PROSTATIC TISSUE LEVELS OF DL-8280
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概要
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Prostatic tissue levels of DL-8280 were determined in 17 patients with benign prostatic hypertrophy, prostatic cancer and bladder cancer.<BR>The concentrations of DL-8280 in prostatic tissue and serum were measured after single oral dose of DL-8280 200 mg by the high performance liquid chromatography.<BR>The maximum concentration of DL-8280 in the prostatic tissue was 6.25 peg and prostatic tissue/serum ratio was 2.45.<BR>Penetration of DL-8280 into prostate was excellent.<BR>The clinical effectiveness of DL-8280 could be expected on bacterial prostatitis.<BR>There was no difference between the internal gland and external gland regarding the tissue levels of DL-8280.
- 公益社団法人 日本化学療法学会の論文
公益社団法人 日本化学療法学会 | 論文
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