外来尿路感染症患者に対するCefadroxilの臨床的評価 (Cefadroxil(CDX,BL-S578)<特集>)

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Cefadroxil, a new oral cephalosporin. was administered in 31 cases of urinary tract infection who visited the Department of Urology. Hospital attached to School of Medicine, Tokushima University, and the drug was evaluated clinically as follows.<BR>1) Dosage: Cefadroxil was administered for 3 to 7 days respectively at a daily dose of 750 mg (divided into 3 times) in simple urinary tract infection, while a daily dose of 1, 500 mg (divided into 3 times) in complicated urinary tract infection.<BR>2) Clinical result: Efficacy rate obtained was 89.5% in simple urinary tract infection, whereas 58.3% in complicated urinary tract infection.<BR>3) Bacteriological effect: Bacteria were eradicated in 20 strains (64.5%), decreased in 4 strains (12.9%), and unchanged in 7 strains (22.6%) out of 31 Strains. It was noteworthy that E. cdi was eradicated in 14 strains (82.4%) out of 17 strains, decreased in 2 strains, and unchanged in 1 strain.<BR>4) Side effect: No side effect was observed with the drug except an exanthema was noticed in 1 case.
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