CLINICAL STUDIES ON BRL25000 (CLAVULANIC ACID-AMOXICILLIN) IN THE FIELD OF INTERNAL MEDICINE
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概要
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BRL25000, one tablet of the drug containing 250 mg of AMPC and 125 mg of CVA, was administered to 13 patients with urinary or pulmonary infections.<BR>Effective results were obtained in 9 out of 10 cases with urinary infections, and one out of 3 cases with pulmonary infections.<BR>No side effects except 1 case with abdominal pain and diarrhea, were observed.<BR>This drug shows very strong antibacterial activity against several strains which are resistant to AMPC. These include <I>E. coli, K. pneumoniae, P. mirabilis</I> and <I>E. cloacae</I>.<BR>It is considered that BRL25000 may constitute an advance to the antibiotic treatment of β-lactamase proplucing bacterial infections.
- 公益社団法人 日本化学療法学会の論文
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