CLINICAL STUDY ON TE-031 (A-56268) AGAINST RESPIRATORY INFECTIONS
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We carried out a clinical study on an oral macrolide antibiotic, TE-031 (A-56268).<BR>1. Clinical effect of TE-031 against respiratory infections (bacterial pneumonia 12 cases, mycoplasma pneumonia 3, psittacosis pneumonia 1, bronchiectasis 1, diffuse panbronchiolitis 1 and upper respiratory infection 5) was excellent in 1 case, good in 21, and fair in I.<BR>2. Bacteriologically, of causal bacteria isolated from 10 cases, 5 strains of <I>S. pneumoniae</I>, I of <I>S. aureus</I>, 3 of <I>H. influenzae</I> and lof <I>B. catarrhalis</I>, completely disappeared after administration.<BR>3. of side-effect caused by TE-031 was observed. Abnormal laboratory findings were increased GOT and GPT in 3 cases, increased GPT in 1, and eosinophilia in 2, all of which were slight and recovered to normal after the end of administration.<BR>From the above results, TE-031 is considered a useful drug against respiratory infections.
- 公益社団法人 日本化学療法学会の論文
公益社団法人 日本化学療法学会 | 論文
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