扁桃陰窩の電子顕微鏡学的研究

概要

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The palatine tonsil is a lympho-epithelial organ, and has the characteristic structure of crypts and lymphoepithelial symbiosis. Since the crypts and the lympho-epithelial symbiosis in tonsil are considered to be the sites of reaction with exogenous antigens, they are an important structure in immunological functions of the tonsil.<BR>Ultrastructure of the crypt epithelium has been made clear by electron microscopic studies. Many papers reported the relationship with the micropore (microcrypt) on epithelial surface of crypt, the lympho-epithelial symbiosis, and the micropore of basement membrane. We summarized these problems in this review.<BR>However, it is still unknown what mechanisms contribute to cell infiltrations and in uptake of exogenous substances. It is not explicated what relations exist between these problems and recurrent inflammation of recurrent tonsillitis or focal infection of affected tonsil. Both immunohistological studies and immunoelectron microscopic studies are necessary to determine the real mechanism on immunological bases.
耳鼻咽喉科臨床学会の論文