ANTIMICROBIAL ACTIVITY AND CLINICAL EVALUATION OF NY-198
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概要
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We examined the MICs of NY-198 against 77 strains of <I>P. aeruginosa</I> isolated from blood cultures as well as 20 of <I>S. aureus</I> and 19 of <I>E. faecalis</I>, which were resistant to OFLX by disc-sensitivity study. With regard to <I>P. aeruginosa</I>, MIC distribution of NY-198 was very similar to that of OFLX. Cross-resistance was observed among new quinolones against <I>S. aureus</I> and <I>E. faecalis</I>, which was resistant to OFLX.<BR>NY-198 was administered to 17 patients with RTI, 4 with UTI and 1 with cholecystitis. All patients responded satisfactorily. Abdominal distension, eosinophilia and slight elevation of transaminases were observed in one case each. Further investigation is necessary on the optimal daily dose of NY-198.
- 公益社団法人 日本化学療法学会の論文
公益社団法人 日本化学療法学会 | 論文
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