THERAPEUTIC EFFECT OF T-3262, A NEW PYRIDONE CARBOXYLIC ACID ON VARIOUS EXPERIMENTAL INFECTIONS
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概要
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The therapeutic effects of T-3262 on various experimental infections in mice were studied in comparison with norfloxacin (NFLX) and ofloxacin (OFLX).<BR>1) The therapeutic effect of T-3262 was equal or superior to those of OFLX and NFLX against systemic infection in mice treated with immunosupressive cyclophosphamide or azathioprine.<BR>2) On urinary tract infection with Gram-negative bacteria in mice, the therapeutic effect of T-3262 was equal to those of OFLX, and was superior to those of NFLX.<BR>3) On pneumonia with <I>Klebsiella pneumoniae</I> and <I>Pseudomonas aeruginosa</I> in mice, the therapeutic effect of T-3262 was equal or superior to those of OFLX and NFLX.<BR>4) On subcutaneous abscess with <I>Staphylococcus aureus</I> in mice, the therapeutic effect of T-3262 was superior to those of OFLX and NFLX.
- 公益社団法人 日本化学療法学会の論文
公益社団法人 日本化学療法学会 | 論文
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