CLINICAL STUDY ON CEFUROXIME AXETIL (CXM-AX)
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A new oral cephem antibiotic, cefuroxime axetil (CXM-AX) was administered to total 28 patients consisting of 26 with respiratory tract infections and 2 with urinary tract infections, and its efficacy and safety were studied. The study was carried out from September, 1984 to May, 1985. The patients consisted of 11 adult males and 17 adult females in this study. The mean age of the total patients was 57.5 years (range: 18-80).<BR>CXM-AX was given three times a day at a dose of 250 mg or 500 mg in the patients with respiratory tract infections and at a dose of 250 mg in the patients with urinary tract infections. The duration of therapy ranged from 3 to 14 days, the total dose ranged from 2.25 to 21.0 g.<BR>The therapeutic effect was ' Excellent ' in 1 patient, ' Good ' in 18, 'Fair' in2, 'Poor' in 3, ' undetermined ' in 4, with a high effectiveness rate of 79.2%. As an adverse event, diarrhea was observed in one patient. Laboratory tests revealed decrease in neutrophil in one case. however, these symptom and finding were mild and no severe side effects caused by the drug were observed.
- 公益社団法人 日本化学療法学会の論文
公益社団法人 日本化学療法学会 | 論文
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