OPHTHALMIC USE OF GENTAMICIN
スポンサーリンク
概要
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Gentamicin, a new highly inhibitory antibiotic for gram-negative and gram-positive organisms, was administered to 7 cases of suppurative diseases of the eye with favorable results in 5 cases. In most of these cases topical instillation of ophthalmic solution or ointment of 0.3% gentamicin and subconjunctival injection of 10∼20 mg gentamicin were performed so that high intraocular penetration was rapidly obtained.<BR>Serum and aqueous levels of genatamicin were determined with <I>Bacillus subtilis</I> following systemic or topical administration in the rabbit eye. A higher intraocular penetrarion was obtained by topicl administration than by systemic, especially in the previously paracentetic eye.
- 公益社団法人 日本化学療法学会の論文
公益社団法人 日本化学療法学会 | 論文
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