Effect of Existence of Red Blood Cells in Trapping Performance of Microbubbles by Acoustic Radiation Force

スポンサーリンク

概要

• 論文の詳細を見る

• We have proposed a method to control microbubbles by making use of acoustic radiation force, which is generated with acoustic propagation, to correspond to therapeutic applications of ultrasound. By preventing bubbles from passing through the desired target area, the local concentration of bubbles can be enhanced. However, we have never experimentally confirmed this phenomenon under <i>in vivo</i> conditions or close to those. Thus, we carried out an experiment to evaluate the trapping performance of bubbles using a suspension of red blood cells (RBCs) and an artificial blood vessel. By defining the trapping index to evaluate the amount of trapped microbubbles, we have confirmed that the trapping performance was enhanced according to the concentration of RBCs and the sound pressure, but not according to the central frequency of ultrasound. The results indicate that the existence of RBCs near microbubbles contributed to the increase in the size of aggregations propelled against the vessel wall.

• 2011-07-25

著者

• Chiba Toshio

  National Center For Child Health And Development

• KOZUKA Teruyuki

  National Industrial Research Institute of Nagoya, AIST, MITI

• Masuda Kohji

  Graduate School Of Bio-applications And Systems Engineering Tokyo University Of Agriculture And Tech

• Kozuka Teruyuki

  National Institute of Advanced Industrial Science and Technology, Nagoya 463-8560, Japan

• Enosawa Shin

  National Center for Child Health and Development, Setagaya, Tokyo 157-8535, Japan

• Nakamoto Ryusuke

  Graduate School of Bio-Applications and Systems Engineering, Tokyo University of Agriculture and Technology, Koganei, Tokyo 184-8588, Japan

• Watarai Nobuyuki

  Graduate School of Bio-Applications and Systems Engineering, Tokyo University of Agriculture and Technology, Koganei, Tokyo 184-8588, Japan

• Koda Ren

  Graduate School of Bio-Applications and Systems Engineering, Tokyo University of Agriculture and Technology, Koganei, Tokyo 184-8588, Japan

• Taguchi Yuto

  Graduate School of Bio-Applications and Systems Engineering, Tokyo University of Agriculture and Technology, Koganei, Tokyo 184-8588, Japan

• Miyamoto Yoshitaka

  National Center for Geriatrics and Gerontology, Obu, Aichi 474-8511, Japan

• Kakimoto Takashi

  National Center for Child Health and Development, Setagaya, Tokyo 157-8535, Japan

• Masuda Kohji

  Graduate School of Bio-Applications and Systems Engineering, Tokyo University of Agriculture and Technology, Koganei, Tokyo 184-8588, Japan

• Chiba Toshio

  National Center for Child Health and Development, Setagaya, Tokyo 157-8535, Japan

• Watarai Nobuyuki

  Graduate School of Bio-Applications and Systems Engineering, Tokyo University of Agriculture and Technology, 2-24 Nakacho, Koganei, Tokyo 184-8588, Japan

• Nakamoto Ryusuke

  Graduate School of Bio-Applications and Systems Engineering, Tokyo University of Agriculture and Technology, 2-24 Nakacho, Koganei, Tokyo 184-8588, Japan

