Production of Local Acoustic Radiation Force to Constrain Direction of Microcapsules in Flow

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概要

• 論文の詳細を見る

• We have ever reported our attempt to control the direction of microcapsules in flow by acoustic radiation force. However, the diameter of capsules was too large to be applied in vivo. Furthermore, the acoustic radiation force affected only the focal area because focused ultrasound was used. Thus, we have improved our experiment by using microcapsules as small as blood cells and introducing a plane wave of ultrasound. We prepared an artificial blood vessel including a Y-form bifurcation established in two observation areas. Then, we newly defined the induction index to evaluate the difference in capsule density in two downstream paths. As a result, the optimum angle of ultrasound emission to induct to the desired path was derived. The induction index increased in proportion to the central frequency of ultrasound, which is affected by the aggregation of capsules to receive more acoustic radiation force.

• 2010-07-25

著者

• Masuda Kohji

  Graduate School Of Bio-applications And Systems Engineering Tokyo University Of Agriculture And Tech

• Watarai Nobuyuki

  Graduate School of Bio-Applications and Systems Engineering, Tokyo University of Agriculture and Technology, 2-24 Nakacho, Koganei, Tokyo 184-8588, Japan

• Muramatsu Yusuke

  Graduate School of Bio-Applications and Systems Engineering, Tokyo University of Agriculture and Technology, 2-24 Nakacho, Koganei, Tokyo 184-8588, Japan

• Nakamoto Ryusuke

  Graduate School of Bio-Applications and Systems Engineering, Tokyo University of Agriculture and Technology, 2-24 Nakacho, Koganei, Tokyo 184-8588, Japan

関連論文

• Effect of Existence of Red Blood Cells in Trapping Performance of Microbubbles by Acoustic Radiation Force
• Active Path Selection of Fluid Microcapsules in Artificial Blood Vessel by Acoustic Radiation Force
• DEVELOPMENT AND EXPERIENCE OF TELE-ECHOGRAPHY SYSTEMS WITH AND WITHOUT ROBOTICS
• Production of Local Acoustic Radiation Force to Constrain Direction of Microcapsules in Flow
• Experimental Study of Active Path Block in a Multi-Bifurcated Flow by Microbubble Aggregation
• Experimental Study of Active Path Block in a Multi-Bifurcated Flow by Microbubble Aggregation (Special Issue : Ultrasonic Electronics) -- (Biomedical ultrasound)
• Production and Validation of Acoustic Field to Enhance Trapping Efficiency of Microbubbles by Using a Matrix Array Transducer (Special Issue : Ultrasonic Electronics) -- (Biomedical ultrasound)
• Experimental Study to Produce Multiple Focal Points of Acoustic Field for Active Path Selection of Microbubbles through Multi-bifurcation (Special Issue : Ultrasonic Electronics) -- (Biomedical ultrasound)

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