CLINICAL STUDY OF MEROPENEM ON PULMONARY INFECTIONS
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概要
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Meropenem, a new carbapenem antibiotic for injection, was administered to 6 patients with pulmonary infection (pneumonia 4, diffuse panbronchiolitis 1, chronic bronchitis 1). The clinical response was excellent in 2 cases and good in 4. Bacteriologically, 4 strains of 3 species (<I>Streptococcus pneumoniae</I> 2, <I>Corynebacterium pseudodiphtheriticum</I> 1, <I>Pseudomonas aeruginosa</I> 1) were detected as causative bacteria in 4 cases, and 3 of these strains except <I>P. aeruginosa</I> were eliminated.<BR>Although none of the patients developed side effects, elevation of S-GOT and S-GPT was found in 2 cases, elevation of LDH in one, and increased eosinophils, elevation of LDH and decreased platelet count in one. Although changes in laboratory values were rather frequent, viz. in 4 of 6 patients, all were slight and transient.
- 公益社団法人 日本化学療法学会の論文
公益社団法人 日本化学療法学会 | 論文
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