関連論文

• 超電導磁気センサを用いた医療計測応用
• 3P5-12 照射超音波のパラメータ変化に対する流路内マイクロカプセルの捕捉性能評価(ポスターセッション)
• 胎児外科治療の最新情報 (今月の臨床 胎児の診断と治療--最近のトピックス) -- (治療の最前線)
• 2P-47 音響放射力によるマイクロバブルの捕捉性能における赤血球の影響(ポスターセッション)
• Nanostructure Fabrication using PEG-based Polymers for Biomedical Applications
• Control of a Standing Wave Field Using a Line-Focused Transducer for Two-Dimensional Manipulation of Particles
• Simultaneous Observation of Motion and Size of a Sonoluminescing Bubble (Short Note)
• Quenching Mechanism of Multibubble Sonoluminescence at Excessive Sound Pressure
• Observation of a Sonoluminescing Bubble Using a Stroboscope
• Measurement of Distribution of Acoustic Radiation Force Perpendicular to Sound Beam Axis
• Relationship between a Standing-Wave Field and a Sonoluminescing Field
• Influence of the Sound Field on the Intensity of Sonoluminescence
• Effects of Nonlinearity in Development of Acoustic Streaming
• IS-1-3 New Eyes and Hands for Future Fetal Surgeons : advanced and emerging innovative technologies for in utero surgery for in utero surgery
• Evaluation of the Relationship Between the Viscoelastic Stress and Strain of Fetal Rat Skin as a Guide for Designing the Structure and Dynamic Performance of a Manipulator for Fetal Surgery
• Effect of Existence of Red Blood Cells in Trapping Performance of Microbubbles by Acoustic Radiation Force
• 胎児MMC手術用スタビライザ : 低侵襲貼付機構の基礎的検討
• 胎児保持のための水圧駆動軟性バルーンスタビライザの開発
• Active Path Selection of Fluid Microcapsules in Artificial Blood Vessel by Acoustic Radiation Force
• 1A2-L03 ワイヤ駆動を用いた胎児外科手術用パッチスタビライザの開発
• 胎児外科手術における三次元超音波のリアルタイム立体像表示システムの開発
• 胎児外科手術のための照射点可変レーザ内視鏡における照射点位置決め精度評価
• DEVELOPMENT AND EXPERIENCE OF TELE-ECHOGRAPHY SYSTEMS WITH AND WITHOUT ROBOTICS
• 双胎間輸血症候群のレーザ治療のための蛍光内視鏡
• 低侵襲胎児手術を対象とした細径多自由度マニピュレータの開発
• 歯車機構を用いた胎児外科用屈曲マニピュレータの研究開発
• リアルタイム2D超音波画像解析による胎児心疾患治療用集束超音波自動照射システムの開発
• Production of Local Acoustic Radiation Force to Constrain Direction of Microcapsules in Flow
• 3Pb5-13 微小気泡の凝集体形成による人工血管狭小部における流れの変化とその観測(ポスターセッション)
• 3Pb5-12 広帯域音源を用いた微小気泡の凝集体サイズの連続変化とその観測(ポスターセッション)
• 3Pb5-11 音響放射力に対向する流体中の微小気泡に対する複数音源を用いた能動的経路選択(ポスターセッション)
• 微小気泡の生体内制御支援のための超音波音場分布可視化システムの開発(超音波)
• 最新情報 助産師さんが知っていてほしい最近の胎児外科
• 術中リアルタイム3D超音波診断画像を用いた胎児外科手術ナビゲーションの開発
• 照射点可変レーザ内視鏡による呼吸動を有する血管の内視鏡下レーザ凝固術
• 微小気泡の生体内制御支援のための超音波音場分布可視化システムの開発
• Quenching Mechanism of Multibubble Sonoluminescence at Excessive Sound Pressure
• Experimental Study of Active Path Block in a Multi-Bifurcated Flow by Microbubble Aggregation
• Acoustic Standing-Wave Field for Manipulation in Air
• Measurement and Numerical Calculation of Force on a Particle in a Strong Acoustic Field Required for Levitation
• Noncontact Acoustic Manipulation in Air
• Study of an Acoustic Field in a Microchannel
• Experimental Study of Active Path Block in a Multi-Bifurcated Flow by Microbubble Aggregation (Special Issue : Ultrasonic Electronics) -- (Biomedical ultrasound)
• Production and Validation of Acoustic Field to Enhance Trapping Efficiency of Microbubbles by Using a Matrix Array Transducer (Special Issue : Ultrasonic Electronics) -- (Biomedical ultrasound)
• Experimental Study to Produce Multiple Focal Points of Acoustic Field for Active Path Selection of Microbubbles through Multi-bifurcation (Special Issue : Ultrasonic Electronics) -- (Biomedical ultrasound)
• S2-3 Relationship between the bubble temperature and main oxidant created inside an air bubble under ultrasound(Symposium (2) Cavitation, Sonoluminescence, and Bubble Dynamic)
• S5-1 Observations of native sonoluminescence structure with intensified CCD(Symposium (5) Industrial and Environmental Applications of Sonoprocessing)
• P-17 Correlation between Na^* emission and "chemically active" acoustic cavitation bubbles(Poster Presentations)

もっと見る 閉じる

スポンサーリンク