AMINODEOXYKANAMYCIN TREATMENT OF URINARY INFECTION
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概要
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Aminodeoxykanamycin, 2′-amino-2′-deoxy-kanamycin (AKM) has stronger effect against most pathogenic bacteria than KM and is a little more toxic than KM. This toxicity is, however, not so strong as that of gentamicin or paromomycin (aminosidine) which have been used recently in Japan. Thus, ' we tested both the effect and side effect of AKM using by far small dosis as that of KM, and following results were obtained.<BR>1. Aminodeoxykana mycin is very effective in the treatment of urinary infection of <I>E. coli, Prams, Staph.</I> and of mixed flora of<I> E. coli</I> with <I>Staph., </I> <I>E. coli</I> with <I>Pseudomonas</I> and so on.<BR>2. Dosage. Most cases were cured with daily dosis of 100 mg which was given once a day or in two injections. Some times daily dosis was 200 mg and only for acute gonorrhea it was 400 mg.<BR>3. Duration of administration was very short; in most cases 3-5 days were necessary.
- 公益社団法人 日本化学療法学会の論文
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