Netilmicinの臨床的検討 (Netilmicin(NTL)<特集>)
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概要
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Netilmicin sulfate, a new semisynthetic aminoglycoside antibiotic, was injected to 9 patients with urinary tract infection (5 patients) and with respiratory tract infection (4 patients). A daily dose of Netilmicin was 150-200mg by intramuscular injection and duration of Netilmicin therapy was for 7 to 14 days.<BR>The results were as follows.<BR>1. Clinical response to Netilmicin therapy of urinary tract infection was excellent in 2 cases, good in 1 case, fair in 2 cases and that of respiratory tract infection was good in 1 case, fair in 2 cases, poor in 1 case. Effective rate was 44.4%.<BR>2. Netilmicin was especially effective to infections by <I>E. coli</I> and urinary tract infection by <I>P seudomonas aeruginosa</I>.<BR>3. Anemia and thrombocytopenia, as side effects, were observed in one case, but they were all transient. Neither nephrotoxicity nor ototoxicity of Netilmicin were clinically observed.
- 公益社団法人 日本化学療法学会の論文
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