species. IV. Two New Pyrrolidinyl Piperidine Alkaloids, Broussonetines I and J, from Broussonetia kazinoki SIEB.
- Studies on the Constituents of Broussonetia Species. III. Two New Pyrrolidine Alkaloids, Broussonetines G and H, as Inhibitors of Glycosidase, from Broussonetia kazinoki SIEB.
- Studies on the Constituents of Broussonetia Species. II. Six New Pyrrolidine Alkaloids, Broussonetine A, B, E, F and Broussonetinine A and B, as Inhibitors of Glycosidases from Broussonetia kazinoki SIEB.
- TOLERANCE DEVELOPMENT TO HYPOTHERMIC EFFECT OF Δ^8-TETRAHYDROCANNABINOL AND ITS ACTIVE METABOLITES
- METABOLIC DISPOSITION OF 8α, 9α- AND 8β, 9β-EPOXYHEXAHYDROCANNABINOL (EHHC) IN THE MOUSE
- 9α, 10α-EPOXYHEXAHYDROCANNABINOL FORMATION FROM Δ^9-TETRAHYDROCANNABINOL BY LIVER MICROSOMES OF PHENOBARBITAL-TREATED MICE AND ITS PHARMACOLOGICAL ACTIVITIES IN MICE
- IN VITRO METABOLIC FORMATION OF 8α, 9α-EPOXYHEXAHYDROCANNABINOL AND ITS IMPLICATION IN THE PHARMACOLOGICAL ACTIVITY OF Δ^8-TETRAHYDROCANNABINOL