Sensitive Fluorescence Microscopy of Neurons Cultured on a Plasmonic Chip
スポンサーリンク
概要
- 論文の詳細を見る
A plasmonic chip with a periodic structure coated with thin metal films was fabricated and applied to bioimaging under a fluorescence microscope. By using the enhanced electric field of surface plasmon resonance excited on the chip, an enhanced fluorescence of samples was observed by conventional fluorescence microscopy. In this study, neurons were cultured on a plasmonic chip, which was used instead of a glass-bottomed dish or cover glass; the received fluorescence images of neuron dendrites were more than four times brighter than those obtained from similar specimens cultured on a glass-bottomed dish and observed using an upright fluorescence microscope.
- 2012-06-25
著者
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Matsumoto Akira
Graduate School Of Marine Science And Technology Tokyo University Of Marine Science And Technology
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Hosokawa Chie
Health Research Institute, AIST, Ikeda, Osaka 563-8577, Japan
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Yasui Chikara
Graduate School of Science and Engineering & ORDIST, Kansai University, Suita, Osaka 564-8680, Japan
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Tawa Keiko
Health Research Institute, AIST, Ikeda, Osaka 563-8577, Japan
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Nishii Junji
RIES, Hokkaido University, Sapporo 001-0021, Japan
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Aota Hiroyuki
Graduate School of Science and Engineering & ORDIST, Kansai University, Suita, Osaka 564-8680, Japan
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Aota Hiroyuki
Graduate School of Science and Engineering & ORDIST, Kansai University, Suita, Osaka 564-8680, Japan
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Hosokawa Chie
Health Res. Inst., AIST:Grad. Sci. Eng., Kwansei Gakuin Univ.
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