Nipple-preserving total glandectomy for noninvasive breast carcinoma

概要

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Between January 1978 and March 1995, 37 patients with noninvasive breast carcinoma (excluding Paget's disease) were treated at our department. Out of the 37 patients, 20 were treated with nipple-preserving total glandectomy. Eighteen had noninvasive ductal carcinoma and two had lobular carcinoma in situ. All eighteen noninvasive ductal carcinomas were of the non-comedo type. Nineteen patients received nipple-preserving total glandectomy and axillary dissection. One patient was initially treated with microdochectomy, and then additional nipple-preserving total glandectomy and axillary dissection were done to remove positive margins. All patients received tamoxifen as adjuvant therapy, but no adjuvant radiotherapy was given. These 20 patients had no cancer infiltration of the nipple base and all remain alive without disease after 63 months on the average.In conclusion, breast surgeons should always take nipple-preserving total glandectomy into consideration for patients with noninvasive breast cancer.
日本癌病態治療研究会の論文