Posterior Reversible Encephalopathy Syndrome due to Hypercalcemia Associated with Parathyroid Hormone-related Peptide: A Case Report and Review of the Literature

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概要

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• We herein report the case of a 58-year-old man with advanced esophageal carcinoma who developed posterior reversible encephalopathy syndrome (PRES). He initially presented with a severe consciousness disturbance. A subsequent examination revealed hypercalcemia and an elevated serum parathyroid hormone-related peptide (PTHrP) level. Magnetic resonance imaging performed on admission and 24 days later showed reversible widespread white matter abnormalities, which confirmed a diagnosis of PRES. The patient's clinical and radiological manifestations improved upon normalization of the serum calcium level. To the best of our knowledge, this is the first report describing hypercalcemia-induced PRES occurring in association with elevated PTHrP.

• 社団法人 日本内科学会の論文

著者

• Katayama Yasuo

  Department Of Internal Medicine Divisions Of Neurology Nephrology And Rheumatology Nippon Medical Sc

• Nakajima Nobuhito

  Department of Neurology, Kitamurayama Public Hospital, Japan

• Nagayama Hiroshi

  Department of Internal Medicine, Division of Neurology, Nephrology and Rheumatology, Nippon Medical School, Japan

• Ueda Masayuki

  Department of Internal Medicine, Isumi Medical Center, Japan

• Yamazaki Mineo

  Department of Neurology, Nippon Medical School, Japan

• Yamazaki Mineo

  Department of Neurology, Nippon Medical School

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