Influence of human albumin on antibacterial activities of biapenem
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概要
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We investigated the <I>in vitro</I> antibacterial activity of biapenem (BIPM), imipenem (IPM), penicillin G (PCG) and ampicillin (ABPC) with the presence of human serum albumin.<BR>As the test organism, <I>Staphylococcus aureus</I> ATCC 25923, <I>Eschrichia coil</I> ATCC 25922, three clinical isolates of<I> Streptococcus anginosus</I> and three clinical isolates of <I>Streptococcus sanguis</I> were used.<BR>The MICs and MBCs of several agents against these strains were measured in Mueller-Hinton broth with or without 5g/dl of human serum albumin by the broth dilution method.<BR>The presence of human serum albumin in the medium influenced the antibacterial activity of PCG, whereas not those of biapenem, IPM and ABPC.
- 公益社団法人 日本化学療法学会の論文
公益社団法人 日本化学療法学会 | 論文
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