ATYPICAL COGAN'S SYNDROME SUCCESSFULLY TREATED WITH CORTICOSTEROIDS AND PULSE CYCLOPHOSPHAMIDE THERAPY
スポンサーリンク
概要
- 論文の詳細を見る
An-18-year-old woman was admitted to the medical center near her home with complaints of high fever and severe headache in June 1995. A diagnosis of adult-onset Still's disease was suspected and 50 mg/day of prednisolone was orally administered. In early April 1997, the patient suffered from sudden bilateral hearing loss and high fever. Pure tone audiogram taken at the same time showed an asymmetric bilateral neurosensorial hearing loss. A diagnosis of Cogan's syndrome was made. Administration of 60 mg prednisolone daily improved fever. Audiogram taken one month after administration of prednisolone showed improvement in the right ear. Monthly cyclophosphamide pulse therapy 700 mg combined with oral prednisolone was instituted. This combination therapy enabled the successful tapering of prednisolone without recurrence of hearing loss. Combined corticosteroid and pulse cyclophosphamide therapy would appear to be one effective regimen for Cogan's syndrome.
- 福島医学会の論文
著者
-
WATANABE Kenya
Department of Internal Medicine II, Fukushima Medical University School of Medicine
-
Yoshida Minako
Department Of Internal Medicine Ii Fukushima Medical University School Of Medicine
-
Suzuki Shuzo
Department Of Internal Medicine Ii Fukushima Medical University School Of Medicine
-
Nishimaki Tomoe
Department Of Internal Medicine Ii Fukushima Medical College
-
Yoshioka Ryoji
Department Of Internal Medicine Ii Fukushima Medical University School Of Medicine
-
Kasukawa Reiji
Department Of Internal Medicine 2 Fukushima Medical University School Of Medicine
-
WATANABE KENYA
Department of Gastroenterology, Fujita General Hospital
-
KASUKAWA REIJI
Department of Internal Medicine II, Fukushima Medical University School of Medicine
-
SHINZAWA JYOTARO
Department of Internal Medicine II, Fukushima Medical University School of Medicine
関連論文
- Synovial Mononuclear Cells Consist with T Cells Which Produce High Levels of Tumor Necrosis Factorα
- Detection and Monitoring of Methotrexate-associated Lung Injury Using Serum Markers KL-6 and SP-D in Rheumatoid Arthritis
- Protein-losing Enteropathy Exacerbated with the Appearance of Symptoms of Systemic Lupus Erythematosus
- Takayasu's Arteritis in a 69-year-old Woman
- Two Patients with Polymyositis or Dermatomyositis Complicated with Massive Pleural Effusion
- Primary Sjogren's Syndrome Complicated by Sarcoidosis
- Magnetic Resonance Imaging Findings in Primary Amyloidosis-associated Arthropathy
- Expression of immunoreactivities to 75 kDa nerve growth factor receptor, trk gene product and phosphotyrosine in granular cell tumors
- Anti-Calreticulin Antibodies in Patients with Inflammatory Bowel Disease
- A case of systemic lupus erythematosus complicated by pure red cell aplasia and idiopathic portal hypertension after thymectomy
- Lipo prostaglandin E1 reduces the production of CXC chemokines in endotoxin-induced rat liver injury
- Analysis of peripheral blood mononuclear cell stimulated with pyruvate dehydrogenase complex, T-cell receptors from patients with primary biliary cirrhosis
- High serum levels of vascular endothelial growth factor in patients with human hepatocellular carcinoma
- Antithrombin III stimulates prostaglandin I_2 production by cultured rat hepatic sinusoidal endothelial cells
- Viral, fungal and mycobacterial infections in patients with systemic lupus erythematosus
- Selective expansion of large limphoblasts expressing V_β6.1-3 or 7 in synovial fluid from patients with rheumatoid arthritis
- Clinicolaboratory characteristics of patients with primary biliary cirrhosis associated with CREST symptoms
- Pleomorphic Carcinoma of the Lung Associated with Loss of Heterozygosity of p53 Gene
- Pulmonary Hypertension in Connective Tissue Disease
- Modulation of adhesion molecules and carbohydrate antigens on granulocytes of patients with rheumatoid arthritis treated with granulo-monocytapheresis
- Treatment of rheumatoid arthritis by granulo-monocytapheresis
- Primary sclerosing cholangitis with marked eosinophilic infiltration in the liver
- Mixed Connective Tissue Disease with Severe Pulmonary Hypertension and Extensive Subcutaneous Calcification
- T-cell clonality of peripheral blood from patients with chronic hepatitis C before and after treatment with interferon α
- Multiple primary neoplasms and hepatitis C virus infection in oral cancer patients
- Lymphocyte adhesion to cultured endothelial cells is impaired in patients with systemic lupus erythematosus
- ANALYSIS OF PROGNOSTIC FACTORS IN PATIENTS WITH GASTRIC VARICES AFTER ENDOSCOPIC TREATMENT
- Two Anomalous Cases of the Hepato-mesenteric and the Gastro-splenic Trunks Independently Arising from the Abdominal Aorta.
- An Anomalous Case of the Hepato-spleno-mesenteric and the Gastro-phrenic Trunks Independently Arising from the Abdominal Aorta.
- ANTI-CALRETICULIN ANTIBODIES IN PATIENTS WITH INFLAMMATORY BOWEL DISEASE
- EFFECT OF ISOSORBIDE DINITRATE ON GASTRIC BLOOD FLOW IN RATS WITH LIVER CIRRHOSIS DETERMINED BY ANALYZING GASTRIC BLOOD FLOW, PORTAL VEIN PRESSURE AND BLOOD GAS
- APPEARANCE OF RECTAL VARICES IN EXTRAHEPATIC PORTAL OBSTRUCTION AFTER TREATMENT FOR ESOPHAGO-GASTRIC VARICES : A CASE REPORT
- A CASE OF ESOPHAGEAL SMALL CELL CARCINOMA ASSOCIATED WITH HYPERCALCEMIA CAUSING SEVERE ACUTE PANCREATITIS
- A Granular Cell Tumor of the Buccal Mucosa. A Case Report.:A Case Report
- USEFULNESS OF INTRAOPERATIVE ESOPHAGOGASTRO-DUODENOSCOPY IN A PATIENT WITH LUPUS ENTERITIS
- USEFULNESS OF ENDOSCOPIC ULTRASONOGRAPHIC ANALYSIS OF VARICEAL HEMODYNAMICS FOR THE TREATMENT OF ESOPHAGEAL VARICES
- ATYPICAL COGAN'S SYNDROME SUCCESSFULLY TREATED WITH CORTICOSTEROIDS AND PULSE CYCLOPHOSPHAMIDE THERAPY
- HLA-A2-RESTRICTED CYTOTOXIC T LYMPHOCYTE ACTIVITY DURING INTERFERON BETA THERAPY IN PATIENTS WITH CHRONIC HEPATITIS C
- Efficacy of the Extracorporeal Granulotrap G-1 Column in a Rabbit Model of Induced Arthritis(Workshop1-12)